P27 expression in pleomorphic salivary gland adenoma.

Aim Of The Study: This study aims to characterise alterations in the immunohistochemical expression of p27 in normal tissue of the salivary gland surrounding pleomorphic adenoma and in the tumour cells of pleomorphic adenoma.

Material And Methods: A retrospective study of data including 120 cases of pleomorphic adenomas (66 female, 54 male) retrieved from the files of the Oral Pathology Departments of Aleppo University, Syria and Al-Farabi Dental and Nursing College. Immunohistochemical expression against p27 was examined in the selected cases.

p53 expression in pleomorphic adenoma of salivary glands: A systematic review and meta-analysis.

Objective: There are conflicting data regarding immunohistochemical expression of p53 in pleomorphic adenoma. This systematic review and meta-analysis aimed to examine whether p53 expression has a role in the pathogenesis of pleomorphic adenoma.

Design: A comprehensive literature search for relevant studies published from 2000 up to end of 2014 was performed using PubMed, EMBASE and the Cochrane Library Databases.

Impact of simulation training on Jordanian nurses' performance of basic life support skills: A pilot study.

Background: Providing efficient basic life support (BLS) training is crucial for practicing nurses who provide direct patient care. Nevertheless, data addressing the impact of BLS courses on the skills and performance of Jordanian nurses are scarce. This study aimed to assess the effectiveness of a BLS simulation training on Jordanian nurses' skill improvement in cardiopulmonary resuscitation.

World Workshop on Oral Medicine VI: Controversies regarding dental management of medically complex patients: assessment of current recommendations.

Objectives: Current recommendations for safe and effective dental management are less than optimal for some medical conditions because of limited evidence, conflicting conclusions, or both. This review (1) compiled and evaluated dental management recommendations for select medical conditions; (2) summarized recommendations and their assigned levels of evidence; (3) identified areas of conflict, ambiguity, or both; and (4) identified issues that warrant future research, enhanced consensus statements, or both.

Study Design: Systematic literature searches were performed for guideline publications, systematic and narrative reviews, and opinion documents containing recommendations for (1) medication-related osteonecrosis of the jaw (MRONJ); (2) cardiovascular diseases (CVDs); (3) prosthetic joints (PJs); and (4) systemic steroid therapy (SST).

Histological Evaluation of Allium sativum Oil as a New Medicament for Pulp Treatment of Permanent Teeth.

Objective: The objective of this study was to evaluate the histo pathology effects of two medicaments Allium sativum oil and formocresol on the remaining pulp tissue of the permanent teething children.

Materials And Methods: A total of 18 premolars were included in this study. Two sound premolars were extracted and subjected to histological examination to show the normal pulp tissue.

Cyclic fatigue resistance of OneShape and WaveOne instruments using different angles of curvature.

This study compared the cyclic fatigue resistance of OneShape (OS) instrument which used continuous rotation with WaveOne (WO) instrument which used reciprocating motion. OS size 25, 0.06 taper and WO primary size 25, 0.

Photodynamic therapy in treatment of oral lichen planus.

Oral lichen planus (OLP) is a relatively common chronic immunologic mucocutaneous disorder. Although there are many presenting treatments, some of them proved its failure. Recently, the use of photodynamic therapy (PDT) has been expanding due to its numerous advantages, as it is safe, convenient, and non-invasive and has toxic effect towards selective tissues.

Comparison of amlodipine with cilnidipine on antihypertensive efficacy and incidence of pedal edema in mild to moderate hypertensive individuals: A prospective study.

To compare amlodipine with cilnidipine on antihypertensive efficacy and incidence of pedal edema in hypertensive individuals. This was a three months prospective, observational study done at the tertiary care center of Karnataka, India. A total number of 60 (n = 60) newly diagnosed hypertensives (≥140/90) of either gender, attending outpatient department of medicine, were included in the study.

The magic of magic bugs in oral cavity: Probiotics.

The aim of this review is to present an update about the current status of probiotics in the field of dentistry. Oral infections are the most common forms of infections. It is necessary to understand the role of the ecology and microbiology of the oral cavity in better understanding of the pathogenesis of various oral diseases.

Oral manifestations of Parry-Romberg syndrome: A review of literature.

Parry-Romberg syndrome (PRS) or progressive facial hemiatrophy is a developmental craniofacial disorder of unknown etiology characterized by a slowly progressive unilateral facial atrophy. It is associated with different systemic manifestations particularly, maxillofacial, neurologic and ophthalmologic abnormalities. Dentists must be aware of PRS to identify this invalidating disorder.

Immunohistochemical comparison of p53, Ki-67, CD68, vimentin, α-smooth muscle actin and alpha-1-antichymotry-psin in oral peripheral and central giant cell granuloma.

Introduction: Giant cell lesions are characterised histologically by multinucleated giant cells in a background of ovoid to spindle-shaped mesenchymal cells. There is a major debate whether these lesions are separate entities or variants of the same disease. Our aim was to study the nature of multinucleated and mononuclear cells from peripheral giant cell granuloma (PGCG), and central giant cell granuloma (CGCG) and giant cell tumor (GCT) of long bones using immunohistochemistry evaluation and to determine whether there is a correlation between recurrence and the markers used.

Human Epidermal Growth Factor Receptor 2 (HER2/neu) in Salivary Gland Carcinomas: A Review of Literature.

The aim of our study is to assess the relation of human epidermal growth factor receptor 2 or HER2/neu with the development of salivary gland carcinomas and use of Herceptin in the treatment of these cancers. A literature search was conducted using MEDLINE accessed via the National Library of Medicine PubMed interface searching for articles from 1994 up to 2014 relating to the existence of HER-2 protein and gene in salivary gland carcinomas and HER2/neu targeted therapy, written in English language. Almost all the studies in literature reported a frequent over expression and amplification of HER2/nue in salivary duct carcinomas (SDC) compared to other salivary gland cancers.

Bilateral radicular cyst in mandible: an unusual case report.

A radicular cyst is one of the furthermost everyday odontogenic cysts of the anterior maxilla, not regularly comprehended in youth. They are found mostly at the apices of the tooth (periapical cyst), lateral surface of the roots (lateral radicular cyst) and remains in the jaw after removal of the offending tooth (residual cyst). The radicular cyst has been catalogued as an inflammatory cyst, as an outcome to pulpal necrosis succeeding caries, with a linked periapical inflammatory reaction.

Violence against nurses in emergency departments in jordan: nurses' perspective.

Violence against nurses in emergency departments (EDs) has become a widespread phenomenon affecting nurses' job satisfaction and work performance. Literature is scarce regarding prevalence rates and causes of violence directed toward nurses in Jordan. The present study investigated violence experienced by Jordanian nurses in EDs and causes of violence from their perspectives.

Repair bond strength of resin composite to a novel CAD/CAM hybrid ceramic using different repair systems.

This study evaluated the repair bond strength of a nanohybrid resin composite to a novel CAD/CAM hybrid ceramic based on four intraoral ceramic repair systems. Vita Enamic (VE) CAD/CAM hybrid ceramic was used in this study. Specimens were divided into five test groups according to the repair method performed on the ceramic surface: Gr C (No treatment; control); Gr CZ (Cimara Zircon); Gr PR (Porcelain Repair); Gr CR (Clearfil Repair); and Gr CS (CoJet system).

Evaluation of bacterial contamination in a clinical environment.

Background: Although the contamination of the dental environment and personnel through aerosol contamination is a definite source of cross contamination; there is little data on the microbial involvement of the dental environment.

Materials And Methods: A total of 100 samples were taken from various inanimate surfaces in the clinical dental setting were collected aseptically by rotating sterile swabs moistened with peptone water over the surfaces of the samples and then inoculated into brain heart infusion broth and incubated at 37°C aerobically overnight. Subcultures were made on 5% sheep blood agar and MacConkey agar plates and incubated at 37°C for 24 h.

Maspin as a tumour suppressor in salivary gland tumour.

Maspin is a protein that belongs to serin protease inhibitor (serpin) superfamily. The purpose of this study was to review the literature concerning the expression of maspin in salivary gland tumours. A literature search was done using MEDLINE, accessed via the National Library of Medicine PubMed interface.

Tuberculous lymphadenitis: early diagnosis and intervention.

Tuberculosis (TB) is reported to be one of the most widespread systemic bacterial infectious diseases frequently triggered by Mycobacterium TB. It is anticipated to have a prevalence of approximately 8 million individuals each year, and 3 million individuals die of complications related with the ailment. We present a case of a 5-year-old female patient with a painless swelling in her left submandibular region.

An unusual side effect of Ibuprofen post dental therapy: increased erectile and libido activity.

Nonsteroidal anti-inflammatory drugs are the most commonly used medications for pain control in dentistry. The reported adverse effects include gastrointestinal and cardiovascular events, alterations in renal function, and effects on blood pressure, hepatic injury, and platelet inhibition which can lead to increased bleeding. This case report describes an unusual rare adverse event of the use of ibuprofen for pain control post restorative treatment.

Influence of mouth breathing on the dentofacial growth of children: a cephalometric study.

Background: The involvement of mouth breathing, facial, and structural growth alterations, especially during childhood has been discussed in medical and dental literature. The relevance of airway obstruction and its assumed effect on facial growth continues to be debated.

Materials And Methods: This study was aimed at assessing the dental and soft tissue abnormalities in mouth breathing children with and without adenoid hypertrophy.

Clinical and Radiographic Evaluation of Allium sativum Oil as a New Medicament for Vital Pulp Treatment of Primary Teeth.

Background: The objective of this study was to compare between the clinical and radiographic effects of Allium sativum oil and those of formocresol in vital pulpotomy in primary teeth.

Materials And Methods: A total of 20 children age ranged from 4 to 8 years were included in the study. In every one of those children, the primary molars indicated for pulpotomy.

Prevalence and awareness of halitosis in a sample of Jordanian population.

Objectives: This study was conducted to estimate the prevalence and awareness of halitosis among the subjects of a population, and also to compare the results of Halimeter(®) readings to self-estimation of halitosis and to assess the relationship between halitosis and oral health.

Materials And Methods: A sample of 205 employees from the Jordan University for Science and Technology (JUST) were selected as study subjects. A standardized questionnaire focusing on dental hygiene, self-reported halitosis, and smoking was filled by all participants.

Hemophilia A: Dental considerations and management.

Aim: To review hemophilia A with emphasis on its oral manifestations, investigations, and dental management.

Materials And Methods: Search was conducted using internet-based search engines, scholarly bibliographic databases, PubMed, and Medline with key words such as "Hemophilia A," "factor VIII," "bleeding and clotting disorders," and "dental management."

Results: Hemophilia comprises a group of hereditary disorders caused due to the deficiency of one or more clotting factors leading to prolonged clotting time and excessive bleeding tendencies.

Public awareness and knowledge of oral cancer in Yemen.

Background: Oral cancer is in increasing in incidence in Yemen and indeed worldwide. Knowledge regarding risk factors and early signs in the general population can help in prevention and early detection of the disease.

Purpose: The aim of this study was to assess the level of awareness and knowledge of oral cancer in the general population in Yemen.

Influence of surface treatments on bond strength of metal and ceramic brackets to a novel CAD/CAM hybrid ceramic material.

This study evaluated the effect of four different surface treatments methods on the shear bond strength (SBS) of ceramic and metal brackets to Vita Enamic (VE) CAD/CAM hybrid ceramic. A total of 240 plates (10 mm × 10 mm × 3 mm) were cut from VE ceramic blocks and divided into two groups. In each group, four subgroups were prepared by hydrofluoric acid (HF); phosphoric acid (H3PO4); diamond ceramic grinding bur; and silica coating using CoJet system (CJ).