The Evaluation of the Genetic Variation Types of the Gene by Next-Generation Sequencing and Their Effects on Bilirubin Levels in Obese Children.

Obesity is a major nutritional problem with an increasing prevalence among children and adolescents. The () gene encodes the UDP-glucuronosyl transferase enzyme, converting the toxic form of bilirubin to a soluble, nontoxic form. There are yet to be studies on the evaluation of the variant types detected by next-generation sequencing (NGS) and their effects on bilirubin levels in nonsyndromic obese children.

Evaluation of the protective and therapeutic effects of extra virgin olive oil rich in phenol in experimental model of neonatal necrotizing enterocolitis by clinical disease score, ınflammation, apoptosis, and oxidative stress markers.

Background And Aim: Necrotizing Enterocolitis (NEC) is an inflammation-associated ischemic necrosis of the intestine. To investigate the effects of extra virgin olive oil (EVOO) on inflammation, oxidative stress, apoptosis, and histological changes in NEC-induced newborn rats.

Materials And Methods: 24 rats were randomly divided into three groups: control, NEC and NEC + EVOO.

Evaluation of both expression and serum protein levels of caspase-8 and mitogen-activated protein kinase 1 genes in patients with different severities of COVID-19 infection.

Aim: The current study aimed to evaluate the effects of caspase-8 (CASP8) and mitogen-activated protein kinase 1 (MAPK1) gene expression levels and their products on preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Methods: A total of 40 patients (men, 15 [37.5%]; women, 25 [62.

Clinical and Molecular Findings in a Turkish Family Who Had a (c.869- 1G>A) Splicing Variant in PSEN1 Gene with A Rare Condition: The Variant Alzheimer's Disease with Spastic Paraparesis.

Background: Early-onset Alzheimer's disease (EOAD) is commonly diagnosed with an onset age of earlier than 65 years and accounts for 5-10% of all Alzheimer's disease (AD) cases. To date, although only 10-15% of familial EOAD cases have been explained, the genetic cause of the vast proportion of cases has not been explained. The variant Alzheimer's disease with spastic paraparesis (var- AD) is defined as a rare clinical entity characterized by early-onset dementia, spasticity of the lower extremities, and gait disturbance.

YouTube videos as a source of information concerning Behçet's disease: a reliability and quality analysis.

In this study, we aimed to investigate the reliability and quality of YouTube videos concerning Behçet disease, for the first time in the literature. The most viewed 50 YouTube videos about Behçet disease were included. Study data used in the analysis included video length, image type, video content, uploaders, time since the date of upload, the number of total views, daily views, and the numbers of like, dislike and comments.

Is There a Relationship Between Kinesiophobia and Physical Activity Level in Patients with Knee Osteoarthritis?

Objective: To investigate the levels of kinesiophobia, physical activity, depression, disability, and quality of life in patients with knee osteoarthritis.

Design: A cross-sectional study.

Setting: A tertiary health care center.

Isokinetic Analysis of Trunk Muscles in Stroke Patients and its Association with Functional Parameters.

Objective: The purpose of our study is to investigate the association of balance, motor and functional development parameters with trunk muscles via isokinetic analysis in stroke patients due to cerebrovascular event.

Methods: The study included 91 stroke patients and 28 healthy controls. Brunnstroom staging (BS) for motor functions, functional independence measurement (FIM) and Barthel index (BI) for disability, Berg balance scale (BBS) balance test for balance, Rivermead motor evaluation (RMA) for mobility, and mini-mental test (MMT) for cognitive function were used.