Antiplasmodial Activity and Phytochemical Constituents of Selected Antimalarial Plants Used by Native People in West Timor Indonesia.

Objectives: To document traditional antimalarial plants used by Tetun ethnic people in West Timor Indonesia and evaluate the antiplasmodial activity and phytochemicals of several plants that are widely used as oral medicine.

Materials And Methods: A field study to document antimalarial plants followed by laboratory works to test antiplasmodial activity and identify the phytochemical constituents of some selected plants extract were applied. The inhibitory potency of ethanolic extracts of wood, roots of , , and , whole plant of and , stem barks of , , and , and leaves of on the 3D7 strain were tested.

The Effect of Antler Deer Extracts from East Kalimantan in Bone Turnover Cell Models.

Objectives: Osteoporosis is a condition characterized by skeletal degradation of osseous tissue resulting in an escalated chance of broken bones. Traditionally, horn from East Kalimantan is used to treat many diseases, including conditions associated with bone turnover. The aim of the present research was to analyze the effects of 70% ethanol and aqueous extracts of antler's horn from East Kalimantan on nitric oxide inhibition, osteoblast differentiation, and mineralization related to bone turnover.

Ferulic Acid Prevents Angiogenesis Through Cyclooxygenase-2 and Vascular Endothelial Growth Factor in the Chick Embryo Chorioallantoic Membrane Model.

Objectives: This study was designed to verify the antiangiogenic activity of ferulic acid (FA) and its potency to inhibit cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) expression in the chorioallantoic membrane (CAM) model. Moreover, we verified its mechanism of action by docking the molecule on COX-2, tyrosine kinase, and VEGF-2 proteins .

Materials And Methods: An antiangiogenesis assay of FA at doses of 30, 60, and 90 μg was performed using the CAM of chicken eggs that were 9 days old and stimulated by 60 ng of basic fibroblast growth factor.

Analysis of effectiveness and drug related problems of pain reliever for knee osteoarthritis: weighing clinical risk and benefit.

Background Osteoarthritis (OA) is a chronic degenerative joint disease, characterized by physiological disorders, such as cartilage degradation, bone remodeling, osteophyte formation, and joint inflammation, which results in pain. Several studies have reported problems with the use of pain medications in OA, such as the use of a combination of many drugs and their long-term use. Therefore, this study was designed to evaluate the use of pain medications in OA patients.

The contemporary role and potential of pharmacist contribution for community health using social media.

Background Social media (SM) is everywhere, and it affects all aspects of life, including health care. This study aimed to identify pharmacist activity in SM and explore the potential for pharmacist contributions using SM. Methods Focus group discussions (FGDs) were conducted in four cities in Indonesia.