460 results match your criteria: "Air Force Institute of Technology[Affiliation]"

Recent alcohol intake impacts microbiota in adult burn patients.

Alcohol

August 2024

Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC) for Veteran Suicide Prevention, Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), Aurora, CO, USA; Department of Surgery, Division of GI, Trauma, and Endocrine Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Graduate Program in Molecular Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Veterans Health Administration, Eastern Colorado Health Care System, Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), Aurora, CO, USA; Alcohol Research Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:

Alcohol use is associated with an increased incidence of negative health outcomes in burn patients due to biological mechanisms that include a dysregulated inflammatory response and increased intestinal permeability. This study used phosphatidylethanol (PEth) in blood, a direct biomarker of recent alcohol use, to investigate associations between a recent history of alcohol use and the fecal microbiota, short chain fatty acids, and inflammatory markers in the first week after a burn injury for nineteen participants. Burn patients were grouped according to PEth levels of low or high and differences in the overall fecal microbial community were observed between these cohorts.

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Article Synopsis
  • REBOA is a medical procedure used in emergencies to help control bleeding in seriously injured people, especially in trauma cases.
  • This study looked at 17 cases where REBOA was used in military settings between 2017 and 2019.
  • Most of the injured patients survived after getting treatment, with many having serious injuries mostly in the abdomen and limbs.
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Chitosan has gained considerable recognition within the field of medical applications due to its exceptional biocompatibility and diverse range of properties. Nevertheless, prior reviews have primarily focused on its applications, offering limited insights into its source materials. Hence, there arises a compelling need for a comprehensive review that encompasses the entire chitin and chitosan life cycle: from the source of chitin and chitosan, extraction methods, and specific medical applications, to the various techniques employed in evaluating chitosan's properties.

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Injuries and subclinical effects from exposure to blasts are of significant concern in military operational settings, including tactical training, and are associated with self-reported concussion-like symptomology and physiological changes such as increased intestinal permeability (IP), which was investigated in this study. Time-series gene expression and IP biomarker data were generated from "breachers" exposed to controlled, low-level explosive blast during training. Samples from 30 male participants at pre-, post-, and follow-up blast exposure the next day were assayed via RNA-seq and ELISA.

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Injury related to blast exposure dramatically rose during post-911 era military conflicts in Iraq and Afghanistan. Mild traumatic brain injury (mTBI) is among the most common injuries following blast, an exposure that may not result in a definitive physiologic marker (e.g.

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Characterizing as a surrogate for wastewater treatment studies and bioaerosol emissions.

Environ Sci (Camb)

November 2023

Department of Systems Engineering and Management, Engineering Management Program, Air Force Institute of Technology, 2950 Hobson Way, Wright-Patterson AFB, OH, USA.

This study characterized (BG) as a Sterne (BAS) surrogate for wastewater treatment-related studies of UV inactivation, adsorption onto powdered activated carbon (PAC), and bioaerosol emission. The inactivation of BG was faster than that of BAS in DI water (pseudo first-order rate constants of 0.065 and 0.

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How individuals' opinions influence society's resistance to epidemics: an agent-based model approach.

BMC Public Health

March 2024

School of Industrial Engineering, Purdue University, Grant St, West Lafayette, 47907, IN, USA.

Background: Protecting public health from infectious diseases often relies on the cooperation of citizens, especially when self-care interventions are the only viable tools for disease mitigation. Accordingly, social aspects related to public opinion have been studied in the context of the recent COVID-19 pandemic. However, a comprehensive understanding of the effects of opinion-related factors on disease spread still requires further exploration.

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Optically Transparent Lead Halide Perovskite Polycrystalline Ceramics.

ACS Appl Mater Interfaces

March 2024

Air Force Research Laboratory, Materials and Manufacturing Directorate, Wright-Patterson Air Force Base, Ohio 45433, United States.

We utilize room-temperature uniaxial pressing at applied loads achievable with low-cost, laboratory-scale presses to fabricate freestanding CHNHPbX (X = Br, Cl) polycrystalline ceramics with millimeter thicknesses and optical transparency up to ∼70% in the infrared. As-fabricated perovskite ceramics can be produced with desirable form factors (i.e.

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This paper presents the results of research on the impact of graphene paper on selected bacterial strains. Graphene oxide, from which graphene paper is made, has mainly bacteriostatic properties. Therefore, the main goal of this research was to determine the possibility of using graphene paper as a carrier of a medicinal substance.

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Purpose Of Review: Inhalation of airborne pollutants in the natural and built environment is ubiquitous; yet, exposures are different across a lifespan and unique to individuals. Here, we reviewed the connections between mental health outcomes from airborne pollutant exposures, the biological inflammatory mechanisms, and provide future directions for researchers and policy makers. The current state of knowledge is discussed on associations between mental health outcomes and Clean Air Act criteria pollutants, traffic-related air pollutants, pesticides, heavy metals, jet fuel, and burn pits.

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The aim of this article is to experimentally determine the role of the environment, consisting of a base oil (PAO), carbon nanomaterials, and optional other additives, as well as the kind of metal in contact with the lubrication film, in the stimulation of zinc dialkyldithiophosphate (ZDDP) additives' effectiveness during protective film formation. This paper focuses on the role of carbon nanostructures in energy transportation and conversion during tribological processes. An antistatic additive (ASA) (not used in lubricating oils) for jet fuels was added to disturb the process of energy conduction (electric charges) through the lubricant film and thus determine how this disturbance affects the kinetics of the ZDDP triboreaction and, consequently, the linear wear.

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Optofluidic passive parity-time-symmetric systems.

R Soc Open Sci

January 2024

Department of Electrical and Computer Engineering, Air Force Institute of Technology, Wright-Patterson Air Force Base, OH 45433, USA.

This research introduces a novel methodology of harnessing liquids to facilitate the realization of parity-time ()-symmetric optical waveguides on highly integrated microscale platforms. Additionally, we propose a realistic and detailed fabrication process flow, demonstrating the practical feasibility of fabricating our optofluidic system, thereby bridging the gap between theoretical design and actual implementation. Extensive research has been conducted over the past two decades on -symmetric systems across various fields, given their potential to foster a new generation of compact, power-efficient sensors and signal processors with enhanced performance.

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Longitudinal Influence of Prescribed Antidepressants on Fecal and Oral Microbiomes Among Veterans With Major Depressive Disorder.

J Neuropsychiatry Clin Neurosci

April 2024

Veterans Affairs Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, Colo. (Hoisington, Stearns-Yoder, Stamper, Simonetti, Brenner); Military and Veteran Microbiome Consortium for Research and Education, Aurora, Colo. (Hoisington, Stearns-Yoder, Stamper, Brenner); Department of Physical Medicine and Rehabilitation (Hoisington, Stearns-Yoder, Stamper, Brenner), Division of Hospital Medicine, Department of Medicine (Simonetti), and Departments of Psychiatry and Neurology (Brenner), University of Colorado Anschutz Medical Campus, Aurora, Colo.; Department of Systems Engineering and Management, Air Force Institute of Technology, Wright-Patterson Air Force Base, Ohio (Hoisington); Veterans Integrated Services Network 4 MIRECC, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia (Oslin); Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Oslin).

Objective: The purpose of this study was to evaluate the influence of a new course of antidepressant monotherapy on gut and oral microbiomes and the relationship to depressive symptoms.

Methods: Longitudinal microbiome samples obtained from 10 U.S.

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Association of homelessness and diet on the gut microbiome: a United States-Veteran Microbiome Project (US-VMP) study.

mSystems

January 2024

Department of Veterans Affairs, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC) for Suicide Prevention, Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), Aurora, Colorado, USA.

Military veterans account for 8% of homeless individuals living in the United States. To highlight associations between history of homelessness and the gut microbiome, we compared the gut microbiome of veterans who reported having a previous experience of homelessness to those from individuals who reported never having experienced a period of homelessness. Moreover, we examined the impact of the cumulative exposure of prior and current homelessness to understand possible associations between these experiences and the gut microbiome.

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Introduction: Research suggests women are more likely to fail their military physical fitness assessment in the immediate postpartum period than in the prenatal period. In 2015, the United States Air Force physical fitness postpartum testing dwell time increased from 6 months to 12 months postpartum. The primary aim of this study was to assess if Air Force active duty women's physical readiness, as indicated by individual physical fitness test results, was impacted by this change.

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While many studies of intestinal permeability (IP) are focused on those with gastrointestinal (GI) disorders, there is a rising trend to analyze IP among individuals with mental health conditions including posttraumatic stress disorder (PTSD) with and without diagnosed GI conditions. This interest stems from the association between gut dysbiosis and chronic inflammation, which are mechanisms linked to stress-related somatic and mental health conditions. Efforts to date have resulted in the exploration of non-invasive and feasible measures to identify an IP biomarker that could also serve as a treatment target.

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Hydroxyl radical-driven transformations of bisphenol A and 2,4-dinitroanisole: Experimental and computational analysis.

Water Environ Res

November 2023

Environmental Engineering and Science Program, Department of Systems Engineering and Management, Air Force Institute of Technology, Wright-Patterson AFB, Ohio, USA.

This study used experimental and computational analysis to investigate the advanced oxidation of bisphenol A (BPA) and 2,4-dinitroanisole (DNAN). The pseudo first-order reaction rate constants depended on the molar peroxide ratio and were between 0.13 and 0.

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Machine learning algorithms were used to analyze the odds and predictors of complications of thyroid damage after radiation therapy in patients with head and neck cancer. This study used decision tree (DT), random forest (RF), and support vector machine (SVM) algorithms to evaluate predictors for the data of 137 head and neck cancer patients. Candidate factors included gender, age, thyroid volume, minimum dose, average dose, maximum dose, number of treatments, and relative volume of the organ receiving X dose (X: 10, 20, 30, 40, 50, 60 Gy).

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Perturbing finite temperature multicomponent DFT 1D Kohn-Sham systems: Peierls gap & Kohn anomaly.

J Phys Condens Matter

November 2023

Department of Physics, Air Force Institute of Technology, 2950 Hobson Way, Wright-Patterson AFB, OH 45433, United States of America.

One of the greatest challenges when designing new technologies that make use of non-trivial quantum materials is the difficulty associated with predicting material-specific properties, such as critical temperature, gap parameter, etc. There is naturally a great amount of interest in these types of condensed matter systems because of their application to quantum sensing, quantum electronics, and quantum computation; however, they are exceedingly difficult to address from first principles because of the famous many-body problem. For this reason, a full electron-nuclear quantum calculation will likely remain completely out of reach for the foreseeable future.

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Climate change and air pollution are two interconnected global challenges that have profound impacts on human health. In Africa, a continent known for its rich biodiversity and diverse ecosystems, the adverse effects of climate change and air pollution are particularly concerning. This review study examines the implications of air pollution and climate change for human health and well-being in Africa.

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Article Synopsis
  • Social and economic inequalities can really affect people's health, especially by changing the tiny bacteria in our guts that help us stay healthy.
  • Living in a "food desert," where there isn’t enough healthy food, can make this problem worse and also hurt mental health.
  • More research is needed to understand how these inequalities, gut health, and mental health are connected over a person's lifetime.
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