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Dextran-based Nanocarriers for Delivery of Bioactives.

Curr Pharm Des

November 2017

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University. African organization Unity Street, Cairo, Egypt.

Background: Dextran (DX) is a natural polysaccharide produced in the laboratory by fermentation of sucrose under the effect of the enzyme DX sucrase (1,6-α-D-glucan-α- glucosyltransferase). After harvesting and purification DX is subjected to cracking and separation to obtain the desired molecular weight.

Methods: The hydroxyl groups present in DX offer many sites for derivatization allowing the production of functionalized glycoconjugates biocompatible compound.

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