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Article Synopsis
  • The study focused on a diffusion chamber (DC) system combined with a scaffold to culture cells in vivo, reducing the risk of contamination.
  • The experiment involved using a PLGA sponge and rat bone marrow cells, which were placed inside a DC and implanted in the abdominal cavities of rats.
  • After four weeks, the results showed the formation of fibrous and calcified tissue around the sponge, demonstrating that the PLGA sponge effectively supported three-dimensional tissue formation in vivo with minimal need for special technologies post-grafting.
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