Exploring the Impact of Interferon-Gamma Single Nucleotide Polymorphisms on HTLV-1 Infection: Unraveling Genetic Influences in Viral Pathogenesis.

Human T-lymphotropic virus-1 (HTLV-1) induces neoplastic adult T-cell leukemia/lymphoma (ATLL) and neurological HTLV-1 associated myelopathy (HAM) in approximately 3%-5% of infected individuals. The precise factors that facilitate disease manifestation are still unknown; interaction between the virus and the host's immune response is key. Cytokines regulates physiological activities and their dysregulation may initiate the pathogenesis of various malignant and infectious diseases.

EFFECT OF ELECTRONIC SHORT MESSAGE SERVICE REMINDERS ON MEDICATION ADHERENCE AMONG HYPERTENSIVE PATIENTS IN KATSINA STATE: A QUASIEXPERIMENTAL STUDY.

Introduction: Globally, hypertension is considered a public health problem affecting over 1.3 billion individuals of which 60% need reminders to take medication to achieve adherence, optimal blood pressure and avert complications. Literature shows electronic short message reminders (eSMS) improved medication adherence.

Retraction Note: Flavonoid fractions of diosmin and hesperidin mitigate lead acetate-induced biochemical, oxidative stress, and histopathological alterations in Wistar rats.

[This retracts the article DOI: 10.1007/s43188-020-00084-9.].

Insights into micro-and nano-zero valent iron materials: synthesis methods and multifaceted applications.

The growing threat of environmental pollution to global environmental health necessitates a focus on the search for sustainable wastewater remediation materials coupled with innovative remediation strategies. Nano and micro zero-valent iron materials have attracted substantial researchers' attention due to their distinct physiochemical properties. This review article delves into novel micro- and nano-zero valent iron (ZVI) materials, analysing their synthesis methods, and exploring their multifaceted potential as a powerful tool for environmental remediation.

Chemosuppressive Effects of Kolaviron on 7,12-Dimethylbenzanthracene-Induced Mammary Lesions are Associated with Changes in Levels of Estrogen Receptor-α, CYP 1A1, Proinflammatory Cytokines, and Alterations to Metabolic Pathways Implicated in Mammary Carcinogenesis.

is a medicinal food commonly consumed in Sub-Sahara Africa, for which Kolaviron (KV) is the active portion. As a follow-up to our earlier chemopreventive studies, we investigated the chemotherapeutic effects of KV on experimentally induced mammary carcinogenesis in female Wistar rats. Mammary carcinogenesis was induced using 80 mg/kg of 7,12-dimethylbenzanthracene (DMBA) administered by oral gavage.

Effects of dietary Silybum marianum powder on growth performance, egg and carcass characteristics, immune response, intestinal microbial population, haemato-biochemical parameters and sensory meat quality of laying quails.

The study aimed to assess the effects of different dietary Silybum marianum (SM, milk thistle) powder levels on growth performance, productivity, immunity, small intestine, haemato-biochemical parameters, meat quality, and egg and carcass characteristics of laying quails. The experimental subjects consisted of one hundred and eight 43-day-old quails divided into 3 treatments (0, 0.75, and 1.

Home-based care models for patients with terminal illnesses in low and middle-income countries: A systematic review of randomized and quasi-experimental studies.

Background: With the increasing lifespan of people and the transition from communicable to non-communicable diseases across the globe, there is an increasing number of people with terminal illnesses requiring home-based care in Low- and Middle-Income Countries (LMICs).

Aim: This systematic review evaluated home-based care models for patients with terminal illnesses in LMICs. The primary outcomes measured are quality of life (QoL), adherence to treatment, fatigue, bimanual and related activities.

Incidence and Determinants of Catheter-Related Bladder Spasms Following Transurethral Resection of the Prostate; A Prospective Review of 80 Cases.

Background: Bladder spasms due to involuntary contraction of the bladder occur frequently following Transurethral resection of the prostate (TURP). They may be aggravated by the presence of a catheter, blood clots, preoperative overactive bladder, or preoperative ingestion of bladder stimulants like caffeine. These bladder spams are painful, associated with peri-catheter leakage of urine, increased post-operative bleeding, and often refractory to postoperative analgesia.

Patient Satisfaction with Care and Its Predictors in a Secondary Hospital in Kaduna State, North-western Nigeria.

Background: Satisfied patients adhere more to counselling, prescribed treatment and referrals. Few studies reveal the sub-scales of satisfaction and predictors of satisfaction in north-western Nigeria.

Objectives: To determine patients' overall satisfaction with healthcare provision and their predictors at a secondary hospital in Kaduna metropolis, Kaduna State, North-Western Nigeria.

Dataset on a reliability generalization meta-analysis of the Oxford COVID-19 vaccine hesitancy scale.

The Oxford COVID-19 Vaccine Hesitancy Scale is a 7-item psychometric scale developed by Freeman and colleagues a year after detecting the first case of the disease in 2019. The scale assesses people's thoughts, feelings, and behavior toward COVID-19 vaccines. A comprehensive search of major electronic databases, including Scopus, Clarivate Analytics, and PubMed, was conducted to extract eligible articles for inclusion in this meta-analysis.

Effect of Antenatal Corticosteroids in Late Preterm Delivery on Neonatal Respiratory Morbidity: A Randomized Controlled Trial.

Background: The use of antenatal corticosteroids beyond 34 weeks of gestation to prevent certain neonatal complications remains a debate. This study sought to determine the effect of the use of antenatal corticosteroids in late preterm delivery on neonatal morbidity.

Methodology: It was a randomized double-blind placebo and active-controlled multi-arm trial.

Humanitarian crisis amid the military coup in Niger republic; what went wrong?

Introduction: A humanitarian crisis means any event or series of events that are harmful to the health or security of the general population. The Niger Republic is currently facing a serious crisis amid the military coup of July 26, 2023. We fear that if nothing is done about it quickly, there could be a civil war in Niger and other neighboring countries.

Ameliorative Effect of Against Dinitrophenylhydrazine Induced Hyperbilirubinemia in Wistar Albino Rats.

Background: popularly known as gawo in Hausa, is traditionally used to treat jaundice in Zuru emirate of Kebbi State. Herein, the ameliorative effect of against 2.4-dinitrophenylhydrazine-induced hyperbilirubinemia in Wistar albino rats was investigated.

Spectral-like conjugate gradient methods with sufficient descent property for vector optimization.

Several conjugate gradient (CG) parameters resulted in promising methods for optimization problems. However, it turns out that some of these parameters, for example, 'PRP,' 'HS,' and 'DL,' do not guarantee sufficient descent of the search direction. In this work, we introduce new spectral-like CG methods that achieve sufficient descent property independently of any line search (LSE) and for arbitrary nonnegative CG parameters.

Advancements and progress in juvenile idiopathic arthritis: A Review of pathophysiology and treatment.

Juvenile idiopathic arthritis (JIA) is a chronic clinical condition characterized by arthritic features in children under the age of 16, with at least 6 weeks of active symptoms. The etiology of JIA remains unknown, and it is associated with prolonged synovial inflammation and structural joint damage influenced by environmental and genetic factors. This review aims to enhance the understanding of JIA by comprehensively analyzing relevant literature.

Antipsychotics-related hyperprolactinaemia among patients with schizophrenia in Maiduguri.

Background: Hyperprolactinaemia among patients on antipsychotic medications is generally overlooked due to lack of outwardly visible symptoms, patient resistance to reporting because the symptoms are perceived as shameful, or to clinician's insufficient knowledge.

Aim: The study aimed to evaluate the patterns and correlates of hyperprolactinemia among patients with schizophrenia on antipsychotic medications.

Setting: The study was conducted in a psychiatric facility in Maiduguri, Northeastern Nigeria.

Ligand based-design of potential schistosomiasis inhibitors through QSAR, homology modeling, molecular dynamics, pharmacokinetics, and DFT studies.

Objectives: Schistosomiasis, a neglected tropical disease, is a leading cause of mortality in affected geographic areas. Currently, because no vaccine for schistosomiasis is available, control measures rely on widespread administration of the drug praziquantel (PZQ). The mass administration of PZQ has prompted concerns regarding the emergence of drug resistance.

Urinary schistosomiasis and anemia among school-aged children from southwestern Nigeria.

Schistosomiasis and anemia, are one of the leading global public health problem among children between age 5 and 14 years in marginalized settings. In this study, we provide prevalence and intensity data for both conditions in three southwestern states of Nigeria, where such are lacking. Epidemiological assessment involving parasitological analysis of urine and blood samples was conducted among 1783 consenting school-aged children in Ondo, Osun, Ekiti States of Nigeria.

First report of co-infections of Marek's disease virus and chicken infectious anaemia virus in poultry flocks in Nigeria.

Marek's disease (MD) and chicken infectious anaemia (CIA) are viral immunosuppressive diseases of poultry caused by the MD virus (MDV) and CIA virus (CIAV) respectively. Despite vaccination against MD, the incidence of the disease in vaccinated poultry flocks in Nigeria persists. However, underlying factors like co-infection with CIAV have not been investigated in the country.

Serological evidence of Newcastle disease virus antibodies in wild birds in Zaria, Kaduna State, Nigeria.

Wild birds have been reported to be reservoirs of viral diseases of poultry, and play an epidemiological role in their maintenance and spread. A serological survey was undertaken to determine the evidence of Newcastle disease virus (NDV) antibodies in wild birds in Zaria Kaduna State, Nigeria. A total of 150 apparently healthy wild birds comprising 30 each laughing dove, speckled pigeons, cattle egrets, village weavers and African silver bills were sampled.

Selecting the optimal gridded climate dataset for Nigeria using advanced time series similarity algorithms.

Choosing a suitable gridded climate dataset is a significant challenge in hydro-climatic research, particularly in areas lacking long-term, reliable, and dense records. This study used the most common method (Perkins skill score (PSS)) with two advanced time series similarity algorithms, short time series distance (STS), and cross-correlation distance (CCD), for the first time to evaluate, compare, and rank five gridded climate datasets, namely, Climate Research Unit (CRU), TERRA Climate (TERRA), Climate Prediction Center (CPC), European Reanalysis V.5 (ERA5), and Climatologies at high resolution for Earth's land surface areas (CHELSA), according to their ability to replicate the in situ rainfall and temperature data in Nigeria.