555 results match your criteria: "Ageing Research Centre[Affiliation]"

What do coaches want? Exploring the preferences of youth rugby union coaches for education in the implementation of injury prevention programmes.

Phys Ther Sport

December 2024

Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland; Sport and Human Performance Research Centre, University of Limerick, Limerick, Ireland; Health Research Institute, University of Limerick, Limerick, Ireland; Lero, Irish Software Research Centre, University of Limerick, Ireland. Electronic address: https://twitter.com/IanCKenny.

Objective: To explore youth Rugby Union coaches' preferences for education and support in the implementation of injury prevention programmes (IPPs).

Methods: Twelve Rugby Union coaches involved with youth teams participated in five online focus groups. Conventional content analysis was used to determine preferences initially from transcripts, and thereafter main categories, generic categories and sub-categories.

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Article Synopsis
  • The study aimed to validate the Global Leadership Initiative on Malnutrition (GLIM) criteria for diagnosing malnutrition in hospitalized patients before it can be widely used.
  • Researchers assessed the GLIM criteria's content validity, reliability, and predictive validity by analyzing outcomes like hospital mortality and readmission rates in a sample of 332 hospitalized adults.
  • Results showed that the GLIM criteria accurately identified malnourished patients and were reliable, indicating a significant association with increased hospital stays and mortality risks, thereby supporting its use in clinical settings.
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The use of sequential multiple assignment randomized trials (SMARTs) in physical activity interventions: a systematic review.

BMC Med Res Methodol

December 2024

School of Allied Health, Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland.

Background: Physical activity (PA) is often the cornerstone in risk-reduction interventions for the prevention and treatment of many chronic health conditions. PA interventions are inherently multi-dimensional and complex in nature. Thus, study designs used in the evaluation of PA interventions must be adaptive to intervention components and individual capacities.

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Introduction: Loneliness and physical inactivity are issues that affect both young people and older adults. This can have negative health outcomes and well as high costs on health services. Physical activity can positively influence both physical and psychosocial health outcomes, however enjoyment is necessary for adherence.

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Objective: The objective was to identify the priorities of individuals with musculoskeletal shoulder pain and their health care providers (HCPs) that are perceived to foster multi-stakeholder adherence to evidence-based recommendations.

Methods: The study used a mixed methods design, informed by concept mapping. Patients with shoulder pain (ie, ≥6 weeks) and HCPs involved in their care (recruited via social media, email, etc.

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Chromium has been recognized for its beneficial effects on inflammation reduction; therefore, we conducted a systematic review and meta-analysis to find the effect of chromium supplementation on serum levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) in subjects aged 18 years and older. Related articles were identified by searching databases such as the Cochrane Library, ClinicalTrials.gov, ISI Web of Science, Scopus, and PubMed up until Agust 2024.

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Background: Plasma osteopontin (pOPN) is a promising aging-related biomarker among individuals with and without kidney disease. The interaction between sex, pOPN levels, and global and cardiorenal outcomes among older individuals was not previously evaluated.

Methods: In this study we investigated the association of pOPN with 24-month global mortality, major cardiovascular events (MACEs), MACEs + cardiovascular (CV) mortality, and renal decline among older individuals; we also evaluated whether sex modified observed associations.

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An Early Supported Discharge (ESD) Model of Care for Older Adults Admitted to Hospital: A Descriptive Cohort Study.

Clin Interv Aging

December 2024

School of Allied Health, Faculty of Education and Health Sciences, Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland.

Background: Early supported discharge (ESD) facilitates early discharge from acute hospitals with continued rehabilitation in the home environment from a multi-disciplinary team at the same intensity as would be received in the inpatient setting. Emerging evidence suggests it can have a positive impact on the care of older adults on discharge from the acute hospital setting to home. This study aims to characterize an inreach model of ESD for older adults discharged from four hospitals in the Mid-West of Ireland and describe its impact on clinical and process outcomes at 30 and 180 days.

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Background: Assessing liver health and its determinants in the elderly is crucial. Lifestyle factors, including nutrition and exercise, may influence liver function. This study aimed to investigate the association between macronutrients and energy intake with serum levels of aminotransferases in elderly Iranian athletes and non-athletes.

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Article Synopsis
  • Musculoskeletal pain is a major public health issue in Europe, and how people search for online health information plays a crucial role in managing their health.
  • The study investigates the online information-seeking behavior of individuals in five European countries by using a two-phase approach that includes keyword extraction, panel refinement, and categorizing online sources.
  • The findings aim to enhance digital health literacy and improve resources for managing musculoskeletal pain, ultimately leading to better health outcomes.
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Objectives: To explore the content (subjective questions, objective tools and outcome measures) and discuss the nature (qualitative elements and wider considerations) of the athlete pain assessment by facilitating shared understandings of athletes and sports physiotherapists.

Design: Qualitative research using a hermeneutic phenomenological approach.

Methods: We carried out focus groups comprising a deliberate criterion sample using a constructivist perspective.

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Frailty screening with comprehensive geriatrician-led multidisciplinary assessment for older adults during emergency hospital attendance in Ireland (SOLAR): a randomised controlled trial.

Lancet Healthy Longev

November 2024

School of Allied Health, Faculty of Education and Health Sciences, Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland; Ageing Research Centre, University of Limerick, Limerick, Ireland.

Background: Multidisciplinary comprehensive geriatric assessment (CGA) improves outcomes in hospitalised older adults but there is limited evidence on its effectiveness in the emergency department. We aimed to assess the benefits of CGA in the emergency department for older adults living with frailty.

Methods: In this randomised controlled trial, we enrolled older adults (≥75 years) who presented to the emergency department with medical complaints at University Hospital Limerick (Limerick, Ireland).

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Purpose: In this study, a comprehensive analysis of costs of chronic kidney disease (CKD) was performed, to understand factors associated with the economic burden of the disease in a multicentre international framework.

Methods: The impact on costs of demographics, socio-economics, clinical, and functional variables was tested in 2204 subjects aged 75 years or more attending outpatient clinics in Europe using a multicentre 2-year prospective cohort study. By means of collected resources consumption and unit cost data a comprehensive cost database was built and then investigated using multilevel regression modeling.

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  • The study aimed to explore the effectiveness of intergenerational cafés in promoting learning between older adults and student nurses, identifying both barriers and facilitators in the process.
  • Using a framework for implementation research, data was gathered through surveys and focus groups from participants, revealing key insights about the café experiences.
  • Results showed that clear organization in topics helped engagement, while technical issues were barriers; overall, participants found the cafés beneficial for mutual learning and fostering intergenerational connections.
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  • Hypomagnesemia (low magnesium) and hypocalcemia (low calcium) are linked to cognitive decline in older adults, but previous research mainly focused on diet instead of actual nutrient levels.
  • The study analyzed data from 1,220 hospitalized patients aged 60+, categorizing them based on their magnesium and calcium levels to see how these deficiencies affect cognitive performance, measured by tests like the MMSE and CDT.
  • Results showed that both deficiencies, along with factors like age, sex, and chronic conditions, significantly lowered cognitive performance, highlighting the importance of monitoring these nutrient levels in seniors.
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Background: Older adults often experience adverse health outcomes including malnutrition following discharge from emergency departments (ED). Discharge to community care is a transitionary time where nutritional vulnerability could be mitigated with the instigation of targeted nutrition care pathways in ED settings.

Aims And Objectives: This scoping review aimed to establish and describe the level of nutrition care provided to older adults admitted and subsequently discharged from EDs.

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Purpose: Statin therapy is widely used for the management of dyslipidemia and the prevention of cardiovascular diseases (CVDs). However, there is a growing concern about its potential effects on bone metabolism markers and mineral density. The aim of this systematic review and meta-analysis was to investigate the effect of statin therapy on these parameters.

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Objectives: To explore the priorities and directions of athlete upper and lower limb pain assessment by facilitating shared understandings of athletes and sport physiotherapists.

Design: Qualitative research using a hermeneutic phenomenological approach.

Methods: We carried out focus groups comprising a deliberate criterion sample using a constructivist perspective.

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Background: In emergency care settings, screening for disease or risk factors for poor health outcomes among older adults can identify those in need of specialist and early intervention. The aim of this study was to identify barriers and facilitators to implementing older person-centred screening in emergency care settings in the Mid-West of Ireland.

Methods: This study employed a qualitative descriptive design underpinned by the theoretical domains framework (TDF).

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'Excellent for mind,body and spirit': Participant, facilitator, and community stakeholder experiences of Music and Movement for Health.

Complement Ther Clin Pract

November 2024

School of Allied Health, University of Limerick, Limerick, Ireland; Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland; Division of Physiotherapy, Department of Health and Rehabilitation Sciences, Stellenbosch University, Cape Town, South Africa. Electronic address:

Background And Purpose: Arts-based interventions are an emerging area of interest in health research for older adults. Music and Movement for Health (MMH) is one such systematically developed interdisciplinary arts-based intervention designed to enhance health and wellbeing of older adults. The objective of this qualitative study was to explore the opinions and experiences of participants, facilitators, and community stakeholders of the MMH intervention.

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Background: The two-step Global Leadership Initiative on Malnutrition (GLIM) approach was recently introduced to malnutrition diagnosis in a hospital setting. This study compares the diagnostic performance of this approach that uses the Nutritional Risk Screening-2002 (NRS-2002) as a screening tool and the direct application of GLIM malnutrition diagnostic criteria in hospitalized patients.

Methods: This cross-sectional study involved 290 adult and older adult patients who were hospitalized.

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Article Synopsis
  • The study investigated the safety and effects of curcumin-coated silver nanoparticles (CUR-Ag-NPs) on pubertal male Wistar rats exposed to the pesticide chlorpyrifos (CPF).
  • Forty-two rats were divided into seven treatment groups and monitored over 30 days for impacts on liver and kidney health.
  • Results showed no significant changes in serum enzyme levels, but both liver and kidney tissues exhibited signs of inflammation and degenerative changes, indicating that CUR-Ag-NPs did not demonstrate safety or therapeutic efficacy at the tested doses.
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  • Oxidative stress occurs when there's an imbalance between harmful reactive species and the body's ability to eliminate them, playing a role in various disorders, including epilepsy, which is marked by unpredictable seizures.
  • The protein Nrf2, known for its role in regulating the response to oxidative stress, activates detoxifying genes when it escapes the Keap1 protein and moves to the nucleus.
  • Research suggests that activating Nrf2 through certain compounds, such as Berberis alkaloids and pentoxifylline, shows promise in treating epilepsy by mitigating oxidative stress.
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