158 results match your criteria: "Ageing Futures Institute[Affiliation]"

Wearable Technology in Mobility and Falls Health Care: Finding Consensus on Their Clinical Utility and Identifying a Roadmap to Actual Use.

J Geriatr Phys Ther

January 2025

Neuroscience Research Australia, Randwick, New South Wales, Australia (Drs Ambrens and van Schooten and Professors Delbaere and Close).

Background: Despite the promise wearable technology offers through detailed insight into mobility and fall risk, timely identification of high risk, assessment of risk severity, evaluation of clinical interventions, and potential to redefine the assessment of behaviours which influence health, they are not routinely used in clinical practice.

Objective: Establish consensus on how wearable technology can be applied to support clinical care for people aged 50 and over experiencing changes to mobility and/or who are at increased risk of falling.

Methods: A Delphi study was conducted among 17 hospital-based health professionals.

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Objectives: This study examined the association between polypharmacy and incident disability across the dietary variety score (DVS) strata among community-dwelling older adults.

Study Design: A prospective cohort study with community-dwelling adults aged ≥65 in Aichi, Japan.

Main Outcome Measures: Polypharmacy was defined as ≥5 concomitant prescription drugs per day.

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Background: Fall injuries resulting from trips are a major health concern. Virtual reality (VR) offers an effective way of training obstacle avoidance while walking due to its ability to provide safe and meaningful real-time feedback during rehabilitation. This proof-of-concept study examined the benefit of providing physical feedback during obstacle avoidance gait training using VR.

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Culturally safe and ethical biomarker and genomic research with Indigenous peoples-a scoping review.

BMC Glob Public Health

October 2024

Department of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Royal Melbourne Hospital, Melbourne, Victoria, Australia, Victoria, Melbourne, Australia.

Background: Indigenous peoples globally continue to be underrepresented in biomarker, genomic, and biobanking research. The aim of this study was to identify core components of culturally safe and ethical biomarker and genomic research with Indigenous peoples in Australia, Aotearoa/New Zealand, Canada and the USA.

Methods: A scoping review with a systematic search strategy was conducted utilising electronic databases MEDLINE, EMBASE, PsychINFO, CINAHL and Global Health.

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Impact of Childhood Adversity on Late-Life Cognition in Older Puerto Rican Adults.

J Gerontol B Psychol Sci Soc Sci

December 2024

Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ, USA.

Objectives: This study examined the association between childhood adversity and late-life cognitive outcomes among older Puerto Rican adults.

Methods: Data were from the PREHCO study, a population-based cohort of 3,713 older Puerto Rican adults (mean age 72.5 years; 60% female).

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Background: Aboriginal and Torres Strait Islander peoples' have sustained their cultural practices for over 60,000 years which fundamentally impacts their health and wellbeing. Recent literature emphasizes cultural connection as a contributor to good public health, yet the mechanisms through which cultural engagement promotes health and wellbeing remain underexplored. This study investigates the health and wellbeing outcomes associated with Aboriginal peoples' participation in cultural camps in New South Wales (Australia), focusing on the role of cultural determinants of health.

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Unlabelled: Indigenous cultural health is an emerging field of research and reflects the unique connections Indigenous peoples have with their Country, culture, and knowledge systems. This narrative review explores the concept of cultural health focusing on the interplay between culture, health, and wellbeing within settler colonial contexts. The review is mostly focused on Australian research, despite its international scope.

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Article Synopsis
  • - A long-term study in Norway tracked 9,745 individuals for 30 years to explore how midlife depression and anxiety might influence the risk of developing dementia.
  • - The research found that individuals who later developed dementia showed higher rates of anxiety and depression throughout the study, with a notable increase especially in the years leading up to their dementia diagnosis.
  • - The results indicated that mixed anxiety and depressive symptoms were more prevalent in older individuals with dementia, suggesting a significant link between mental health issues in midlife and subsequent dementia risk across various types of dementia.
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Background: Vaginal aplasia or hypoplasia often requires the creation of a neovagina using vaginal dilation therapy, vaginoplasty surgery, or a combination of both. However, the absence of validated guidelines and the controversy surrounding vaginoplasty surgery have limited our understanding of the long-term outcomes and impact on quality of life and psychosexual functioning for women with a short or absent vagina. This study provides valuable insights into the Australian context, reflecting the treatment approaches and long-term psychosocial outcomes for this patient group.

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Objectives: Deterioration in vision is an important dementia risk factor yet few studies have examined objectively measured changes in visual acuity over time. Visual decline may also reduce social engagement, highlighting the need to examine visual changes in concert with broader social function.

Method: The relationship between change in visual acuity (logMAR) and cognitive decline was examined in 2,281 participants from the PATH study using hierarchical linear regression.

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Background: Current estimates of dementia and Alzheimer's disease incidence and prevalence are required to understand the health needs of the elderly.

Objective: We used two Australia cohort studies, administrative datasets, and data linkage techniques to estimate dementia rates in Australia.

Methods: The study used Australian Longitudinal Study on Women's Health and the Health in Men Cohort Study.

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Background: We aimed to develop risk tools for dementia, stroke, myocardial infarction (MI), and diabetes, for adults aged ≥ 65 years using shared risk factors.

Methods: Data were obtained from 10 population-based cohorts (N = 41,755) with median follow-up time (years) for dementia, stroke, MI, and diabetes of 6.2, 7.

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Around 55 million people worldwide live with dementia, and more are expected due to population ageing. We aimed to investigate associations between healthy diet and mild cognitive impairment and dementia in 1753 older adults aged 60-64 from the PATH (Personality and Total Health Through Life Cohort) study. Healthy diet was defined by the Mediterranean-DASH diet Intervention for Neurological Delay (MIND) and two dietary guideline quality scores (Dietary Guideline Index (DGI) and Index Diet Quality (IDQ)), which were calculated from baseline FFQ.

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Article Synopsis
  • * Most countries in the region lack specific national dementia plans and awareness campaigns, leading to inadequate resources for treatment and support.
  • * To address these issues, comprehensive national plans are necessary, focusing on improving dementia literacy, training caregivers, mobilizing resources, and enhancing research capabilities, while involving input from affected individuals and families.
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Article Synopsis
  • Changes in the brain from Alzheimer's and other age-related diseases can cause problems with thinking and behavior, even before serious symptoms appear.
  • The study looked at how a person's cognitive reserve (a mix of education and experiences) relates to mild behavioral issues.
  • Results showed that people with a higher cognitive reserve had better brain test scores and fewer behavior problems, which suggests that keeping mentally active might help both thinking and behavior as we get older.
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Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts.

JAMA Netw Open

October 2024

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, Australia.

Article Synopsis
  • Poststroke cognitive impairment is common, but the exact changes in cognitive function following a first stroke compared to pre-stroke levels are not fully understood.
  • The study aimed to track cognitive performance over time in stroke survivors versus individuals without strokes, using data from 14 international cohorts of older adults.
  • Results showed that incident stroke led to a significant immediate drop in overall cognitive skills and accelerated decline in cognitive abilities over time.
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Objectives: Interpersonal relevancy appraisals are a dynamic and understudied aspect of human social cognition. Despite their importance, there are no existing measures. This study developed and validated a new measure of self-perceived interpersonal threat, opportunity, and invisibility appraisals among a life-course sample of adults.

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The association between patient self-reported experiences with medication discharge counselling and hospital readmissions: A cross-sectional analysis of a population-based survey.

Res Social Adm Pharm

January 2025

The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, NSW, Australia; School of Population Health, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia; UNSW Ageing Futures Institute, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.

Objective: To investigate the association between patient-reported experiences with new medication discharge counselling and readmission to hospital or emergency department (ED) visits within 30 days of discharge.

Methods: A retrospective cross-sectional study of patient-reported experiences from 8715 patients who reported being prescribed a new medication at discharge from a public hospital. Completeness of medication counselling was assessed based on (i) explanation of medication purpose, (ii) explanation of medication side effects, (iii) patient involvement in decision to use medication, (iv) provision of contradictory information.

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Article Synopsis
  • The study focuses on understanding frailty among Aboriginal Australians, a group significantly affected by this health issue, highlighting the need for research that acknowledges their unique perspectives compared to Western frameworks.
  • Utilizing qualitative methods, specifically the Indigenous research technique of Yarning, the study engaged 22 Aboriginal adults aged 45+ to gather insights on their experiences and perceptions of frailty.
  • The research identified seven thematic areas related to frailty, emphasizing the importance of cultural, social, and psychological factors in managing frailty, ultimately indicating that culturally relevant assessments and community connection are crucial for better health outcomes.
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Introduction: Promising evidence is emerging for the procognitive, anti-inflammatory and neuroprotective properties of dietary flavonoids, particularly anthocyanins that provide red, purple and blue plant pigments.

Methods And Analysis: The 'Food for Thought' study is a multicentre, 6-month randomised, parallel 3-arm clinical trial. Its primary aim is to investigate whether anthocyanin consumption, either through diet or supplementation, can prevent memory loss progression and improve inflammatory and cardiovascular health in older adults at risk for dementia.

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Plant but not animal sourced nitrate intake is associated with lower dementia-related mortality in the Australian Diabetes, Obesity, and Lifestyle Study.

Front Nutr

August 2024

Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Royal Perth Hospital Research Foundation, Edith Cowan University, Perth, WA, Australia.

Introduction: Dietary nitrate is potentially beneficial for cardiovascular, cerebrovascular, and nervous systems due to its role as a nitric oxide (NO) precursor. Increased nitrate intake improves cardiovascular health and therefore could protect against dementia, given the cardiovascular-dementia link.

Objective: To investigate the association between source-dependent nitrate intake and dementia-related mortality.

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Neighbourhood environments and cognitive health in the longitudinal Personality and Total Health (PATH) through life study: A 12-year follow-up of older Australians.

Environ Int

September 2024

School of Psychology, University of New South Wales, Randwick, New South Wales, Australia; Neuroscience Research Australia (NeuRA), Sydney, Australia; UNSW Ageing Futures Institute, Sydney, Australia. Electronic address:

Background: Urban neighbourhood environments may impact older adults' cognitive health. However, longitudinal studies examining key environmental correlates of cognitive health are lacking. We estimated cross-sectional and longitudinal associations of neighbourhood built and natural environments and ambient air pollution with multiple cognitive health outcomes in Australian urban dwellers aged 60+ years.

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Article Synopsis
  • The study aims to enhance road safety among older drivers by evaluating three behavioral interventions: an online road-rules workshop, tailored driving feedback, and personalized driving lessons.
  • A randomized controlled trial will involve 198 urban drivers aged 65 and older, focusing on those identified as moderately unsafe through an on-road test.
  • The study, approved by the ethics committee at the University of New South Wales, seeks to contribute actionable insights to improve safety and influence health policies, with results shared in academic journals and conferences.
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Blood Pressure, Antihypertensive Use, and Late-Life Alzheimer and Non-Alzheimer Dementia Risk: An Individual Participant Data Meta-Analysis.

Neurology

September 2024

From the Faculty of Medicine and Health (M.J.L., D.M.L., B.C.P.L., J.D.C., P.S.S.), and Centre for Healthy Brain Aging (CHeBA) (M.J.L., D.M.L., B.C.P.L., J.D.C., P.S.S.), Discipline of Psychiatry & Mental Health, School of Clinical Medicine, University of New South Wales, Sydney; School of Psychology and Public Health (B.C.P.L.), La Trobe University, Melbourne; The George Institute for Global Health (A.E.S., R.P.), Barangaroo; School of Biomedical Sciences (R.P.), University of New South Wales, Sydney, Australia; School of Public Health (R.P.), Imperial College London, United Kingdom; School of Population Health (A.E.S.), University of New South Wales, Sydney, Australia; Neuropsychiatric Epidemiology Unit (T.R.-S., J.N., I.S.), Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg; Aging Research Center (T.R.-S.), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University; Region Västra Götaland (J.N., I.S.), Sahlgrenska University Hospital, Psychiatry, Cognition and Old Age Psychiatry Clinic, Gothenburg, Sweden; Section Genomics of Neurodegenerative Diseases and Aging (J.N.), Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; Institute of Social Medicine (S.G.R.-H., S.R., A.P.), Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Germany; School of Psychology (S.R.), Massey University, Albany Campus, Auckland, New Zealand; Global Brain Health Institute (GBHI) (S.R.), Trinity College Dublin, Ireland; Department of Medicine and Psychiatry (A.L., C.D.-l-C.), Universidad de Zaragoza; Instituto de Investigación Sanitaria Aragón (IIS Aragón) (A.L., C.D.-l-C., E.L.), Zaragoza; CIBERSAM (A.L., C.D.-l-C., E.L.), Madrid, Spain; Department of Preventive Medicine and Public Health (E.L.), Universidad de Zaragoza, Spain; Department of Neurology (R.B.L., M.J.K., C.A.D.), and Department of Epidemiology and Population Health (R.B.L., C.A.D.), Albert Einstein College of Medicine, Bronx, NY; Department of Neuropsychiatry (K.W.K., J.W.H.), Seoul National University Bundang Hospital, Seongnam; Department of Psychiatry (K.W.K., J.W.H.), Seoul National University College of Medicine; Department of Brain and Cognitive Sciences (K.W.K.), Seoul National University College of Natural Sciences; Workplace Mental Health Institute (D.J.O.), Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea; Golgi Cenci Foundation (E.R., A.D., M.R.), Abbiategrasso, Milan; Department of Brain and Behavioural Sciences (E.R.), University of Pavia, Italy; 1st Department of Neurology (N.S.), Aiginition Hospital, National and Kapodistrian University of Athens, Greece; Department of Neurology (N.S.), Columbia University, New York, NY; School of Health Sciences and Education (M.Y.), Department of Nutrition and Dietetics, Harokopio University; Department of Neurology (T.D.), University Hospital of Larissa; Faculty of Medicine (T.D.), School of Health Sciences, University of Thessaly, Larissa, Greece; Department of Psychiatry (H.C.H.), Indiana University School of Medicine; Indiana Alzheimer Disease Research Center (H.C.H., S.G.), Indiana Alzheimer Disease Research Center; Department of Biostatistics and Health Data Science (S.G.), Indiana University School of Medicine, Indianapolis; Institut for Neurosciences of Montpellier INM (I.C., K.R.), University Montpellier, INSERM; Institut du Cerveau Trocadéro (K.R.), Paris, France; School of Psychology (K.J.A.), and Ageing Futures Institute (K.J.A.), University of New South Wales; Neuroscience Research Australia (K.J.A.), Sydney; National Centre for Epidemiology and Population Health (N.C.), Australian National University, Canberra, Australia; Department of Geriatric Psychiatry (S.X., L.Y., W.L.), Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine; Alzheimer's Disease and Related Disorders Center (S.X., L.Y., W.L.), Shanghai Jiao Tong University, China; Inserm U1094 (M.G., P.-M.P., V.A.), IRD UMR270, Univ. Limoges, CHU Limoges, EpiMaCT-Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, France; Laboratory of Chronic and Neurological Diseases Epidemiology (LEMACEN) (M.G.), Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin; Department of Cardiology (V.A.), Dupuytren 2 University Hospital, Limoges, France; School of Medicine (M.N.H.), University of California, San Francisco; Robert N. Butler Columbia Aging Center (A.A.), Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Departamento de Psiquiatria (M.S.), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Brazil; and Neuropsychiatric Institute (P.S.S.), Prince of Wales Hospital, Sydney, Australia.

Article Synopsis
  • Previous studies suggest that using antihypertensive medication in older adults may lower the overall risk of dementia, but the effects on different types of dementia, particularly Alzheimer’s disease (AD), are still uncertain.
  • This research analyzed data from over 31,000 participants across multiple countries, focusing on how history of hypertension and blood pressure levels impact the risk of developing AD and non-AD types of dementia.
  • The findings indicated that untreated hypertension significantly increases the risk of developing AD and non-AD dementia compared to healthy individuals, while treated hypertension showed a similar risk for non-AD but not a significant difference between treated and untreated groups.
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