Iristectorin A Ameliorates Cisplatin-Induced Hepatorenal Injury in Mice Through Modulation of the Nrf2/HO-1 Signaling Pathway.

Cisplatin (CIS) is a chemotherapeutic agent frequently used in cancer treatment. However, depending on the dosage and duration of use, CIS can lead to hepatotoxicity and nephrotoxicity. Iristectorin A (IRIS), a natural flavonoid, has been found to exhibit antioxidant and protective effects.

Investigation of Damping Properties of Natural Fiber-Reinforced Composites at Various Impact Energy Levels.

Natural fiber-reinforced composites are composite materials composed of natural fibers, such as plant fibers and synthetic biopolymers. These environmentally friendly composites are biodegradable, renewable, cheap, lightweight, and low-density, attracting attention as eco-friendly alternatives to synthetic fiber-reinforced composites. In this study, natural fiber-reinforced polymer foam core layered composites were produced for the automotive industry.

Morphological Features of the Pecten Oculi in the Common Kestrel (Falco tinnunculus).

This study aimed to investigate the macroscopic, light microscopic (LM) and scanning electron microscopic (SEM) characteristics of the pecten oculi in common kestrels (Falco tinnunculus). A total of six eyeballs from three common kestrels were used as the study material. The examination revealed that the bulbus oculi was spherical in shape and its diameter exceeded the axial-global length.

Montelukast potentiates the relaxing effect of nifedipine in the porcine myometrium.

This study analysed the influence of montelukast (MON), a cysteinyl leukotriene receptor antagonist, and nifedipine, an L-type voltage-gated Ca2+ channel blocker, on the contractility of the porcine uterine smooth muscle. Myometrial strips were collected from the sexually immature (n=8), cyclic (12-14 days of the oestrous cycle; n=8) and pregnant (27-28 days of pregnancy; n=8) gilts and stimulated with a) MON or nifedipine at concentrations of 10-8-10-4 M and b) increasing concentrations of nifedipine after previous administration of MON at a concentration of 10-4 M. The changes in the tension, amplitude and frequency of contractions were determined with the Hugo Sachs Elektronik equipment for measuring isometric contractions.

Data Mining Implementations for Determining Root Causes and Precautions of Occupational Accidents in Underground Hard Coal Mining.

Background: Nowadays, as in every branch of industry, a large amount of data can be collected in mining, both in productivity and occupational safety. It is increasingly essential to transform this data into useful information for enterprises. Data mining is very useful in processing and extracting useful information from the processed data.

Multidimensional analysis of serving speed in volleyball players by position, sets, and league types: interactions and statistical differences.

Purpose: Our study explores the multifaceted factors influencing serve speed in volleyball, including player position, match progression, and league level, providing actionable insights for performance optimization and injury prevention strategies.

Methods: Using a cross-sectional approach, the study analyzes 15.347 serves from various leagues.

An insight into advanced glass systems for radiation shielding applications: A review on different modifiers and heavy metal oxides-based glasses.

Ionizing radiation from natural and many synthetic sources is a remarkable tool in many scientific, production, quality control, food preservation, medical, security, and other technological processes. The need to protect humans (public and personnel), gadgets, the environment, and animals from the harmful effects of radiation, while maintaining and expanding the scope of application has made radiation protection an important topic to discuss. Among the methods and materials available for radiation control, shielding and the use of glass shields are the most effective and attractive methods and materials, respectively.

ANN-based chaotic PRNG in the novel jerk chaotic system and its application for the image encryption via 2-D Hilbert curve.

In this paper, we introduce a category of Novel Jerk Chaotic (NJC) oscillators featuring symmetrical attractors. The proposed jerk chaotic system has three equilibrium points. We show that these equilibrium points are saddle-foci points and unstable.

The validity and reliability of the jump power app for measuring vertical jump actions in professional soccer players.

This research examines the reliability, validity, and usefulness of the Jump Power application by comparing it with the reliable and validated Optojump photoelectric cell system in measuring squat jump (SJ) and countermovement jump (CMJ) in professional athletes. Twenty-two soccer players volunteered to participate in the research. The participants were the players of the U21 team in the 1st League.

Locomotor performance parameters as predictors of high-performing male soccer teams. A multiple-season study on professional soccer.

This study aims to explore the interplay between locomotor demands and goal differentials to better understand their combined influence on overall success. Spanning three competitive seasons within the male Turkish Super League, this study analyzed all participating teams across 124 matches. Locomotor demands, including total distance (m) covered (TD), distances covered (m) at different speed thresholds (0.

Histopathological and radiological evaluation of the efficacy of hydroxyapatite-boric acid and hydroxyapatite-magnesium coated Kirschner wires on fracture healing in femoral diaphyseal fractures: an experimental study.

Background: Biomaterials used in fracture healing hold a significant place in orthopedics. This study aimed to develop biomaterials coated with hydroxyapatite (HA), boric acid (BA), and magnesium (Mg) and investigate their effects on fracture healing.

Methods: Sixty female Wistar Albino rats were included in the study.

Effect of Drilling Parameters and Tool Diameter on Delamination and Thrust Force in the Drilling of High-Performance Glass/Epoxy Composites for Aerospace Structures with a New Design Drill.

Real service requirements of the assembly performance and joining properties of design components are critical for composite usage in the aerospace industry. This experimental study offers a novel and comprehensive analysis of dry drilling optimization for glass-reinforced, high-performance epoxy matrix composites used in aerospace structures, focusing on thrust force and delamination. The study presents a first-time investigation into the combined effects of spindle speed (1000, 2250, 4000 and 5750 rpm), feed rate (0.

Protective Effects of Ascorbic Acid Against Cadmium-Induced Toxicity in the Placenta and Fetus of Rats.

This study aimed to determine the protective role of l-ascorbic acid in a pregnant rat model of cadmium-induced toxicity. Cadmium is a toxic heavy metal that can seriously harm placenta and fetus tissue in pregnant women. Forty-two healthy female Wistar albino rats (250-300 g weight and 14-16 weeks) were randomly distributed into six equal groups (n = 7): control, cadmium 1 mg (CD1), cadmium 5 mg (CD5), ascorbic acid (AA), CD1+AA, CD5+AA.

A new methacrylate-chitosan based blend and its ZnO containing nanocomposites: Investigation of thermal and biological properties.

Biobased materials are an important step towards a sustainable future. The need for these materials, which stand out in terms of their environmental and economic benefits, is increasing daily. This study includes the production of new bio based nanocomposites containing a blend of biopolymer chitosan (CS) and synthetic polymethacrylate derivative poly(2-oxo-2-(3,4,5-trifluoroanilino)ethyl-2-methylprop-2-enoate)(POTFAMA) and biosynthesized zinc oxide nanoparticles (ZnO NPs) by hydrothermal method.

Validity and reliability of velocity and power measures provided by the Vitruve linear position transducer.

This study aimed to determine the validity and between-day reliability of the mean velocity (MV), peak velocity (PV), mean power (MP), and peak power (PP) provided by the Vitruve linear position transducer at different submaximal loads in the free-weight and Smith machine back squat using GymAware as a reference point. Fourteen male sports science students (free-weight back squat one-repetition maximum [1RM]: 132.5 ± 28.

International medical students in Türkiye: a cross-sectional study on their reasons for choosing Türkiye and their demographic and socioeconomic characteristics.

The aim of this study is to investigate the reasons why international medical students choose Türkiye, which has one of the largest higher education capacities in Europe and is also among the top 10 most preferred countries in the world by international students, and their demographic and socioeconomic characteristics. The data of this cross-sectional study were collected through an online survey that included questions such as students' gender, age, ethnicity, monthly income, pre-school education, parental education level and professions, number of siblings, rural status of the region where they grew up, and reasons for choosing Türkiye. 482 students at various grade levels from 30 medical schools participated in the study.

Phytochemical composition, antimicrobial, antioxidant, and wound healing activities of .

The antioxidant, antimicrobial, anticarcinogenic, wound healing activities and phenolic substance profile of aqueous extracts prepared using branch, leaf, flower parts and above-ground parts of were determined in the study. The analyses indicate that the total phenolic substance contents and total antioxidant status are higher in the mix, flower, and leaf extracts. The extracts reduced cell viability in HGF cells more than in A549 cells.

Detection of body shape changes in obesity monitoring using image processing techniques.

Body measurements are primarily made with a tape measure. In measurements taken with a tape measure, the inability to take measurements from the same part of the body each time, incorrect positioning of the tape measure, the occurrence of incorrect measurements, and the need for a person to take the measurements are significant problems in the traditional measurement method. Due to the social distancing rule that must be followed during the Covid-19 pandemic, the close contact between the person to be measured and the person taking the measurement became the starting point of this study.

Intranasal Insulin Eases Autism in Rats via GDF-15 and Anti-Inflammatory Pathways.

In rat models, it is well-documented that chronic administration of propionic acid (PPA) leads to autism-like behaviors. Although the intranasal (IN) insulin approach is predominantly recognized for its effects on food restriction, it has also been shown to enhance cognitive memory by influencing various proteins, modulating anti-inflammatory pathways in the brain, and reducing signaling molecules such as interleukins. This study seeks to explore the potential therapeutic benefits of IN insulin in a rat model of autism induced by PPA.

Dissolution of EAF slag minerals in aqueous media: Effects of sonication on brownmillerite and gehlenite.

The accumulation of electric arc furnace slag (EAFS) in landfills has been causing severe environmental problems. This study examines the dissolution properties of EAFS minerals, including brownmillerite and gehlenite, essential for their possible use in resource recovery. An investigation was conducted to compare the effects of sonication and stirring on mineral dissolution while also assessing the usage of citrate as a complexing agent for gehlenite.