116 results match your criteria: "African Institute of Science and Technology[Affiliation]"

Background: Tuberculosis and diabetes mellitus are significant global public health challenges. In Sub-Saharan Africa, study findings regarding prevalence of diabetes mellitus amongst tuberculosis patients have been inconsistent and highly variable. Therefore, this systematic review and meta-analysis estimates the overall prevalence of diabetes mellitus among tuberculosis patients in Sub-Saharan Africa.

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Background: Hypertension is dramatically increasing in Africa with evidence of increased severity and resistance to treatment. Although angiotensin converting enzyme gene polymorphism is associated with higher prevalence of hypertension, the evidence is inconclusive on its influence on the emerging pattern in Africa. This meta-analysis is conducted to pool the available evidence to inform future research and interventions.

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coenurosis in Tanzania: a major and under-recognised livestock disease problem in pastoral communities.

Vet Rec

February 2019

Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

A neurological syndrome of small ruminants, known locally as '', has been reported among pastoralist livestock keepers in Tanzania. This study was carried out in four affected pastoral communities to determine the prevalence and associated risk factors, characterise the clinical signs and investigate the aetiology of the syndrome. Questionnaires were administered at all households (n=480) within four study villages.

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Multiple studies have investigated selection signatures in domestic cattle and other species. However, there is a dearth of information about the response to selection in genomes of highly admixed crossbred cattle in relation to production and adaptation to tropical environments. In this study, we evaluated 839 admixed crossbred cows sampled from two major dairy regions in Tanzania namely Rungwe and Lushoto districts, in order to understand their genetic architecture and detect genomic regions showing preferential selection.

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Background: Intimate Partner Violence (IPV) during pregnancy is a serious public health concern globally. Within Sub-Saharan Africa nearly 40% of women reported abuse by their intimate partners. In Ethiopia, study findings regarding prevalence and associated factors of IPV among pregnant women have been inconsistently reported and highly variable.

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Unfortunately, the original article was online published with error in the results section. The error is correction by this erratum.

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This project sought to investigate the domestic caprid rumen virome by developing a robust viral DNA isolation and enrichment protocol (utilizing membrane filtration, ultra-centrifugation, overnight PEG treatment and nuclease treatment) and using RSD-PCR and high throughput sequencing (HTS) techniques. 3.53% of the reads obtained were analogous to those of viruses denoting Siphoviridae, Myoviridae, Podoviridae, Mimiviridae, Microviridae, Poxviridae, Tectiviridae and Marseillevirus.

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Article Synopsis
  • Previous research suggests that patients of African ancestry may not respond as well to certain hypertension medications, leading to continued use of these without solid evidence in Ethiopia.
  • This study compared the effectiveness of three antihypertensive drugs (nifedipine, enalapril, and hydrochlorothiazide) on blood pressure reduction in Ethiopian patients from November 2016 to April 2017, using a randomized method.
  • Results showed that nifedipine significantly reduced systolic blood pressure more than the other drugs, but there was no significant difference in diastolic blood pressure effects among the groups.
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Increasing complexity in human-environment interactions at multiple watershed scales presents major challenges to sediment source apportionment data acquisition and analysis. Herein, we present a step-change in the application of Bayesian mixing models: Deconvolutional-MixSIAR (D-MIXSIAR) to underpin sustainable management of soil and sediment. This new mixing model approach allows users to directly account for the 'structural hierarchy' of a river basin in terms of sub-watershed distribution.

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Effects of NHF and distilled water on structure of pores in TiO nanotube arrays.

Sci Rep

August 2018

Department of Materials Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.

In this study, we report the influences of distilled water and ammonium fluoride (NHF) on morphology of pores in honeycomb-like titanium dioxide (TiO) nanotube arrays. We observed the structure and arrangement of pores in the TiO nanotube arrays based on scanning electron microscopy images and analyzed the spatial distribution of the pores using fast Fourier transform and Voronoi diagram. We studied the individual pore properties including pore diameter, wall thickness, and interpore distance and found that locally connected ordering defects decreased with increasing distilled water concentration.

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Background: Despite remarkable progress in the reduction of under-five mortality, childhood diarrhea is still the leading cause of mortality and morbidity in this highly susceptible and vulnerable population. In Ethiopia, study findings regarding prevalence and determinants of diarrhea amongst under-five children have been inconsistent. Therefore, this systematic review and meta-analysis estimates the pooled prevalence of diarrhea and its determinants among under-five children in Ethiopia.

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Seasonal variation of organic matter characteristics and fluoride concentration in the Maji ya Chai River (Tanzania): Impact on treatability by nanofiltration/reverse osmosis.

Sci Total Environ

October 2018

Membrane Technology Department, Institute of Functional Interfaces (IFG-MT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany; Water and Environmental Science and Engineering, Nelson Mandela African Institute of Science and Technology (NMAIST), Arusha, Tanzania. Electronic address:

The Maji ya Chai River in Northern Tanzania, a fluoride-rich tropical area, shows a seasonal variation of natural organic matter (NOM) and fluoride concentration. Water samples collected monthly during one year from two locations of the River were characterized. High levels of precipitation in the rainy seasons increased the total organic carbon (TOC) concentration to as high as 36 mgC L and diluted the fluoride concentration from a dry season high of 24 mg L to <4 mg L.

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Background: The relationship between undernutrition and HIV is bidirectional, ultimately contributing to quality of life and survival of affected individuals. Ethiopia is a sub-Saharan nation influenced by both undernutrition and HIV. In Ethiopia, although individuals are often dually impacted, the effect of undernutrition on the survival of HIV positive children on anti-retroviral therapy (ART) has not been well investigated.

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Corn and rice husks, agro-wastes available in large quantities in Tanzania, were used to remove Pb from aqueous solution. Husks were used in raw form, pyrolyzed form, and chemically modified form. Material characterization was carried out using the BET method, FTIR spectroscopy, SEM, pH, and cation exchange capacity analysis.

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Renewable energy powered membrane technology: Impact of pH and ionic strength on fluoride and natural organic matter removal.

Sci Total Environ

April 2018

Membrane Technology Department, Institute of Functional Interfaces (IFG), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany; Department of Water and Environmental Engineering, Nelson Mandela African Institute of Science and Technology, Arusha, Tanzania. Electronic address:

Real water pH and ionic strength vary greatly, which influences the performance of membrane processes such as nanofiltration (NF) and reverse osmosis (RO). Systematic variation of pH (3-12) and ionic strength (2-10g/L as total dissolved solids (TDS)) was undertaken with a real Tanzanian water to investigate how water quality affects retention mechanisms of fluoride (F) and natural organic matter (NOM). An autonomous solar powered NF/RO system driven by a solar array simulator was supplied with constant power from a generator.

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Fatty Acid Composition of Dried Fruits of Sclerocarya birrea, Diospyros blancoi and Landolphia kirkii.

Int J Environ Res Public Health

November 2017

Nanotechnology and Water Sustainability, College of Science Engineering and Technology, University of South Africa, Johannesburg 1710, South Africa.

Wild fruits are commonly consumed in the rural communities of South Africa. The information on their nutritionally important fatty acids is, however, limited. Three wild fruit species, , and from Limpopo Province were selected for evaluation of fatty acid content.

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Exploring the Role of IL-32 in HIV-Related Kaposi Sarcoma.

Am J Pathol

January 2018

Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands; Radboud Center of Infectious Diseases, Radboud University Medical Centre, Nijmegen, the Netherlands.

The intracellular proinflammatory mediator IL-32 is associated with tumor progression; however, the mechanisms remain unknown. We studied IL-32 mRNA expression as well as expression of other proinflammatory cytokines and mediators, including IL-1α, IL-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α, the proangiogenic and antiapoptotic enzyme cyclooxygenase-2, the IL-8 receptor C-X-C chemokine receptor (CXCR) 1, and the intracellular kinase focal adhesion kinase-1. The interaction of IL-32 expression with expression of IL-6, TNF-α, IL-8, and cyclooxygenase-2 was also investigated.

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Background: Although there are established drugs for treatment of cardiovascular diseases, due to adverse effects these drugs may not be clinically applicable to all patients. Recent trends have seen the emergence of drugs which act on funny current channels to induce selective heart rate reduction. Ivabradine is one such drug developed for coronary artery disease and heart failure.

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In this study, we investigated the deposition kinetics of polyvinylidene fluoride copolymerized with trifluoroethylene (P(VDF-TrFE)) particles on stainless steel substrates during the electrophoretic deposition (EPD) process. The effect of applied voltage and deposition time on the structure and ferroelectric property of the P(VDF-TrFE) films was studied in detail. A method of repeated EPD and heat treatment above melting point were employed to fabricate crack-free P(VDF-TrFE) thick films.

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In order to improve the conservation and sustainable utilization of the African catfish Clarias gariepinus of the Yala Swamp in Kenya, genetic diversity and population structure of Lakes Kanyaboli and Namboyo populations of the species were studied using DNA sequences of the mitochondrial D-loop control region. Genetic diversity inferred as haplotype and nucleotide diversities and number of singletons and shared haplotypes was higher in the Lake Kanyaboli population (LKG) than the Lake Namboyo population (LNG) of C. gariepinus.

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Seasonal variation of organic matter concentration and characteristics in the Maji ya Chai River (Tanzania): Impact on treatability by ultrafiltration.

Water Res

September 2016

Nelson Mandela African Institute of Science and Technology, Department of Water and Environmental Science and Engineering, P.O. Box 447, Arusha, Tanzania(1); Karlsruhe Institute of Technology, Institute of Functional Interfaces (IFG), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany. Electronic address:

Many waters in Tanzania exhibit high concentrations of organic matter and dissolved contaminants such as fluoride. Due to bacteria and virus removal, ultrafiltration (UF) is an attractive option for drinking water treatment, and when coupled with adsorbents, may compete with other established processes like nanofiltration (NF) for lower contaminant concentrations. The results presented here examine the characteristics and treatability of tropical natural organic matter (NOM) by UF as a function of seasonal variation.

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Article Synopsis
  • The giraffe's tall stature and unique cardiovascular adaptations are not fully understood, but studying its closest relative, the okapi, helps identify genetic differences.
  • Scientists sequenced the genomes of both animals and found specific genes (like those in the HOX, NOTCH, and FGF pathways) that likely contribute to the giraffe's distinct features.
  • Additionally, notable evolutionary changes were found in DNA repair and centrosome functions, highlighting how giraffes have adapted to their unique diets and tall structure.
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Peste des petits ruminants (PPR) is a highly infectious disease of sheep and goats that is caused by PPR virus, a member of the genus Morbillivirus that includes the viruses that cause rinderpest (RP) in cattle. RP was the first animal disease to be globally eradicated in 2011 and is only the second disease, after smallpox, to have ever been eradicated. PPR is one of the principal constraints to small ruminant production in Africa, Asia, and the Middle East.

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