4 results match your criteria: "Affliated Hospital of Zunyi Medical College[Affiliation]"
Effects of continuous infusion of etomidate at various dose rates on adrenal function in dogs.
BMC Anesthesiol
January 2016
Department of Anesthesiology, Affliated Hospital of Zunyi Medical College, No. 149 Dalian Road, Zunyi, Guizhou Province, 563003, China.
Background: Etomidate is a commonly used sedative in intravenous anesthesia. The aim of this study was to compare the effects of various etomidate doses administered by continuous infusion on adrenal function in dogs under general anesthesia.
Methods: Thirty-six healthy adult male dogs were randomly divided into six groups.
Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage.
Clin Exp Immunol
February 2014
Department of Cerebrovascular, the First Affliated Hospital of Zunyi Medical College, Zunyi, Guizhou, China.
Intracerebral haemorrhage (ICH) is a subtype of stroke that associated with neurological dysfunction and inflammation, which may be ameliorated by a neuroprotective strategy targeting the complement cascade. The protective effect of C5a-receptor antagonist (PMX53) solely and in combination with thrombin antagonist (argatroban) was investigated in the ICH mouse model, respectively. Adult male C57BL/6J wild-type (WT) mice and C3(-/-) mice were randomized to receive PMX53/argatroban 1, 3 and 5 days after ICH.
View Article and Find Full Text PDF[Studies on expression, purification, crystal growth and optimization of putative transcription factor LytR from Streptococcus pneumoniae].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
August 2013
Department of Medicine Laboratory, Affliated Hospital of Zunyi Medical College, Zunyi 563003, China.
The aim of the present study was to obtain the crystal of transcription factor LytR of streptococcus pneumoniae for X-ray crystal structure and function analysis. The LytR gene of D39 strains from Streptococcus pneumoniae (S. pn) was cloned into the prokaryotic expression vector pET32a(+), then overexpression was obtained in the E.
View Article and Find Full Text PDFExpression of metallothionein and Nrf2 pathway genes in lung cancer and cancer-surrounding tissues.
World J Surg Oncol
August 2013
Affliated Hospital of Zunyi Medical College, Department of Thoracic and Cardiovascular Surgery, Zunyi, Guizhou 563003, China.
Background: Nuclear factor (erythroid-derived 2)-like (Nrf)2 and metallothionein have been implicated in carcinogenesis. This study investigated the expression of Nrf2 and of Nrf2-targeted genes (NQO1 and GCLC) and the genes for the metallothionein (MT) isoforms (MT-1A and MT-2A) in human lung cancer and cancer-surrounding tissues.
Methods: Surgically removed lung cancer samples (n = 80) and cancer-surrounding tissues (n = 38) were collected from Zunyi Medical College Hospital, China.