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Advances in research on cell models for skeletal muscle atrophy.
Biomed Pharmacother
November 2023
Orthopaedic Center, Affliated Hospital of Guangdong Medical University, South Renmin Road 57, Xiashan District, Zhanjiang 524000, Guangdong, China. Electronic address:
Article Synopsis
- Skeletal muscle is the largest organ in the body and is vital for movement while also regulating protein synthesis and degradation.
- Muscle atrophy, a condition marked by reduced muscle mass and fiber size, can result from disrupted protein synthesis and various physiological factors, but the mechanisms behind it are not completely understood.
- The review focuses on different methods to create skeletal muscle cell models for studying muscle atrophy, analyzing techniques like hormone influences, inflammation, and genetic engineering to better understand the condition and its treatments.