2 results match your criteria: "Affiliated with the Southern Medical University[Affiliation]"
is positively correlated with in infection and a biomarker for mucosal injury.
iScience
July 2024
School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China.
Our study previously showed the involvement of Notch1 in Th1 differentiation in -infected patients. However, the role of Notch1 in Th17 or Treg differentiation during infection and the potential diagnostic value of its associated genes remain unclear. Here, we found that was positively correlated with Th17-related genes ( = 0.
View Article and Find Full Text PDFThe potential value of Notch1 and DLL1 in the diagnosis and prognosis of patients with active TB.
Front Immunol
April 2023
Xinhui District People's Hospital, Affiliated with the Southern Medical University, Jiangmen, China.
Objectives: The Notch signaling pathway has been implicated in the pathogenesis of active tuberculosis (TB), and Th1-type cell-mediated immunity is essential for effective control of mycobacterial infection. However, it remains unclear whether Notch signaling molecules (Notch1, DLL1, and Hes1) and Th1-type factors (T-bet and IFN-γ) can serve as biomarkers for tracking the progression of active TB at different stages along with peripheral blood white blood cell (WBC) parameters.
Methods: A total of 60 participants were enrolled in the study, including 37 confirmed TB patients (mild (n=17), moderate/severe (n=20)) and 23 healthy controls.