Correlation of Anthropometric Measurements with Insulin Resistance Assessed by HOMA-IR in Obese Normotensive Individuals: A Cross-Sectional Study in South India.

Background: The study aims to evaluate insulin resistance in obese individuals with normotensive diabetes using Homeostasis Model Assessment and correlate it with anthropometric measurements, highlighting the link between poor lifestyles and metabolic syndrome.

Methods: The research assessed the anthropometric, lipid, fasting blood glucose, hemoglobin A1C, serum insulin, and lipidosis profiles of 100 people using both traditional procedures and the Homeostatic model assessment (HOMA)-IR.

Results: A study of 100 participants, including 43 males and 57 females, found a significant waist-hip ratio (HOMA-IR >2.

Role of Genetic Mutations in Periodontitis Patients with Cardiovascular Diseases and Allied Ailments: A Systematic Review and Meta-analysis.

Background: Periodontal disease, a chronic inflammatory condition, has been increasingly associated with systemic health issues, particularly cardiovascular diseases. This systematic review and meta-analysis explores the role of genetic mutations in periodontitis patients with cardiovascular diseases and allied ailments.

Methodology: Conducted a comprehensive search across databases including PubMed, EMBASE, and Cochrane Library to identify relevant studies on the association between genetic mutations, periodontal disease severity, and cardiovascular outcomes.

Vascular Inflammatory Genes as Predictors of Preeclampsia: A Systematic Review.

Background: Preeclampsia, a condition causing new-onset hypertension and proteinuria after 20 weeks of gestation, is a significant cause of maternal and fetal morbidity and mortality. The pathogenesis of preeclampsia is complex, involving an interplay of vascular inflammation and angiogenic imbalance. This systematic review and meta-analysis aims to elucidate the role of key vascular inflammatory candidate genes-VEGF, TNF-α, IL-10, and LPL-in the onset of preeclampsia.

A Comparative Study of Euthyroid and Primary Hypothyroid Patients in End Stage Renal Disease (ESRD) Undergoing Maintenance Hemodialysis (MHD) in a Tertiary Care Hospital in Salem, Tamil Nadu.

Background And Aim: Hypothyroidism significantly alters renal function. Still, there are few scientific studies on thyroid disorders and how it influences renal function. Recent research suggested hypothyroidism may lower the glomerular filtration rate.

A Comparative Analysis of Diagnostic Accuracy: Vibration Perception Threshold vs. Diabetic Neuropathy Examination for Diabetic Neuropathy.

Background: Diabetes mellitus has emerged as a global health crisis, with its prevalence escalating dramatically. Diabetic peripheral neuropathy (DPN) stands out as one of the most frequent complications, leading to significant morbidity, including foot ulcers and amputations, if not identified and managed promptly. Effective screening methods are essential for early detection, which can significantly improve patient outcomes and reduce the risk of severe complications.

Association of Serum Albumin and C-Reactive Protein with Outcomes in ESRD Patients Undergoing Hemodialysis at a Tertiary Care Center in Salem, Tamil Nadu.

Background: Chronic kidney disease (CKD) is a chronic condition characterized by irreversible renal dysfunction, leading to excretory and metabolic failure. Patients with end-stage renal disease (ESRD) often have elevated CRP and reduced albumin levels, causing inflammation. This study compares serum CRP, albumin, urea, creatinine, eGFR, blood pressure, and weight in patients on MHD with ESRD.