Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model.

Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility, biodegradability, and non-toxicity. When combined with polyvinyl alcohol (PVA), the resulting hydrogels exhibit superior mechanical strength, elasticity, and swelling capacity, making them highly suitable for a range of applications, including wound healing, tissue engineering, and controlled drug delivery. In this study, we synthesized and characterized a novel PVA/gelatin/chitosan (PVA/G/C) hydrogel composite using a series of analytical techniques such as Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray analysis (EDAX).

Comprehensive study of Biginelli's compounds show antibacterial activity against Vibrio parahaemolyticus of two strains: In vitro and computational approaches.

This study addresses the critical challenges faced by global aquatic industries such as overfishing, habitat destruction, pollution, climate change, and unsustainable aquaculture practices. It focuses on developing effective solutions by synthesizing potent inhibitors against Vibrio parahaemolyticus of two strains namely: MTCC-451 (A) and Vp-S14 (B). Biginelli's compounds (B1-4) were identified as promising inhibitors with confirmed antibacterial activity through in silico and in vitro studies.

Sustained release of nano-encapsulated glimepiride drug with chitosan nanoparticles: A novel approach to control type 2 diabetes in streptozotocin-induced Wistar albino rats.

The objective of the present study was to encapsulate the effective antidiabetic glimepiride (GLM) drug with biodegradable chitosan nanoparticles (CS NPs) in order to reduce the risk of side effects, regulate and improve alternatives to therapy for people with type 2 Diabetes mellitus. The characterizations of the encapsulated EGLM-CS NPs were published in a previous paper. In continuation of the past study, here we report the in vitro and in vivo activities of EGLM-CS NPs in streptozotocin-induced diabetes Wistar albino rats orally treated for 28 days.

Novel adaptive control approach to fractal fractional order deforestation model and its impact on soil erosion.

Deforestation exerts profound ramifications on soil quality and biodiversity, thereby exerting substantial economic repercussions. The depletion of organic matter and structural integrity of soil following tree removal for agricultural purposes underscores the severity of this issue. In elucidating the soil pollution stemming from deforestation, this research employs a sophisticated five-compartment SDIFR model integrating fractal dimension and fractional order dynamics.

Alginate/CuO-gCN composite: a novel, reusable, non-toxic photocatalyst for methylene blue degradation.

Increasing industrial contamination necessitates development of sustainable water treatment solutions. Photocatalysis is a green technology utilizing light-activated materials (photocatalysts), which can degrade pollutants into harmless by-products. It is an emergent need to develop a photocatalyst that presents a significant advancement for sustainable water treatment and non-toxic to the environment.

Time-Dependent Hydrothermal Synthesis of LaO NPs for Effective Catalytic Activity of Ionic Dye.

Lanthanum oxide was successfully synthesized by hydrothermal method by varying the reaction time such as 6, 12, and 24 h. In XRD, study confirms the presence of a hexagonal structure, and the phase remains the same at different times; the main goal is to assess the average crystallite size of prepared LaO nanoparticles, which was found in the range of 6 to 8 nm. An interesting observation from the XRD data was the apparent increase in crystalline nature as the synthesis time was extended.

Fabrication of one-dimensional Zn-doped BiS nanorods for photodiode applications.

In this research, the impact of the different zinc (Zn) concentrations on the physical and optoelectronic properties of BiS nanorods as self-powered and photodiode applications was investigated. The performance of P-N junction photodiodes has been for decades since they are crucial in energy applications. The structure, degree of crystallinity, and shape of Zn-doped BiS nanorods of various doping percentages formed onto the indium tin oxide (ITO) substrates by the dip coating technique are investigated using X-ray powder diffraction (XRD) and SEM.

Synthesis, characterization and photocatalytic activity of alginate based hybrid material for efficient degradation of organic pollutants under UV light and sunlight irradiation.

This study reports the development of alginate based hybrid material (Alg/CuO-gC₃N₄) with copper oxide (CuO) and graphitic carbon nitride (gC₃N₄). The Alg/CuO-gC₃N₄ hydrogel bead was prepared by two step process is as follows: formation of CuO-gC₃N₄ by co-precipitation method and incorporation of CuO-gC₃N₄ in the calcium alginate (Alg) by ionotropic gelation method. The structural and morphological features of the Alg/CuO-gC₃N₄ was characterized using different techniques namely Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Thermogravimetric analysis (TGA), UV Diffuse Reflectance spectroscopy (UV-DRS) and Scanning electron microscopy (SEM).

Sustainable heavy metal (Cr(VI) ion) remediation: Ternary blend approach with chitosan, carboxymethyl cellulose, and bioactive glass.

Heavy metal pollution poses a significant environmental challenge to worldwide, especially in developing countries. This study focuses on eliminating the heavy metal chromium (VI) ion from wastewater, employing an eco-friendly and economical ternary blend composed of Chitosan (CS), Carboxymethyl cellulose (CMC), and bioactive glass (BAG). The innovative bioactive glass is crafted from biosilica extracted from biowaste of cow dung ash, calcium oxide from eggshell ash, and phosphorus pentoxide.

Bio fabricated palladium nano particles using phytochemicals from aqueous cranberry fruit extract for anti-bacterial, cytotoxic activities and photocatalytic degradation of anionic dyes.

The low cost and ecological compatibility of green technology makes it superior to chemical approaches in the generation of metal nanoparticles. The current study shows the use of cranberry fruit extract in the environmentally friendly green production of palladium nanoparticles. It is well known that the fruit extract from cranberries has a rich phytochemical composition that makes it a useful bio reducing agent for the formation of PdNPs.

Application of Novel Gill Cell Line from Lates calcarifer for Recognizing Metals Using Probes.

Lates calcarifer (Bloch) is a potential candidate fish species for culture in marine and brackishwater. A continuous gill cell line was derived from L. calcarifer by the explant culture method and has been passaged for 132 times, in Leibovitz's L-15 medium containing 10% fetal bovine serum (FBS) at 28 °C.

Development and characterization of brain cell line from Trachinotus blochii and its application in virological and gene expression studies.

A permanent cell line, SPB (Snubnose pompano brain) was established from Trachinotus blochii by the explant culture method. It has been sub-cultured more than 75 passages and showed optimal growth at 28°C using L-15 medium supplemented with 15% to 20% FBS. The SPB cells were cryopreserved at different passage levels for various applications.

Nickel-doped vanadium pentoxide (Ni@VO) nanocomposite induces apoptosis targeting PI3K/AKT/mTOR signaling pathway in skin cancer: An in vitro and in vivo study.

In the present study, the vanadium pentoxide (VO) nickel-doped vanadium pentoxide (Ni@VO) was prepared and determined for in vitro anticancer activity. The structural characterization of the prepared VO and Ni@VO was determined using diverse morphological and spectroscopic analyses. The DRS-UV analysis displayed the absorbance at 215 nm for VO and 331 nm for Ni@VO as the primary validation of the synthesis of VO and Ni@VO.

Biomedical and ecosafety assessment of marine fish collagen capped silver nanoparticles.

In the rapidly evolving landscape of silver nanoparticles (Ag NPs) synthesis, the focus has predominantly been on plant-derived sources, leaving the realm of biological or animal origins relatively uncharted. Breaking new ground, our study introduces a pioneering approach: the creation of Ag NPs using marine fish collagen, termed ClAg NPs, and offers a comprehensive exploration of their diverse attributes. To begin, we meticulously characterized ClAg NPs, revealing their spherical morphology, strong crystalline structure, and average diameter of 5 to 100 nm.

Ni/Co/Carbon nitride derived from ZIF-67 (MOF) nanocomposite: Enhanced light-driven photocatalytic degradation of methylparaben, mechanism & toxicity.

A nickel oxide/cobalt/carbon nitride (Ni/Co/CN) nanocomposite synthesized via co-precipitation was used for the degradation of methylparaben (MEP). Various analytical techniques were used to ascertain the structural, optical, and electrochemical characteristics of the synthesized nanocomposite. The unique nature of the compound without any free particles over the CN was established.

Biodegradation of naphthalene - Ecofriendly approach for soil pollution mitigation.

Naphthalene (NPT), a widely used household pest repellent and insecticide obtained from crude oil, serves as a toxic pollutant to non-target living matter. The stable and resistant nature of NPT makes it difficult to degrade through the physiochemical processes. The present study investigated the bacterial degradation of NPT isolated from crude oil-contaminated soil.

Cytotoxic, Antidiabetic, and Antioxidant Study of Biogenically Improvised and Chitosan-Assisted Zinc Oxide Nanoparticles.

In the present study, we have improvised a biogenic method to fabricate zinc oxide nanoparticles (ZnO NPs) using chitosan and an aqueous extract of the leaves of . Characterization of the fabricated products was carried out with the help of ultraviolet-visible, Fourier transform infrared, X-ray diffraction, field emission scanning electron microscopy, high-resolution transmission electron microscopy, selected area electron diffraction, and energy-dispersive X-ray analyses. The size of the improvised ZnO NP measured between 20 and 70 nm and had a spherical and hexagonal shape.

Radiological dose and associated risk due to Po in commercial inter-tidal bivalves of southwest (Arabian Sea) coast of India.

The activity concentration of Po was determined in edible tissues of commercial bivalves on the southwest coast of India. The Po activity ranged from 38.3 ± 6.

UPLC-ESI-Q-TOF-MS-based metabolomics analysis of sap and evaluation of osteogenic activity in mouse osteoblast cells.

Investigation of phytochemicals and bioactive molecules is tremendously vital for the applications of new plant resources in chemistry, food, and medicine. In this study, the chemical profiling of sap of Acer mono (SAM), a Korean syrup known for its anti-osteoporosis effect, was performed using UPLC-ESI-Q-TOF-MS analysis. A total of 23 compounds were identified based on the mass and fragmentation characteristics and most of the compounds have significant biomedical applications.

Multifunctional organic and inorganic hybrid bionanocomposite of chitosan/poly(vinyl alcohol)/nanobioactive glass/nanocellulose for bone tissue engineering.

The present study explored a novel organic-inorganic hybrid CPBNC bionanocomposite by developing chitosan (C)-poly(vinyl alcohol) (P)/nanobioactive glass (B)-nanocellulose (NC) with the addition of 1%, 2% and 3 wt% of nanocellulose as template material for bone tissue application. Nanobioactive glass of size 6-10 nm and nanocellulose of size 6-7 nm was confirmed by TEM analysis. X-ray diffraction and Fourier transform infrared spectroscopy indicated strong electrostatic interactions between the functional groups present in the CPBNC bionanocomposite.

The role of C-terminal helix in the conformational transition of an arginine binding protein.

The arginine binding protein (TmArgBP) is a periplasmic binding protein that has a short helix at the C-terminal end (CTH), which is swapped between the two chains. We apply a coarse-grained structure-based model (SBM) and all-atom MD simulation on this protein to understand the mechanism and the role of CTH in the conformational transition. When the results of SBM simulations of TmArgBP in the presence and absence of CTH are compared, we find that CTH is strategically located at the back of the binding pocket restraining the open-state conformation thereby disengaging access to the closed-state.

Evaluation of the radiological dose due to Po in commercial clupeid fish collected in the near-shore environment of the high background natural radiation area (HBNRA) on the southwest coast of India.

In this study, we quantified the tissue concentration of Po in a variety of commercial sardine fish species of the family Clupeidae from an area of high background natural radiation area on the southwest coast of India. The smooth belly sardine Amblygaster leiogaster had the lowest Po concentration in its muscle (45.6 ± 7.

Toxicological assessment of functional polymer with single-walled carbon nanotubes in zebrafish embryos and its gill cell line.

Carbon nanotubes (CNTs) have been widely used in developing polymer hybrid coatings for anticorrosive application. In the present study, poly [(3,5-dimethyl-lH-pyrazole-1-yl) methyl methacrylate-co-glycidyl methacrylate] (PyM) was prepared by solution polymerization. Single-wall carbon nanotubes (SWCNT) were incorporated in the PyM by solution blending technique at different proportions.