Staged surgery for tandem cervical and lumbar spinal stenosis: Which should be treated first?

Purpose: Tandem spinal stenosis (TSS) refers to lumbar and cervical spinal canal stenosis. Staged surgery is often chosen, but sometimes, mere decompression of one stenosis is adequate to relieve symptoms. Therefore, we intend to analyze whether starting with the cervical or the lumbar region is the most logical option.

Is Convex Derotation Equally Effective as Concave Derotation for Achieving Adequate Correction of Selective Lenke's Type- 1 Scoliosis?

Background: Correcting the scoliosis and stabilizing the spine in the corrected position is the basis of treatment for adolescent idiopathic scoliosis (AIS). Spinal instrumentation and derotation are the principle steps of surgery for any type of AIS. A perspicuous understanding needs to be attained regarding derotation maneuvers in practice; therefore, we intend to compare radiological outcomes following concave and convex rod derotation maneuvers to analyze their efficacy to correct selective Lenke's Type-1 scoliosis.

Expression of ameloblastin in the human tooth germ and ameloblastoma.

Objective: To analyse the immunohistochemical expression of ameloblastin in the bell stage of tooth germ and compare with ameloblastoma to determine the level of differentiation of tumour cells.

Study Design: This study included eleven human tooth germs with four in the early and seven in the late bell stage, and six selected archival tissue samples of ameloblastomas were studied using haematoxylin and eosin, Masson's trichrome and ameloblastin.

Results: All eleven tooth germs reacted positively to ameloblastin with a characteristic inverted and sequential pattern of expression in the acellular zone of the dental papilla and enamel organ.

Revalidating Pfirrmann's Magnetic Resonance Image-Based Grading of Lumbar Nerve Root Compromise by Calculating Reliability among Orthopaedic Residents.

Background: Intervertebral disc herniations lead to subsequent compromise of the nerve root. The root can either have a mere contact with the disc material or be pushed aside or compressed. This was earlier graded by Pfirrmann and colleagues.

The unresolved problem of beta-2 microglobulin amyloid deposits in the intervertebral discs of long-term dialysis patients.

Background: Dialysis-related destructive spondyloarthropathy caused by beta-2 microglobulin (β2M) amyloid deposits in intervertebral discs is a major burden for patients undergoing long-term dialysis. This study aimed to quantify the presence of β2M amyloid deposits in the intervertebral disc tissue of such patients and analyze whether there was a significant correlation between β2M accumulation and the duration of dialysis.

Methods: Two groups of patients who had undergone surgery for degenerative spinal pathologies were selected: the dialysis group (n = 29) with long-term dialysis and the control group (n = 10) with no renal impairment.

Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial.

Study Design: Prospective, randomized, double-blind clinical trial.

Objectives: To evaluate the efficacy of topical phenytoin solution in treating pressure ulcers among patients with spinal cord disorders and to evaluate the systemic absorption of topical phenytoin.

Setting: Physical Medicine and Rehabilitation Unit, Christian Medical College, Vellore, India.