1 results match your criteria: "Affiliated Zhangjiagang Hospital of Soochow University Suzhou 215600[Affiliation]"
Deubiquitinase PSMD7 regulates cell fate and is associated with disease progression in breast cancer.
Am J Transl Res
September 2020
Department of General Surgery, Affiliated Zhangjiagang Hospital of Soochow University Suzhou 215600, Jiangsu, China.
Article Synopsis
- Breast cancer is the most prevalent malignant tumor in women and the leading cause of cancer-related deaths.
- The study found that PSMD7, a protein linked to the proteasome, is significantly overexpressed in breast cancer tissues, correlating with factors like tumor subtype, size, and survival outcomes.
- Knockdown of PSMD7 led to cell cycle arrest and increased apoptosis, suggesting its potential as both a prognostic marker and a target for therapy in breast cancer.