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Impact of normocapnia vs. mild hypercapnia on prognosis after cardiac arrest: A systematic review and meta-analysis.

Am J Emerg Med

December 2024

Department of Emergency Intensive Care Unit, Yiling Hospital of Yichang, Affiliated Yiling Hospital of China Three Gorges University, Yichang 443002, Hubei Province, China. Electronic address:

Objective: To explore the impact of mild hypercapnia or normocapnia on the prognosis of patients after the return of spontaneous circulation (ROSC) following cardiac arrest (CA).

Methods: This systematic review and meta-analysis followed the guidelines in the PROSPERO report. Information was retrieved in PubMed, Cochrane Library, Embase, and Web of Science to collect all publications in English from January 1, 2000, to March 1, 2024, involving post-CA with mild hypercapnia.

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