2 results match your criteria: "Affiliated Tumor Hospital of Medical University[Affiliation]"

[Effect of pretreatment serum LDH and ALP levels on the prognosis of patients with nasopharyngeal carcinoma].

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

July 2017

Department of Head and Neck Surgery, Affiliated Tumor Hospital of Medical University, Nanning, 530021, China.

To investigate the effects of serum lactate dehydrogenase (LDH) and serum alkaline phosphatase (ALP) levels on the prognosis of patients with nasopharyngeal carcinoma (NPC) before treatment.Three hundred and thirty nine NPC cases, who were firstly treated in our hospital from April 2006 to October 2008, were enrolled in our study. Association of overall survival (OS) rate and disease-free survival (DFS) rate with clinical characteristics (age, gender, Tclassification, Nclassification, clinicalstage, radio therapy methods, radio therapy dose, the levels of pretreatment serum LDH) were evaluated using univariate and multivariate analysis methods.

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Objective: To study the changes of expression of Survivin mRNA, BCRP mRNA and HER-2 mRNA in breast cancer after TE regimen neoadjuvant chemotherapy, and to find biological markers to predict the efficiency of TE regimen neoadjuvant chemotherapy.

Methods: The gene expressions were detected by RT-PCR from 56 breast cancer patients before and after TE regimen neoadjuvant chemotherapy (docetaxel and epirubicin). The relationships between these gene expressions and chemotherapy responses were analyzed.

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