12 results match your criteria: "Affiliated Mental Health Center of Anhui Medical University[Affiliation]"

Metabolic and Endocrine Correlates of Subclinical Hypothyroidism in Young Adults With First-Episode and Drug-Naive Major Depressive Disorder.

J Acad Consult Liaison Psychiatry

November 2024

Affiliated Mental Health Center of Anhui Medical University, Hefei, China; Department of Psychiatry, Hefei Fourth People's Hospital, Hefei, China; Department of Psychiatry, Anhui Mental Health Center, Hefei, China. Electronic address:

Article Synopsis
  • Major depressive disorder (MDD) is frequently linked to subclinical hypothyroidism (SCH), but its characteristics in young, first-time, untreated patients are not well understood.
  • A study with 917 young Chinese individuals, aged 18-35, diagnosed with first-episode MDD was conducted, using various clinical assessments and biochemical tests to identify the prevalence and clinical correlates of SCH.
  • Results showed a 58% prevalence of SCH in this group, with significant predictors including higher depression severity, specific antibody levels, fasting blood glucose, and cholesterol levels, highlighting the importance of regular health monitoring to aid in early detection and treatment.
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Relationship between thyroid-stimulating hormone and blood lipids in patients with first-episode depression.

BMC Psychiatry

November 2024

Hefei Fourth People's Hospital; Anhui Mental Health Center, Affiliated Mental Health Center of Anhui Medical University, 316 Huangshan Road, Shushan District, Hefei, 230022, Anhui Province, China.

Background: Previous studies demonstrated thyroid stimulating hormone (TSH) plays an important role in regulating lipid metabolism, but the relationship between the two is controversial. Meanwhile, it has not been reported in a population with major depressive disorder (MDD).

Methods: We divided 1718 first-episode and drug naïve patients with MDD into a TSH abnormal group (TSH-AB) and a TSH normal group (TSH-NOR).

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Objective: The rate of drug craving not only in Pakistan is escalating rapidly, but also from a wide range of cultures and geographically have been impacted by the drug problem. Recently, drug cravings among young Pakistani school and college students have significantly increased, particularly illegal substances like hashish, heroin, and ecstasy.

Methods: We recruited 338 students and gathered demographic and drug-craving data through a survey.

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Exploring the impact of smartphone addiction on mental health among college students during the COVID-19 pandemic: The role of resilience and parental attachment.

J Affect Disord

December 2024

Affiliated Mental Health Center of Anhui Medical University, Hefei, China; Hefei Fourth People's Hospital, Hefei, China; Anhui Mental Health Center, Hefei, China. Electronic address:

Smartphone addiction is an increasingly severe issue in modern society, particularly impacting the mental health of college students during the COVID-19 pandemic. This study aims to explore the relationship between smartphone addiction and mental health issues among college students, and the mediating and moderating roles of psychological resilience and parental attachment. We employed a cross-sectional study design with 100,097 college Chinese students to examine the relationships between smartphone addiction, mental health (anxiety and depression), and the mediating role of psychological resilience.

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Neuroimaging markers of aberrant brain activity and treatment response in schizophrenia patients based on brain complexity.

Transl Psychiatry

September 2024

The Fourth People's Hospital of Chengdu, The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, PR China.

The complexity of brain activity reflects its ability to process information, adapt to environmental changes, and transition between states. However, it remains unclear how schizophrenia (SZ) affects brain activity complexity, particularly its dynamic changes. This study aimed to investigate the abnormal patterns of brain activity complexity in SZ, their relationship with cognitive deficits, and the impact of antipsychotic medication.

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Rationale: Several lines of evidence indicate that an insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme gene (ACE) gene may be involved in the pathogenesis of schizophrenia and cognitive impairment. However, the relationship between ACE I/D polymorphism and cognitive impairment in patients with schizophrenia remains unclear.

Objectives: The aim of this study was to examine whether ACE gene I/D polymorphism contributed to cognitive impairment in Chinese patients with schizophrenia, and whether the association between clinical symptoms and cognitive impairment depended on different ACE genotypes.

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