271 results match your criteria: "Affiliated Hospital of Yan'an University[Affiliation]"
Front Public Health
December 2024
Department of Radiation Oncology, The First Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Background: With the continuous progress and in-depth implementation of the reform of the medical and health care system, alongside the gradual enhancement of the standardized training framework for residents, such training has become a crucial avenue for cultivating high-level clinicians and improving medical quality. However, due to various constraints and limitations in their own capabilities, residents undergoing standardized training are often susceptible to job burnout during this process. Numerous factors contribute to job burnout, which is closely associated with depression and anxiety.
View Article and Find Full Text PDFJ Cancer
November 2024
Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an 716000, Shaanxi Province, China.
[This corrects the article DOI: 10.7150/jca.77905.
View Article and Find Full Text PDFFront Neurol
November 2024
Department of Neurology, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Introduction: The Oxidative Balance Score (OBS) represents an integrated measure of oxidative-reductive homeostasis. Despite the established role of oxidative stress in the development of post-stroke depression (PSD), the association between OBS and PSD in the general population remains unclear. This study aims to explore this relationship using data from the National Health and Nutrition Examination Survey (NHANES) spanning 2005-2018.
View Article and Find Full Text PDFZhonghua Gan Zang Bing Za Zhi
November 2024
Department of Infectious Diseases, Affiliated Hospital of Yan'an University, Key Laboratory of Yan'an, Yan'an716000, China.
To analyze the clinical characteristics of HBeAg-negative chronic hepatitis B virus (HBV) infection in indeterminate phase with a low viral load. One hundred and thirty-nine cases with persistent normal alanine aminotransferase (ALT) and HBeAg-negative chronic HBV infection with low viral load who visited the Department of Infectious Diseases of the Affiliated Hospital of Yan'an University from September 2013 to July 2021 were retrospectively collected. Patients were divided into low hepatitis B surface antigen (HBsAg) group (=59) and high HBsAg group (=80) according to the baseline hepatitis B surface antigen (HBsAg) level.
View Article and Find Full Text PDFJ Transl Med
November 2024
Department of Gastroenterology, The First Affiliated Hospital of Xi 'an Medical College, Xi 'an, China.
World J Gastroenterol
November 2024
Department of Infectious Diseases, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.
Background: The long-term stability of hepatitis B surface antigen (HBsAg) seroclearance following peginterferon alpha (peg-IFN-α)-based therapy has not been extensively studied, leaving the full potential and limitations of this strategy unclear.
Aim: To assess HBsAg recurrence after seroclearance achieved by peg-IFN-α regimens.
Methods: This prospective, multicenter, observational study was conducted from November 2015 to June 2021 at three Chinese hospitals: The Second Affiliated Hospital of Xi'an Jiaotong University, Ankang Central Hospital, and The Affiliated Hospital of Yan'an University.
Clin Nutr
December 2024
Department of Oncology, The Affiliated Hospital of Yan 'an University, 43 North Street, Baota District, Yan 'an City, Shaanxi Province, 716000, China. Electronic address:
Front Oncol
October 2024
Department of Radiation Oncology, The First Affiliated Hospital of Yan'an University, Yan'an, Shanxi, China.
Background: Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract worldwide. Both environmental and genetic factors contribute to the occurrence and development of GC. Surgery and chemotherapy are the main treatment modalities for gastric cancer; however, some patients show insensitivity to chemotherapeutic agents.
View Article and Find Full Text PDFZhongguo Gu Shang
October 2024
Department of Spine, Affiliated Hospital of Yan'an University, Yan'an 716000, Shaanxi, China.
Objective: To observe the safety and effectiveness of single dose intravenous infusion of tranexamic acid (TXA) in dual level posterior lumbar interbody fusion (PLIF), and to explore the changes and trends in perioperative white blood cell (WBC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP).
Methods: Between October 2020 and September 2022, 46 patients with lumbar degenerative disease were treated with dual level PLIF, including 18 males and 28 females, with an average age of (60.24±10.
Clin Nutr ESPEN
December 2024
Department of Oncology, The Affiliated Hospital of Yan 'an University, 43North Street, Baota District, Yan 'an City, Shaanxi Province, 716000, China. Electronic address:
Asian J Surg
September 2024
Department of Pathology, School of Medicine, Yan 'an University, 43 North Street, Baota District, Yan 'an, 716000, Shaanxi, China. Electronic address:
Medicine (Baltimore)
September 2024
Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Serum hemoglobin plays an important role in bone metabolism. However, the association between serum hemoglobin levels and bone mineral density (BMD) remains unclear. Therefore, this study aimed to explore the relationship between serum hemoglobin levels and lumbar spine BMD in adults.
View Article and Find Full Text PDFTransl Cancer Res
August 2024
Department of Gastrointestinal Colorectal and Anal Surgery, The China-Japan Union Hospital of Jilin University, Changchun, China.
Background: According to statistics, colon adenocarcinoma (COAD) ranks third in global incidence and second in mortality. The role of N6-methyladenosine (m6A) modification-dependent ferroptosis in tumor development and progression is gaining attention. Therefore, it is meaningful to explore the biological functions mediated by m6A ferroptosis related genes (m6A-Ferr-RGs) in the prognosis and treatment of COAD.
View Article and Find Full Text PDFSLAS Technol
October 2024
Department of Anesthesiology operation room, Cardio-Cerebrovascular Disease Hospital, Affiliated Hospital of Yan' an University, Yan' an City, Shaanxi Province 716000, China. Electronic address:
Background: Cerebral small vessel disease (CSVD) is a major cause of stroke, particularly in the elderly population, leading to significant morbidity and mortality. Accurate identification of high-risk patients and timing of stroke occurrence plays a crucial role in patient prevention and treatment. The study aimed to establish and validate a risk stratification model for stroke within three years in patients with CSVD using a combined MRI and machine learning algorithm approach.
View Article and Find Full Text PDFFront Microbiol
July 2024
Yan'an Key Laboratory of Microbial Drug Innovation and Transformation, School of Basic Medicine, Yan'an University, Yan'an, China.
Objective: To explore the effects of probiotic fermentation products of germinated grains on cognitive and sleep improvement in mice with sleep deprivation induced by chlorophenylalanine (PCPA), and to provide theoretical and experimental basis for the development of natural products to alleviate insomnia.
Methods: ELISA and high-performance liquid chromatography (HPLC) were used to determine the contents of γ-aminobutyric acid and L-theanine in fermentation products. Open Field Test was used to analyze the changes of emotional behavior between groups before and after intervention.
Int J Biol Sci
August 2024
Division of Cancer Biology, Laboratory Animal Center, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Leucine-rich repeat-containing 8A (LRRC8A) is a key component of the volume-regulated anion channel (VRAC) that influences essential homeostatic processes in various immune cells. These processes include the regulation of cell volume and membrane potential and the facilitation of the transport of organic agents used as anticancer drugs and immune-stimulating factors. Therefore, understanding the structure-function relationship of LRRC8A, exploring its physiological role in immunity, assessing its efficacy in treating diseases, and advancing the development of compounds that regulate its activity are important research frontiers.
View Article and Find Full Text PDFPLoS One
August 2024
Department of Neurology, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
BMC Pediatr
July 2024
Department of Pediatrics, the Affiliated Hospital of Yan'an University, Yan'an, 716000, China.
Background: Kawasaki disease (KD) is a pyretic ailment predominantly observed in children aged below 5 years. There is currently a dearth of precise markers for timely identification of incomplete Kawasaki disease (IKD). It is imperative to develop updated, comprehensive, and evidence-based guidelines to effectively direct clinical practice.
View Article and Find Full Text PDFBreast Cancer (Dove Med Press)
July 2024
Department of Medical College of Yan'an University, Yan 'an, People's Republic of China.
In recent years, more and more researches on cell death mode in breast cancer, including apoptosis, ferroptosis, etc. Ferroptosisis a regulated form of cell death characterized by iron-dependent accumulation of lipid peroxidation to lethal levels, and numerous studies have shown that ferroptosis is closely associated with tumor cells. Breast cancer is one of the malignant tumors with the highest incidence in women, and TNBC accounts for about 15-20% of all types of breast cancer.
View Article and Find Full Text PDFBMC Geriatr
July 2024
Department of Pulmonary and Critical Care Medicine of the Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Purpose: It is reported that insomnia and obstructive sleep apnea (OSA) increase the incidence of adverse cardiovascular events. The aim of this study was to analyze the risk of cardiovascular disease and mortality in elderly patients with comorbid insomnia and obstructive sleep apnea (COMISA).
Methods: We included 868 elderly patients with OSA who underwent sleep monitoring at a multicenter sleep room from January 2015 to October 2017.
J Magn Reson Imaging
July 2024
Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, The Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, Shaanxi, China.
Background: Turbo spin-echo (TSE) diffusion-weighted imaging (DWI) sequences may reduce susceptibility artifacts and image distortion in sellar region, allowing better visualization of small pituitary lesions, and may be used to assist in the diagnosis of pituitary microadenomas.
Purpose: To explore the application value of conventional MRI combined with DWI sequences in the diagnosis of microprolactinomas.
Study Type: Prospective.
Front Immunol
July 2024
Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Exosomes, as a class of small extracellular vesicles closely related to the biological behavior of various types of tumors, are currently attracting research attention in cancer diagnosis and treatment. Regarding cancer diagnosis, the stability of their membrane structure and their wide distribution in body fluids render exosomes promising biomarkers. It is expected that exosome-based liquid biopsy will become an important tool for tumor diagnosis in the future.
View Article and Find Full Text PDFCancer Biother Radiopharm
December 2024
School of Nursing and Health, Medical College of Yan 'an University, Yan 'an City, China.
Breast cancer is a leading cause of cancer-related deaths in women worldwide, posing a significant threat to female health. Therefore, it is crucial to search for new therapeutic targets and prognostic biomarkers for breast cancer patients. Bioinformatics analysis, quantitative real-time PCR (qRT-PCR), and fluorescence in situ hybridization (FISH) were employed to investigate the expression of hsa_circ_002144 in breast cancer.
View Article and Find Full Text PDFExp Neurol
September 2024
Center for Translational Medicine Research on Sensory-Motor Diseases, Yan'an University, Yan'an 716000, PR China; Key Laboratory of Yan'an Sports Rehabilitation Medicine, Yan'an 716000, PR China. Electronic address:
Pain in Parkinson's disease (PD) has been validated as one of the major non-motor dysfunctions affecting the quality of life and subsequent rehabilitation. In the present study, we investigated the role of the dopamine D3 receptor in the thalamic mediodorsal (MD) and ventromedial (VM) nuclei mediated descending control of nociception and intramuscular (i.m.
View Article and Find Full Text PDFPLoS One
June 2024
Department of Cardiology, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.