3 results match your criteria: "Affiliated Hospital of Shaoxing College of Arts and Sciences[Affiliation]"
Downregulation of lncRNA-PVT1 participates in the development of progressive chronic kidney disease among patients with congestive heart failure.
J Inflamm (Lond)
September 2021
Department of Nephrology, Affiliated Hospital of Shaoxing College of Arts and Sciences, No.999 South Central Road, Shaoxing, 312000, Zhejiang Province, PR China.
Background: Congestive heart failure (CHF) is a major cause of the development of progressive chronic kidney disease (CKD), while the mechanism is still unknown. LncRNA PVT1 contributes to kidney injury. This study aimed to explore the role of PVT1 in the development of CKD in CHF patients.
View Article and Find Full Text PDFLncRNA SNHG4 promotes osteosarcoma proliferation and migration by sponging miR-377-3p.
Mol Genet Genomic Med
August 2020
Department of Orthopaedics, Shaoxing Central Hospital, Shaoxing, Zhejiang, China.
Background: Long non-coding RNAs (lncRNAs) have been identified as crucial regulatory factors in the occurrence and progression of osteosarcoma.
Methods: Quantitative real-time polymerase chain reaction was used for detecting small nucleolar RNA host gene 4 (SNHG4) and miR-377-3p in osteosarcoma cells and tissues. Kaplan-Meier method was applied for evaluating the association between SNHG4 expression and the overall survival of osteosarcoma patients.
Stress-induced phosphoprotein 1 promotes pancreatic cancer progression through activation of the FAK/AKT/MMP signaling axis.
Pathol Res Pract
November 2019
Department of Radiology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, PR China. Electronic address:
Article Synopsis
- The stress-induced phosphoprotein 1 (STIP1) plays a significant role in promoting interactions between heat shock proteins Hsp70 and Hsp90, and its overexpression is linked to various human cancers, including pancreatic cancer (PANC), though its specific function in PANC is not well understood.
- Clinical studies reveal a strong correlation between high STIP1 expression and negative outcomes in PANC, such as lymph node involvement, metastasis, and overall patient prognosis, indicating that STIP1 may serve as an independent prognostic factor.
- Knockdown studies show that reducing STIP1 expression decreases the migratory and invasive capacities of pancreatic cancer cells while affecting the expression of key proteins involved in cancer progression, suggesting that STIP1