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Affiliated Hospital of Logistic Univers... Publications | LitMetric

20 results match your criteria: "Affiliated Hospital of Logistic University of Chinese People's Armed Police Force[Affiliation]"

Specific study about the inhibitory effect of costunolide (CN) and relevant mechanism is of great significance for the treatment of pulmonary fibrosis. Here, the pharmacological activity of costunolide on the treatment of pulmonary fibrosis was investigated in vivo and in vitro. The in vivo mice study, mice were received intratracheal injection of bleomycin (BLM, 5 mg/kg) on 0 day to obtain BLM-induced pulmonary fibrosis firstly.

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Traumatic brain injury (TBI) is the most common cause of death and permanent disability in people aged <45, and is associated with secondary brain injury and bleed progression, resulting in increased morbidity and mortality. TBI may also induce innate host defense responses characterized by activation of resident microglia and astrocytes, brain microvascular endothelial cells and peripheral blood monocytes. In the present study, 34 patients with moderate‑to‑severe traumatic brain injury were randomly divided into two groups, including a 7.

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Background: The present study was designed to explore the difference between two rat models of sepsis and to establish a more stable rat model.

Materials And Methods: Sprague-Dawley rats were randomly divided into three groups: sham operation group, simple cecal ligation and perforation group (SCLP), and cecal ligation perforation plus drainage group (CLP-DS). The general condition of the rats was observed, and the time of death and survival rate at 72 h were recorded.

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Objective: The objective of the study was to analyze the effect of environmental factors on the differential expression of microRNAs in the peripheral blood of migratory and local patients in northern People's Republic of China and on clinical symptoms of local patients in northern People's Republic of China with COPD.

Methods: A total of 118 patients in the northern region and 8 migratory patients were enrolled in this prospective study. We collected general information.

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Using a new plateau hyperbaric chamber to alleviate high altitude hypoxia: Rabbit and human studies.

Am J Emerg Med

October 2017

Medical College of Chinese PLA, Chinese PLA General Hospital, 28#, Fu-Xing Road, Haidian District, Beijing 100853, China; Department of Respiratory, General Hospital of Chinese People's Armed Police Force, China.

Article Synopsis
  • The study tested a new type of chamber that helps people breathe better when they're at high altitudes, like on Mount Kun Lun.
  • Researchers watched rabbits and adult volunteers at different heights to see how the chamber affected their breathing and heart rates.
  • Results showed that people and rabbits had better oxygen levels after using the chamber, but more testing is needed to see how well it works in real life.
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Pulmonary fibrosis, a progressive and lethal lung disease, is a major therapeutic challenge for which new therapeutic strategies are warranted. Schisandrin B (Sch B) and Glycyrrhizic acid (GA) are the principal active ingredients of Schisandra chinensis and Glycyrrhiza glabra respectively, which have been reported to protect against lung injures. The present study was aimed at exploring the combinatorial therapeutic effects on bleomycin-induced pulmonary fibrosis.

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Synthesis and immunogenicity of PG-tb1 monovalent glycoconjugate.

Eur J Med Chem

July 2017

CanSino Biologics Inc., Tianjin Enterprise Key Laboratory of Respiratory Bacterial Recombination and Conjugated Vaccine, Tianjin 300457, China. Electronic address:

A PG-tb1 hapten from the West Beijing strains of Mycobacterium tuberculosis cell wall has been efficiently synthesized and conjugated to CRM in a simple way as linker-equipped carbohydrate by applying squaric acid chemistry for an original neoglycoprotein, creating a potent T-dependent conjugate vaccine. The intermediate monoester can be easily purified and the degree of incorporation can be monitored by MALDI-TOF mass spectrometry. After administered systemically in mice without any adjuvant, the conjugate induced high antigen-specific IgG levels in serum.

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Challenges of Treating Adenovirus Infection: Application of a Deployable Rapid-Assembly Shelter Hospital.

Disaster Med Public Health Prep

February 2018

Institute of Disaster Medicine and Public Health, Affiliated Hospital of Logistic University of Chinese People's Armed Police Force (PAPF),and Key Laboratory of Emergency and Disaster Medicine in Chinese People's Liberation Army (PLA),Tianjin,China.

Article Synopsis
  • - The article discusses the formation of a rescue team and deployment of a field hospital to address an adenovirus outbreak, involving 59 members and various medical facilities tailored for emergency response.
  • - The field hospital included advanced equipment like CT and X-ray shelters, while the team consisted of medical professionals who effectively treated over 3,000 patients in 22 days without any fatalities.
  • - Emphasizing the need for rapid response in less-developed areas, the article highlights the importance of having a detailed action plan for managing infectious disease emergencies.
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Intratracheal Instillation of Perfluorohexane Modulates the Pulmonary Immune Microenvironment by Attenuating Early Inflammatory Factors in Patients With Smoke Inhalation Injury: A Randomized Controlled Clinical Trial.

J Burn Care Res

April 2018

From the *Institute of Disaster Medicine and Public Health, Affiliated Hospital of Logistic University of Chinese People's Armed Police Force (PAP), Tianjin, China; †Key laboratory of Emergency and Disaster Medicine in Chinese People's Liberation Army (PLA), Tianjin, China; and ‡Department of Medicine, Karolinska Institute, Stockholm, Sweden.

Smoke inhalation injury (SII) is associated with significant morbidity and mortality in burn patients, and effective treatments are lacking. Perfluorocarbons (PFCs) have a protective effect against acute lung injury. We aimed to assess the therapeutic effects of perfluorohexane on burn patients with SII.

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Quality of life in long-term oral cancer survivors: an 8-year prospective study in China.

Oral Surg Oral Med Oral Pathol Oral Radiol

January 2017

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, PR China. Electronic address:

Objectives: The purpose of the prospective study was to evaluate the long-term changes in quality of life (QOL) in patients with oral cancer and to examine the potential factors that predicted QOL at 8 years after treatment.

Study Design: Seventy-one patients were evaluated by the University of Washington quality of life scale. QOL in 30 long-term survivors was assessed at diagnosis and at the 3-month, 1-year, and 8-year follow-up.

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Objective: To retrospectively analyze the rescue and treatment of pediatric patients by the Chinese Red Cross medical team during the Nepal earthquake relief.

Methods: The medical team set up a field hospital; the pediatric clinic consisted of 1 pediatrician and several nurses. Children younger than 18 years old were placed in the pediatric clinic for injury examination and treatment.

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Multiple preclinical evidences have supported the potential value of mesenchymal stem cells (MSCs) for treatment of acute lung injury (ALI). However, few studies focus on the dynamic tropism of MSCs in animals with acute lung injury. In this study, we track systemically transplanted human bone marrow-derived mesenchymal stem cells (hBMSCs) in NOD/SCID mice with smoke inhalation injury (SII) through bioluminescence imaging (BLI).

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In Vivo Tracking of Systemically Administered Allogeneic Bone Marrow Mesenchymal Stem Cells in Normal Rats through Bioluminescence Imaging.

Stem Cells Int

September 2016

Institute of Disaster Medicine and Public Health, Affiliated Hospital of Logistic University of Chinese People's Armed Police Force, Tianjin, China; Key Laboratory of Emergency and Disaster Medicine in Chinese People's Liberation Army (PLA), Tianjin 300162, China.

Recently, mesenchymal stem cells (MSCs) are increasingly used as a panacea for multiple types of disease short of effective treatment. Dozens of clinical trials published demonstrated strikingly positive therapeutic effects of MSCs. However, as a specific agent, little research has focused on the dynamic distribution of MSCs after in vivo administration.

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The present study was aimed at exploring the protective effects of Salvianolic acid B (SalB) against paraquat (PQ)-induced lung injury in mice. Lung fibrotic injuries were induced in mice by a single intragastrical administration of 300mg/kg PQ, then the mice were administrated with 200mg/kg, 400mg/kg SalB, 100mg/kg vitamin C (Vit C) and dexamethasone (DXM) for 14days. PQ-triggered structure distortion, collagen overproduction, excessive inflammatory infiltration, pro-inflammatory cytokine release, and oxidative stress damages in lung tissues and mortality of mice were attenuated by SalB in a dose-dependent manner.

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Continuous plasma perfusion of dual cartridges in series: rationale and early clinical experience.

J Artif Organs

December 2016

Department of Respiratory and Critical Care Medicine of Ping Jing Hospital, Affiliated Hospital of Logistic University of Chinese People's Armed Police Force, 220#, Cheng-Lin Road, Tianjin, 300162, China.

To improve the efficiency of plasma perfusion on eliminating plasma paraquat (PQ), we designed continuous plasma perfusion of dual cartridges in series (CPPDCS) on Diapact Braun CRRT machine. The goals of this study were to evaluate the effective of CPPDCS on paraquat removal in patients with acute paraquat intoxication. Our results show that the PQ clearance rate of dual cartridges was significantly higher than that of single cartridge at 1st, 2nd, 3, and 4th plasma perfusion.

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Disaster can strike people in any community at any time anywhere in the world. Disasters occur with high frequency, take on multiple forms, and exert wide influence, typically causing property damage, injuries, and death. As the world's largest developing country, China incurs great costs when a disaster hits.

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On April 25, 2015, a massive 8.1-magnitude earthquake struck Nepal at 2:11 pm (Beijing time). The 68-member-strong China International Search & Rescue Team (CISAR) left for Nepal at 6 am, April 26, to help with relief work.

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Acute kidney injury (AKI) is a serious complication of sepsis. Zingerone, a phenolic alkanone isolated from ginger, has been reported to have anti-inflammatory effect. The aim of this study was to investigate the therapeutic effects of zingerone on lipopolysaccharide (LPS)-induced AKI in mice.

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Development and preliminary test of a new plateau hyperbaric chamber.

Am J Emerg Med

October 2015

Department of Respiratory, General Hospital of Chinese People's Armed Police Force, No. 69, Yong-ding Road, Haidian District, Beijing, 100039, China. Electronic address:

Objective: The objective of this study is to validate the performance, define its limits, and provide details on a new plateau hyperbaric chamber at 355-, 2880-, and 4532-m high altitude.

Methods: A new multiplace plateau hyperbaric chamber was designed to satisfy the needed of patients who have acute mountain sickness. Tests were conducted inside the chamber at 355-, 2880-, and 4532-m high altitude.

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Unlabelled: : An earthquake with a magnitude of 7.0 struck Lushan in Sichuan Province in China on April 20, 2013. Uniformed pediatricians visited the area where the epicenter was located to provide emergency relief care for children 10 days after the earthquake.

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