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Hepatitis B virus genetic mutations and evolution in liver diseases.
World J Gastroenterol
May 2014
Tao Shen, Xin-Min Yan, Institute of Basic and Clinical Medicine, Center of Clinical Molecular Biology, Provincial Key Laboratory for Birth Defects and Genetic Diseases, the First People's Hospital of Yunnan Province, Affiliated Hospital of Kumning Science and Technology University, Kunming 650032, Yunnan Province, China.
Hepatitis B virus (HBV) belongs to the genus Orthohepadnavirus of the Hepadnaviridae family and is approximately 3.2 kb in length. Owing to a lack of proofreading capacity during reverse transcription and a high replication rate, HBV exhibits as quasispecies.
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