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Tra2β protects against the degeneration of chondrocytes by inhibiting chondrocyte apoptosis via activating the PI3K/Akt signaling pathway.
Eur Rev Med Pharmacol Sci
September 2020
Department of Orthopaedics, Affiliated Hospital of Jiangnan University (Wuxi No. 3 People's Hospital), Wuxi, China.
Objective: Osteoarthritis (OA) is a common disease in the elderly and seriously affects the quality of life of patients. Tra2β is a protein that has been found to activate PI3K/Akt in recent years. The purpose of this study was to explore the protective effects of Tra2β on chondrocytes and its mechanisms.
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