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Article Synopsis
  • Oral squamous cell carcinoma (OSCC) is the most prevalent oral cancer, and researchers have linked microRNAs (miRNAs) to its detection and prognosis.
  • Recent advancements have led to the development of a biosensor that uses red-emitting upconversion nanoparticles (UCNPs) and an enzyme-free method to amplify signals, enhancing the detection of low-abundance miRNAs.
  • The new biosensor demonstrated high accuracy in measuring miRNA-222 in serum samples, showing results comparable to traditional PCR methods and suggesting its potential for analyzing various biological samples.
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