6 results match your criteria: "Affiliated Hospital of Guangdong Medical College Zhanjiang 524001[Affiliation]"
Efficacy of concurrent single-agent chemotherapy using radiotherapy in patients with cervical cancer: a meta-analysis.
Int J Clin Exp Med
August 2015
Department of Gastrointestinal Surgery, The Affiliated Hospital of Guangdong Medical College Zhanjiang 524001, Guangdong, China.
Concurrent chemoradiotherapy has proven to be more effective on patients with advanced cervical cancer than radiotherapy alone. Although cisplatin has been recommended to be the standard agent in chemotherapy, it has some limitations in clinical use because of its strong side effects. Moreover, the optimal chemotherapy regimen remains unclear.
View Article and Find Full Text PDFFBXO31 promotes cell proliferation, metastasis and invasion in lung cancer.
Am J Cancer Res
July 2015
Clinical Research Center, Guangdong Medical College Zhanjiang 524001, China ; Department of Respiratory Medicine, Affiliated hospital of Guangdong Medical College Zhanjiang 524001, China.
FBXO31 is a member of F-box family which is involved in diverse biological functions and development of disease. Recent reports in breast cancer, hepatocellular carcinoma and ovarian cancer demonstrated inhibitory effect of FBXO31 on proliferation and tumorigenesis. However, the function of FBXO31 is not analyzed in lung cancer so far.
View Article and Find Full Text PDFElevated HMGB1-related interleukin-6 is associated with dynamic responses of monocytes in patients with active pulmonary tuberculosis.
Int J Clin Exp Pathol
March 2016
Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics 1 Xincheng Road, Dongguan 523808, People's Republic of China ; Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College No. 1 Xincheng Road, Dongguan 523808, People's Republic of China.
Article Synopsis
- The study investigated the role of HMGB1 in patients with active pulmonary tuberculosis (APTB) by measuring its levels in plasma and sputum, along with various inflammatory cytokines and immune cells.
- Results showed that APTB patients had significantly higher levels of HMGB1 and cytokines (IL-6, IL-10, and TNF-α) compared to healthy volunteers, indicating an association with inflammation.
- The findings suggest that HMGB1 could serve as a potential biomarker for diagnosing and predicting the prognosis of APTB, reflecting the inflammatory state of monocytes in these patients.
Effects of α-enolase (ENO1) over-expression on malignant biological behaviors of AGS cells.
Int J Clin Exp Med
March 2015
Department of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang 524001, China.
Objective: To investigate the effects of α-Enolase (ENO1) over-expression on the proliferative and migratory abilities of AGS cells.
Methods: The target gene was cloned and mounted to the eukaryotic expression vector pcDNA3.1(+), then was transfected into gastric cancer cell lines AGS.
Clinicopathologic features of renal epithelioid angiomyolipoma: report of one case and review of literatures.
Int J Clin Exp Pathol
November 2015
Laboratory of Urologic Surgery, Affiliated Hospital of Guangdong Medical College Zhanjiang 524001, China.
Epithelioid angiomyolipoma (EAML) is a rare renal mesenchymal tumor with malignant potential and is frequently associated with tuberous sclerosis complex (TSC). As metastasis of the tumor cells occur early, EAML is considered a potentially malignant tumor type and intrigues further research on it. Under the microscope, we could find the tumor was composed of atypical polygonal cells sheet mixed with classic angiomyolipoma (AML) components such as blood vessels with notable thick vascular walls, smooth muscle-like cells and adipocytes.
View Article and Find Full Text PDFEffect of stable transfection with PHD3 on growth and proliferation of HepG2 cells in vitro and in vivo.
Int J Clin Exp Med
September 2014
Department of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang 524001, China.
Objective: To establish a human hepatoma HepG2 cell line with stable expression of Prolyl hydroxylase domain 3 (PHD3) gene and study its effect of growth and proliferation in nude mice xenograft tumor.
Methods: Eukaryotic expression vectors of pcDNA 3.1-PHD3 was constructed.