1 results match your criteria: "Affiliated Drum Tower Clinical Hospital of Nanjing University of Traditional Chinese Medicine[Affiliation]"
[Effects of zhengqing fengtongning tablet and methotrexate on the serum OPG/RANKL and IL-17 of collagen-induced arthritis rats].
Zhongguo Zhong Xi Yi Jie He Za Zhi
February 2013
Department of Rheumatology and Immunology, Affiliated Drum Tower Clinical Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing (210008), China.
Objective: To study the effects of Zhengqing Fengtongning Tablet (ZFT) and methotrexate (MTX) on the expression of osteoprotegerin (OPG), receptor activator of nuclear factor-kappaB ligand (RANKL), and interleukin 17 (IL-17) in collagen-induced arthritis (CIA) rats, thus addressing their bone protection.
Methods: The CIA rat model was established by intradermally injecting type II collagen emulsion from the rats' back and tail. Totally 28 successfully modeled rats [with the arthritis index (AI) more than 2] were randomly divided into the model group, the Chinese medicine (CM) treatment group, the MTX group, and the ZFT + MTX treatment group, 7 rats in each group.