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Article Synopsis
- A high-salt diet in mice leads to cognitive issues and reduced synaptic protein levels due to changes in gut microbiota and short-chain fatty acid production.
- Mice with gut microbiota from high-salt diet-fed mice show impaired memory and synapse function when placed on a regular diet.
- Treatment with butyrate, a short-chain fatty acid, helps improve memory impairments in mice that were on a high-salt diet, highlighting the gut microbiome's significant role in cognitive health.