Nursing countermeasures for VSD treatment of orthopedic trauma and infected wounds.

Objective: This study intended to investigate the effect of vacuum sealing drainage (VSD) in the treatment of orthopedic trauma and its role in the clinical care.

Methods: A total of 104 patients with orthopedic trauma infection admitted to our hospital from January 2019 to January 2020 were divided into control group (n=53, receiving VSD) and study group (n=51, receiving VSD and nursing interventions) by random number table. Surgical outcomes, satisfaction, size of trauma and visual analogue scoring scale (VAS) scores were compared between the two groups.

MAPK interacting serine/threonine kinase 1 (), one target gene of miR-223-3p, correlates with neutrophils in sepsis based on bioinformatic analysis.

Sepsis, resulting from a harmful or damaging response to infection, is a complex and severe disease that causes high mortality. Three independent expression profiles of miRNA - GSE94717, GSE149764, and GSE101639 - were collected and integrated to analyze miRNAs associated with sepsis. One miRNA, miR-223-3p, was detected significantly downregulated in patients with sepsis.

Aloperine protects human retinal pigment epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis through activation of Nrf2/HO-1 pathway.

Age-related macular degeneration (AMD) is a complex multifactorial disease associated with the dysfunction of retinal pigment epithelium (RPE). Aloperine is a quinolizidine alkaloid that has been proven to possess broad pharmacological activities. However, the effects of aloperine on AMD remain unclear.

Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients.

Background: Thyroid carcinoma (THCA) is one of the most common malignancies of the endocrine system, which is usually treated by surgery combined with iodine-131 (I) radiotherapy.

Aims: This study is aimed at exploring the potential targets of I radiotherapy in THCA.

Methods: The RNA-sequencing data of THCA in The Cancer Genome Atlas database (including 568 THCA samples) was downloaded.

Ultrasonic examination of differences in bone density of chronic obstructive pulmonary disease (COPD) rats constructed by different methods.

Background: Osteoporosis is one of the main complications of chronic obstructive pulmonary disease (COPD) patients. We investigated the bone density in rat model of COPD induced by different method.

Methods: We developed seven distinct groups to evaluate the differences in bone density.

A Allele of Rs5498 and Rs3181092 is Correlated with Increased Risk for Periodontal Disease.

Objective: Periodontal disease (PD) is viewed today as multifactorial problems initiated and sustained by bacteria but significantly modified by the body's response to bacterial plaque. Recent studies have suggested that gene polymorphisms could be involved in the pathophysiology of periodontitis. This study aimed to investigate a possible correlation of the polymorphisms of intercellular adhesion molecule-1 () and vascular cell adhesion molecule-1 () with PD.