10 results match your criteria: "Affiliated Cancer Hospital of Zheng Zhou University[Affiliation]"
Efficacy and safety of sovleplenib (HMPL-523) in adult patients with chronic primary immune thrombocytopenia in China (ESLIM-01): a randomised, double-blind, placebo-controlled, phase 3 study.
Lancet Haematol
August 2024
Thrombosis and Haemostasis Diagnosis Treatment Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China. Electronic address:
Article Synopsis
- Sovleplenib, a new SYK inhibitor, showed effective results and safety in treating patients with chronic primary immune thrombocytopenia in a phase 3 trial conducted in China.
- The trial involved 188 participants who were given either sovleplenib or a placebo, with results showing a significant durable response rate of 48% for sovleplenib compared to 0% for the placebo group.
- The study demonstrated a faster median time to response of 8 days for patients on sovleplenib versus 30 days for those receiving placebo, highlighting its potential efficacy in this condition.
Laparoscopic resection of low-position teratoma behind the rectum - a video vignette.
Colorectal Dis
October 2023
Department of General Surgery, Affiliated Cancer Hospital of Zheng Zhou University, Zhengzhou, China.
Surgical Efficacy and Prognosis of 54 Cases of Spinal Metastases from Breast Cancer.
World Neurosurg
September 2022
Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, University of Peking, Peking, China.
Objective: To analyze the efficacy and complications of spinal metastasis surgery for breast cancer; to understand the survival and the influencing factors; and to verify the predictive ability of the currently used spinal metastasis cancer survival prediction scoring system on 1 year postoperative survival.
Methods: A retrospective study was conducted of 54 patients with spinal metastases from breast cancer who underwent open surgery after multidisciplinary consultation in our hospital from January 2017 to October 2020. Patient demographic-related variables, breast cancer-related variables, spinal disorder-related variables, and treatment-related variables were collected.
Long-Term Efficacy and Safety of Anlotinib as a Monotherapy and Combined Therapy for Advanced Sarcoma.
Onco Targets Ther
June 2022
Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Peking University, Beijing, 100035, People's Republic of China.
Objective: To analyze the effectiveness of the long-term (> 12 months) administration of anlotinib as a monotherapy or combined therapy in patients with advanced sarcomas.
Methods: A retrospective analysis was conducted of patients with advanced sarcomas with measurable target lesions since 2018. Twenty-two of the patients had taken anlotinib regularly for > 12 months.
The Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) burden of care study: Analysis of local treatments for lung metastases and systemic chemotherapy in 220 patients in the PulMiCC cohort.
Colorectal Dis
November 2021
Sussex Health Outcomes Research and Education in Cancer (SHORE-C), University of Sussex, Falmer, UK.
Aim: The aim of this work was to examine the burden of further treatments in patients with colorectal cancer following a decision about lung metastasectomy.
Method: Five teams participating in the Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) study provided details on subsequent local treatments for lung metastases, including the use of chemotherapy. For patients in three groups (no metastasectomy, one metastasectomy or multiple local interventions), baseline factors and selection criteria for additional treatments were examined.
Osteosarcoma in One of Identical Twins: Three Cases Report and a Literature Review.
Orthop Surg
June 2021
Department of Orthopaedic Surgery, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, China.
Article Synopsis
- Osteosarcoma (OS) is a common bone cancer primarily affecting children and young adults, and it's unusual to find OS in identical twins.
- The study presents three cases of OS impacting only one twin in each pair, detailing treatments like chemotherapy and surgical reconstruction.
- The occurrence of OS in one twin provides a unique opportunity to explore the genetic factors involved in the disease, suggesting the need for ongoing monitoring of the non-affected twins for potential future developments of OS.
4 K laparoscopic total mesorectal excision for ultralow rectal cancer.
Tech Coloproctol
January 2021
Department of General Surgery, Affiliated Cancer Hospital of Zheng Zhou University, 127 DongMing Road, Zhengzhou, 450008, China.
Biological reconstruction in the treatment of extremity sarcoma in femur, tibia, and humerus.
Medicine (Baltimore)
July 2020
Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Peking University. Beijing, China, No. 31 Xin Jie Kou Dong Jie, Xi Cheng District, Beijing, China.
To understand the feasibility, clinical effect, and complications related to biological reconstruction techniques for long limb malignant bone tumors after excision.This retrospective study included eighty patients with malignant bone tumors treated at our hospital between January 2007 and January 2019. After tumor resection, 52 cases of intercalary and 28 cases of osteoarticular bone grafts were used.
View Article and Find Full Text PDFEfficacy and safety of apatinib in advanced sarcoma: an open-label, nonrandomized, single-center study of 45 patients.
Anticancer Drugs
August 2019
Bone and Soft Department, the Affiliated Cancer Hospital of Zheng Zhou University, Henan Cancer Hospital, Zhengzhou, China.
Sarcoma is a rare tumor with more than 50 histologic subtypes. Patients with advanced sarcoma have a poor prognosis. The aim of this study was to evaluate the efficacy and safety of apatinib, an oral vascular endothelial growth factor receptor-2 inhibitor, as salvage treatment for advanced bone and soft tissue sarcomas.
View Article and Find Full Text PDFEpiphysis preserving operations for the treatment of lower limb malignant bone tumors.
Eur J Surg Oncol
December 2012
He Nan Cancer Hospital, The Affiliated Cancer Hospital of Zheng Zhou University, 127 Dong Ming Road of Zheng Zhou City, He Nan Province, China.
Purpose: To assess two epiphyseal sparing procedures for the treatment of lower limb malignant bone tumors.
Methods: Between January 2007 and January 2011, 15 patients, seven males and eight females with a mean age of 11.75 years (range, 7-24), underwent epiphysis preservation operations.