568 results match your criteria: "Afferent Loop Syndrome"

Endoscopic or fluoroscopic guided naso-enteric placement for stenting and decompression has been used in mechanical enteric limb obstruction after gastrectomy or gastric bypass surgery. However, the use of double naso-enteric tube for treatment of multiple enteric limbs obstruction has not been described to date. We present a 61-year-old female with afferent limb syndrome with concomitant efferent limb obstruction which caused by kinking of anastomosis after loop gastrojejunostomy for benign gastric outlet obstruction.

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Article Synopsis
  • The study aimed to evaluate the safety, feasibility, and short-term effectiveness of λ-type esophagojejunostomy during total gastrectomy using total laparoscopy, focusing on its impact on postoperative quality of life.
  • Researchers analyzed data from 50 patients with adenocarcinoma who underwent this procedure, measuring various outcomes such as operation time, recovery times, and complications.
  • Results indicated that the procedure had manageable complications and a stable Nutritional Risk Index over 12 months, suggesting it could be a viable option for patients undergoing total gastrectomy.
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Afferent loop syndrome, sometimes referred to as afferent limb syndrome, is an infrequent mechanical complication frequently observed following foregut surgeries involving the connection of the stomach or esophagus to the jejunum. This condition is commonly found in individuals who have undergone Billroth II reconstruction following a partial gastrectomy. Here, we present the first documented case of afferent loop syndrome in a patient with a medical history involving a liver transplant due to neonatal hemochromatosis.

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Article Synopsis
  • Endoscopic ultrasound-guided gastroenterostomy is a procedure to connect the stomach with an afferent loop affected by dilation, aimed at treating afferent loop syndrome; the study assesses its effectiveness and safety.
  • The research found a 100% technical success rate and a 96% clinical success rate among 25 patients, with some serious early adverse events related to fluid leakage but no late complications.
  • The procedure demonstrated a 32% rate of recurrent intestinal obstruction after a median of 6.5 months, but was highly successful in re-interventions, confirming its overall effectiveness and safety for this condition.
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Article Synopsis
  • Afferent loop syndrome is a rare complication that can occur after upper gastrointestinal bypass surgeries, typically within two weeks, but this case shows it happened almost a decade later in a 54-year-old woman.* -
  • The patient experienced symptoms like epigastric pain, vomiting, and constipation, and tests revealed a high-grade bowel obstruction related to her previous surgeries.* -
  • She was treated conservatively with rehydration and a nasogastric tube, and was discharged after five days, highlighting the need for better guidelines on managing this syndrome after such surgeries.*
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Endoscopic ultrasound-guided gastrointestinal anastomosis: Are we there yet?

Dig Endosc

September 2024

Department of Gastroenterology, Institute of Digestive and Liver Care, S.L. Raheja Hospital, Mumbai, India.

Endoscopic ultrasound (EUS) is increasingly used as a therapeutic approach for gastrointestinal diseases, especially with the advent of lumen-apposing metal stents (LAMS). This has led to a rise in of EUS-guided gastrointestinal anastomosis procedures. Due to the reliability of intestinal conduits with LAMS, indications for EUS-guided gastrointestinal anastomosis are becoming more common and trend to potentially be standard care for gastric outlet obstruction, afferent loop syndrome, and EUS-directed transgastric interventions such as EUS-directed endoscopic retrograde cholangiopancreatography.

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Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer.

Cochrane Database Syst Rev

February 2024

Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: Choosing an optimal reconstruction method is pivotal for patients with gastric cancer undergoing distal gastrectomy. The uncut Roux-en-Y reconstruction, a variant of the conventional Roux-en-Y approach (or variant of the Billroth II reconstruction), employs uncut devices to occlude the afferent loop of the jejunum. This modification is designed to mitigate postgastrectomy syndrome and enhance long-term functional outcomes.

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Neurostimulation treatments for epilepsy: Deep brain stimulation, responsive neurostimulation and vagus nerve stimulation.

Neurotherapeutics

April 2024

Neuroscience and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

Article Synopsis
  • Epilepsy affects many people, and about one-third of those with the condition don't find relief from two standard anti-seizure medications, leading to a focus on neurostimulation options for treatment.* -
  • Neurostimulation methods like Vagus Nerve Stimulation (VNS), Deep Brain Stimulation (DBS), and Responsive Neurostimulation (RNS) are available, with some being FDA-approved and showing potential benefits in reducing seizures for patients with drug-resistant epilepsy.* -
  • The discussion highlights the effectiveness of these methods, their uses in specific populations, and their implications based on neuroimaging data, providing insights into how they target different brain areas to alleviate seizures.*
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Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) has been transformed from an innovative technique, into a viable alternative to enteral stenting and surgical gastrointestinal anastomosis for patients with gastric outlet obstruction. Even EUS-GE guided ERCP and EUS-guided gastrointestinal anastomosis for the treatment of afferent loop syndrome have been performed, giving patients more less invasive options. However, EUS-GE is still a technically challenging procedure.

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Severe malnutrition following one-anastomosis gastric bypass (OAGB) remains a concern. Fifty studies involving 49,991 patients were included in this review. In-hospital treatment for severe malnutrition was needed for 0.

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Article Synopsis
  • Afferent loop syndrome (ALS) is a rare complication after gastrointestinal surgery that requires prompt treatment, with various endoscopic interventions being explored for its management.
  • A study analyzed nine patients with malignant ALS who were treated using endoscopic methods like EMSP, EUS-EE, and EUS-HGS, focusing on success rates and patient outcomes.
  • Results indicated that all interventions were technically successful with no immediate adverse events, but stent dysfunction occurred in some cases, and most patients eventually died from their primary diseases.
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Key Clinical Message: Temporal percutaneous transhepatic duodenum drainage (PTDD) seems to be effective in the treatment of postoperative afferent loop syndrome (ALS) following transverse loop colostomy for obstructive colorectal cancer.

Abstract: Management of obstructive colorectal cancer still remains a challenge. There are various options with different risks of mortality and mobility for obstructive colorectal cancer.

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Article Synopsis
  • Endoscopic-ultrasound-guided gastrojejunostomy (EUS-GJ) using a fully covered self-expandable metal stent (FCSEMS) is being explored as a treatment for malignant afferent loop syndrome (MALS), with a focus on its effectiveness and safety.
  • A study involving 12 patients showed that both technical and clinical success in the procedure were achieved in all cases, although one patient experienced mild peritonitis as a complication.
  • Overall survival was limited, with a median of 137 days, but the findings suggest that EUS-GJ with FCSEMS is a promising option for MALS patients with a high success rate and manageable adverse effects.
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