High mean platelet volume, low-grade systemic coagulation, and fibrinolytic activation are associated with pre-term delivery and low APGAR score in intrahepatic cholestasis of pregnancy.

Objectives: This study was designed for evaluating coagulation parameters and low APGAR scores in pregnancies with intrahepatic cholestasis of pregnancy (ICP) vs. normal control pregnancies.

Methods: We carried out a prospective case-control study by enrolling 40 women with ICP at the third trimester of pregnancy and 40 pregnant women without ICP.

Is increased maternal endothelin-1 concentration associated with neonatal asphyxia and preterm delivery in intrahepatic cholestasis of pregnancy?

Objectives: To evaluate plasma endothelin-1 (ET-1) and fetuin-A concentrations in women with intrahepatic cholestasis of pregnancy (ICP) and to determine whether there is any association between these parameters and fetal asphyxia.

Methods: We carried out a prospective case-control study consisting of 32 women with ICP at third trimester of pregnancy and 32 pregnant women without ICP. Blood samples from maternal peripheral venous circulation were collected and ET-1 and fetuin-A levels were determined from the plasma samples.

The predictors of retained products of conception following first-trimester pregnancy termination with manual vacuum aspiration.

Objective: To identify the risk factors associated with retained products of conception (RPC) following first-trimester pregnancy termination with manual vacuum aspiration (MVA).

Methods: We analyzed 1623 patients who underwent MVA during the first 9 weeks of their pregnancies in SSK Aegean Obstetrics and Gynecology Teaching Hospital Department of Family Planning in between February 2001 and January 2004.

Results: A total of 81 patients (5%) had RPC after MVA.

The use of complementary and alternative medicine (CAM) therapies by Turkish women with gynecological cancer.

Purpose: To evaluate the prevalence and patterns of complementary and alternative medicine (CAM) utilization among Turkish women with gynecological cancer

Methods: In this cross-sectional study, a total of 156 patients treated between December 2002 and March 2005 at the Ministry of Health Aegean Obstetrics and Gynecology Teaching Hospital, Department of Gynecologic Oncology were evaluated. Data regarding CAM use were obtained from patients by means of face-to-face interviews.

Results: Sixty women (38.

Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study.

Objective: To compare the effectiveness of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism (IH).

Design: Prospective randomized clinical study.

Setting: Social Security Agency, Aegean Obstetrics and Gynecology Teaching Hospital, Department of Reproductive Endocrinology and Infertility, a tertiary referral center.

Development of uterine sarcoma after tamoxifen treatment for breast cancer: report of four cases.

Tamoxifen (TAM) is widely used in the treatment of breast cancer, and its paradoxical effects on female genital system are well known. During the past 10 years, many descriptions of nonepithelial uterine malignancies related to long-term TAM usage have been reported in the literature. Four uterine sarcoma patients who had history of TAM usage for previous breast cancer are presented in this study.

Prothrombin G20210A mutation in cases with recurrent miscarriage: a study of the mediterranean population.

Background: Thrombophilic predisposition may be one of the underlying causes of recurrent miscariage (RM). The purpose of this study was to evaluate the Prothrombin G20210A mutation in cases with history of RM.

Material And Methods: A total of 104 cases, 55 with diagnosis of RM and 49 control cases, were included in this controlled study.

Reproductive and obstetric characteristics of adolescent pregnancies in Turkish women.

Objective: To evaluate reproductive and obstetric characteristics of adolescent pregnancies in Turkish population.

Design: Retrospective study.

Setting: Social Security Agency (SSK) Aegean Obstetrics and Gynecology Teaching Hospital (tertiary referral center).

Pregnancy in patients with previous successful renal transplantation.

Objective: To evaluate the risk factors affecting pregnancy, perinatal outcomes, and short-term graft condition in women who underwent renal transplantation.

Method: Between May 1998 and January 2005, the histories of 20 pregnancies in 17 renal transplant recipients were reviewed retrospectively at the Ministry of Health Aegean Obstetrics and Gynecology Teaching Hospital.

Result: There were significant associations between high serum creatinine level (>1.

Necrotizing fasciitis after abdominal hysterectomy: a report on five cases.

Necrotizing fasciitis, a severe soft tissue infection, was first described 80 years ago. It occurs rarely in obstetric and gynecology practice. We reviewed medical records of 2,894 women who had underwent an abdominal hysterectomy at the Social Security Agency Aegean Obstetrics and Gynecology Teaching Hospital between 2001 and 2005, and identified 5 (0.

Comparison of pituitary-ovarian function in patients who have undergone successful renal transplantation and healthy women.

Twenty-eight renal transplantation patients, aged 19-35 years, and 30 healthy women of reproductive age were enrolled into the study. Analyses revealed significant differences between study and control groups' midluteal serum P levels and between study and control groups' serum PRL levels. Although most renal transplantation patients have plasma estrogen and gonadotropin levels similar to those in healthy women, several problems, such as luteal phase defect, might affect transplant recipients.

The feasibility and morbidity of distal pancreatectomy in extensive cytoreductive surgery for advanced epithelial ovarian cancer.

Introduction: Pancreatic metastasis of ovarian cancer is extremely rare and its therapeutic approach is not well documented. The objective of this study is to evaluate the feasibility and morbidity of pancreatic resection as a component of extensive cytoreductive surgery in epithelial ovarian cancer (EOC) patients with pancreas metastasis.

Methods: Between December 2000 and February 2003, 98 EOC patients were treated with primary cytoreduction.