Mesoporous Lanthanum-Doped Magnesium Phosphate Nanopowders Promote Healing of Critical-Size Bone Defects: An In Vivo Study.

Treating severe bone deformities and abnormalities continues to be a major clinical hurdle, necessitating the adoption of suitable materials that can actively stimulate bone regeneration. Magnesium phosphate (MP) is a material that has the ability to stimulate the growth of bones. The current study involved the synthesis of mesoporous MP and lanthanum (La)-doped nanopowders using a chemical precipitation approach.

Cancer treatment approaches within the frame of hyperthermia, drug delivery systems, and biosensors: concepts and future potentials.

This work presents a review of the therapeutic modalities and approaches for cancer treatment. A brief overview of the traditional treatment routes is presented in the introduction together with their reported side effects. A combination of the traditional approaches was reported to demonstrate an effective therapy until a few decades ago.

Organs on chips: fundamentals, bioengineering and applications.

Human body constitutes unique biological system containing specific fluid mechanics and biomechanics. Traditional cell culture techniques of 2D and 3D do not recapitulate these specific natures of the human system. In addition, they lack the spatiotemporal conditions of representing the cells.

Generation of cardiomyocytes from stem cells cultured on nanofibrous scaffold: Experimental approach for attenuation of myocardial infarction.

The current study was constructed to fabricate polyamide based nanofibrous scaffolds (NS) and to define the most promising one for the generation of cardiomyocytes from adipose tissue derived mesenchymal stem cells (ADMSCs). This purpose was extended to assess the potentiality of the generated cardiomyocytes in relieving myocardial infarction (MI) in rats. Production and characterization of NSs were carried out.

Comparative Study of (Bottlebrush) and (Pomegranate) Extracts for Sustainable Synthesis of Silver Nanoparticles and Their Oral Antimicrobial Efficacy.

A comparative study was applied to investigate the potential of (bottlebrush) flower extract (BBE) and (pomegranate) peel extracts (PPE) for the sustainable synthesis of the silver nanoparticles, Ag-BBE and Ag-PPE, respectively. The synthesis process of Ag NPs using the selected extracts was applied under optimized conditions. Hence, the effect of the selected plant's type on the different characteristics of the synthesized green Ag NPs was investigated.

Synthesis, structural, molecular docking, and in vitro biological activities of Cu-doped ZnO nanomaterials.

Copper-doped ZnO nanoparticles with the formula ZnO, where x = 0.0, 0.03, 0.

Fast skin healing chitosan/PEO hydrogels: In vitro and in vivo studies.

Due to its outstanding qualities, particularly when it takes the shape of hydrogels, chitosan is a well-known biological macromolecule with many applications. When chitosan hydrogels are modified with other polymers, the desirable function as skin regeneration hydrogels is compromised; nevertheless, the mechanical properties can be improved, which is crucial for commercialization. In this study, for the first time, bimetallic zinc silver metal-organic frameworks (ZAg MOF) loaded with ascorbic acid were added to chitosan/polyethylene oxide (PEO) based interpenetrating polymer network (IPN) hydrogels that were crosslinked with biotin to improve their antimicrobial activity, mechanical characteristics, and sustainable treatment of wounds.

Structural, dielectric, and antimicrobial evaluation of PMMA/CeO for optoelectronic devices.

In the current report, we have successfully synthesized nanocomposites of PMMA incorporating different doping of CeO through a chemical approach. XRD results reflects decent matching for CeO nanoparticles with 29 nm crystallite size. FTIR spectroscopy demonstrates the characteristic functional groups validating the successful formation of the composite.

A comparative study on the antifungal effect of potassium sorbate, chitosan, and nano-chitosan against and in skim milk acid-coagulated (Karish) cheese.

Background And Aim: Yeasts are common contaminants in the cheese industry, which frequently arise from raw milk, the surrounding environment, and equipment, resulting in economic losses in addition to health hazards. This study aimed to compare the antifungal effect of chitosan and nano-chitosan as natural preservatives with a commonly used chemical preservative (potassium sorbate) against and .

Materials And Methods: Laboratory Karish cheese was manufactured with the addition of potassium sorbate, chitosan, nano-chitosan, and their combinations at different concentrations.

Dye removal membrane from electrospun nanofibers of blended polybutylenesuccinate and sulphonated expanded polystyrene waste.

Polystyrene (PS) is a thermoplastic polymer used in food packaging and the manufacture of trays and cups, among other applications. In this work, the preparation of a membrane by electrospinning blended sulphonated expanded PS waste and polybutylenesuccinate (PBS) is described. The fiber quality is controlled by selecting the right polymers' ratios and solvents.

Photodetection Properties of CdS/Si Heterojunction Prepared by Pulsed Laser Ablation in DMSO Solution for Optoelectronic Application.

The high-quality n-type CdS on a p-type Si (111) photodetector device was prepared for the first time by a one-pot method based on an ns laser ablation method in a liquid medium. Cadmium target was ablated in DMSO solution, containing sulfur precursor, and stirred, assisting in 1D-growth, to create the sulfide structure as CdS nano-ropes form, followed by depositing on the Si-substrate by spin coating. The morphological, structural, and optical characteristics of the CdS structure were examined using X-ray diffraction, transmission, and scanning electron microscopy, photoluminescence, and UV-VIS spectroscopy.

Prebiotic-mediated gastroprotective potentials of three bacterial levans through NF-κB-modulation and upregulation of systemic IL-17A.

This study aimed to investigate whether the gastroprotective effects of three types of bacterial levans are correlated with their prebiotic-associated anti-inflammatory/antioxidant potentials. Three levans designated as LevAE, LevP, and LevZ were prepared from bacterial honey isolates; purified, and characterized using TLC, NMR, and FTIR. The anti-inflammatory properties of levan preparations were assessed in LPS-stimulated RAW 264.

Effect of CuO Nanoparticles on the Optical, Structural, and Electrical Properties in the PMMA/PVDF Nanocomposite.

A polymeric nanocomposite film, composed of PMMA/PVDF and different amounts of CuO NPs, was successfully prepared using the casting method to enhance its electrical conductivity. Various techniques were employed to investigate their physicochemical properties. The addition of CuO NPs causes a noticeable difference in the intensities and locations of vibrational peaks in all bands, confirming the incorporation of CuO NPs inside the PVDF/PMMA.

Strength and bioactivity of PEEK composites containing multiwalled carbon nanotubes and bioactive glass.

Unlabelled: Polyetheretherketone (PEEK) polymer is a widely accepted implantable biomaterial in the biomedical field. However, PEEK has a low elastic modulus (E-modulus) as well as a bio-inert nature which is not conductive to rapid bone cell attachment, hence, producing delayed or weak bone-implant integration. Multiwalled carbon nanotubes (MWCNTs) represent one of the strongest known materials that could be added to a polymer to improve its mechanical properties.

Boosting selectivity towards formate production using CuAl alloy nanowires by altering the CO reduction reaction pathway.

Understanding the fundamentals behind an electrocatalyst's selectivity enables the ability to steer product formation. Herein, we study Cu nanowires doped with a small amount of Al (12%) for COR, which enhances formate production by 16.9% over pure Cu nanowires.

Biphasic calcium phosphate doped with zirconia nanoparticles for reconstruction of induced mandibular defects in dogs: cone-beam computed tomographic and histopathologic evaluation.

The present study aimed to evaluate osteogenic potential and biocompatibility of combining biphasic calcium phosphate with zirconia nanoparticles (4Zr TCP/HA) compared to biphasic calcium phosphate (TCP/HA) for reconstruction of induced mandibular defects in dog model. TCP/HA and 4Zr TCP/HA scaffolds were prepared. Morphological, physicochemical, antibacterial, cytocompatibility characterization were tested.

Metal-based-oxide nanoparticles assisted the culture growth of as micronutrients: essential metabolic processes and genetic stability.

The present study evaluates the culture growth rate of upon using nano metal-based-oxides such as hematite (FeO NPs), zinc oxide (ZnO NPs), and manganese oxide (MnO NPs) nanoparticles as analogues of three primary micronutrients such as iron (Fe), zinc (Zn), and manganese (Mn), which exist in soil as micronutrients. Herein, the culture growth rate was investigated using three different concentrations (, 20, 40, and 60 mg L) of as-prepared metal oxide nanoparticles compared to the control. In addition, the as-prepared nanoparticles have been prepared the co-precipitation method.

Formulation and evaluation of alginate-gelatin hydrogel scaffolds loaded with zinc-doped hydroxyapatite and 5-fluorouracil.

Alginate and gelatin are natural macromolecules used to formulate biocompatible drug delivery systems. Hydroxyapatite (HA) is an osteophilic ceramic used to prepare bone scaffolds. The current study aimed at preparing and characterizing HA, zinc-doped HA, and 5-fluorouracil(5-FU)-loaded alginate-gelatin-based hydrogel scaffolds using different crosslinking solutions.

Antiviral Electrospun Polyamide Three-Layered Mask Filter Containing Metal Oxide Nanoparticles and Black Seed Oil.

Upon the tremendous spread of coronavirus, there is a need to develop biodegradable, multifunctional, antiviral masks that can be safely used without polluting the environment as conventional surgical masks do. In this study, a three-layered mask filter is designed and fabricated. The first two layers contain electrospun polyamide with dispersed nanoparticles (NPs) of TiO and ZnO prepared via breakdown anodization.

Photocatalytic Performance Improvement by Doping Ag on ZnO/MWCNTs Nanocomposite Prepared with Pulsed Laser Ablation Method Based Photocatalysts Degrading Rhodamine B Organic Pollutant Dye.

ZnO/MWCNTs nanocomposite has significant potential in photocatalytic and environmental treatment. Unfortunately, its photocatalytic efficacy is not high enough due to its poor light absorbance and quick recombination of photo-generated carriers, which might be improved by incorporation with noble metal nanoparticles. Herein, Ag-doped ZnO/MWCNTs nanocomposite was prepared using a pulsed laser ablation approach in the liquid media and examined as a degradable catalyst for Rhodamine B.

Osteogenic potential of calcium silicate-doped iron oxide nanoparticles versus calcium silicate for reconstruction of critical-sized mandibular defects: An experimental study in dog model.

Objective: To evaluate bioactivity and osteogenic potential of calcium silicate (CS)-doped iron oxide (FeO) nanoparticles versus pure CS in the reconstruction of induced critical-sized mandibular defects.

Design: CS-doped FeO was prepared; morphological and microstructure identification of nanoparticles were made. An randomised design was developed on 24 adult male dogs where four critical-sized mandibular defects were created in each dog.

Neuroprotective Potential of Intranasally Delivered Sulforaphane-Loaded Iron Oxide Nanoparticles Against Cisplatin-Induced Neurotoxicity.

Cisplatin (CIS) is a platinum-based chemotherapeutic drug that is widely used to treat cancer. However, its therapeutic efficiency is limited due to its potential to provoke neurotoxicity. Sulforaphane (SF) is a natural phytochemical that demonstrated several protective activities.

Ag/ZnO Thin Film Nanocomposite Membrane Prepared by Laser-Assisted Method for Catalytic Degradation of 4-Nitrophenol.

Zinc oxide thin film (ZnO thin film) and a silver-doped zinc oxide nanocomposite thin film (Ag/ZnO thin film) were prepared by the technique of the pulsed laser deposition at 600 °C to be applicable as a portable catalytic material for the removal of 4-nitrophenol. The nanocomposite was prepared by making the deposition of the two targets (Zn and Ag), and it was analyzed by different techniques. According to the XRD pattern, the hexagonal wurtzite crystalline form of Ag-doped ZnO NPs suggested that the samples were polycrystalline.

Removal of Ni(II) Ions by Poly(Vinyl Alcohol)/AlO Nanocomposite Film via Laser Ablation in Liquid.

AlO-poly(vinyl alcohol) nanocomposite (AlO-PVA nanocomposite) was generated in a single step using an -friendly method based on the pulsed laser ablation approach immersed in PVA solution to be applicable for the removal of Ni(II) from aqueous solution, followed by making a physicochemical characterization by SEM, XRD, FT-IR, and EDX. After that, the effect of adsorption parameters, such as pH, contact time, initial concentration of Ni(II), and medium temperature, were investigated for removal Ni(II) ions. The results showed that the adsorption was increased when pH was 5.