Development of Composite Semiconductor Films Based on Organotin Complexes Doped with Cobalt Porphine for Applications in Organic Diodes.

In this work, we present the green synthesis of complex - derived from β-hidroxymethylidene indanones by ultrasound, which allowed for the obtaining of compounds in a shorter time and with good yields. These organotin complexes were then doped with cobalt porphine and incorporated into a poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) matrix to manufacture composite semiconductor films. The semiconductor films were characterized through atomic force microscopy, examining their topography, Knoop hardness (around 17 HK), and tensile strength, which varied from 5 × 10 to 7 × 10 Pa.

Drivers of Seasonal Change of Avian Communities in Urban Parks and Cemeteries of Latin America.

Urban parks and cemeteries constitute hot spots of bird diversity in urban areas. However, the seasonal dynamics of their bird communities have been scarcely explored at large scales. This study aims to analyze the drivers of urban bird assemblage seasonality in urban parks and cemeteries comparing assemblages during breeding and non-breeding seasons in the Neotropical Region.

Gut-brain Axis and Irritable Bowel Syndrome During the Lockdown due to the SARS-CoV-2 Pandemic: A Survey-based Study.

Background: Irritable bowel syndrome (IBS) is influenced by various factors, including socioemotional stressors. The COVID-19 lockdown created a unique environment characterized by reduced social interactions, potentially impacting IBS symptoms.

Aim: To assess how lockdown measures affected symptoms related to the gut-brain axis in IBS patients in Buenos Aires, Argentina.

Association of Pedagogical Training with the Social Skills of Medical Tutors in Problem-Based Learning Curriculum.

Background: Satisfactory interaction between tutor and student is fundamental to the success of problem-based learning, and social skills (SS) are essential in this context. The factors associated with a better repertoire of teachers' SS are still unclear. Therefore, we aimed to assess tutors' SS and investigate which factors might be related to a better repertoire of SS.

Impact of NPK fertilization on the metabolomic profile and nutritional quality of Portulaca oleracea L. using nuclear magnetic resonance analysis.

Purslane is a plant with high nutritional content that is mainly produced in the central part of Mexico. The nutritional content of purslane depends on various factors such as climatic and soil conditions, phenology, and fertilization. This article describes the H NMR metabolomics profiling of purslane in relation to fertilization at two harvest stages: C and C (27 and 42 days after emergence).

Cognitive impairment at older ages among 8000 men and women living in Mexico City: a cross-sectional analyses of a prospective study.

Background: There is limited population-based evidence on the prevalence of cognitive impairment in Mexico, a country with a rapidly aging population and where key risk factors, such as diabetes and obesity, are common. This study describes the distribution of cognitive impairment in adults from Mexico City.

Methods: This cross-sectional population-based study included participants from the Mexico City Prospective Study which recruited 150,000 adults aged ≥ 35 years in 1998-2004.

A chemometric approach to the interaction of hydrogen peroxide and thermally activated persulfate in the removal of aromatic compounds.

This study evaluates the combined use of H₂O₂ and thermally activated S₂O₈⁻ (T-PDS) for the degradation of phenolic compounds (PhOH) in wastewater, aiming to limit or eliminate sludge production. Phenolic compounds are common in industrial effluents, and their effective removal is crucial for reducing environmental impact. The study employs Response Surface Methodology (RSM) and Principal Component Analysis (PCA) to optimise critical variables such as temperature, pH, and oxidant concentrations.

Neural mass modeling for the masses: Democratizing access to whole-brain biophysical modeling with FastDMF.

Different whole-brain computational models have been recently developed to investigate hypotheses related to brain mechanisms. Among these, the Dynamic Mean Field (DMF) model is particularly attractive, combining a biophysically realistic model that is scaled up via a mean-field approach and multimodal imaging data. However, an important barrier to the widespread usage of the DMF model is that current implementations are computationally expensive, supporting only simulations on brain parcellations that consider less than 100 brain regions.

FAST functional connectivity implicates P300 connectivity in working memory deficits in Alzheimer's disease.

Measuring transient functional connectivity is an important challenge in electroencephalogram (EEG) research. Here, the rich potential for insightful, discriminative information of brain activity offered by high-temporal resolution is confounded by the inherent noise of the medium and the spurious nature of correlations computed over short temporal windows. We propose a methodology to overcome these problems called filter average short-term (FAST) functional connectivity.

On the effectiveness of the red alga Laurencia microcladia as a PAH biomonitor in coastal marine ecosystems.

Anthropogenic pressures affect large stretches of Mediterranean coastal environments, determining alterations, including chemical pollution, able to impair ecosystem functioning and services. Among the pollutants of major concern for their toxicity and persistence, there are polycyclic aromatic hydrocarbons (PAHs), which can be effectively monitored through bioaccumulation approaches. However, the main biomonitor of PAHs in the Mediterranean Sea, Posidonia oceanica, is currently undergoing extensive regressions due to anthropogenic pressures, forcing the search for alternative biomonitors.

Structural inequality linked to brain volume and network dynamics in aging and dementia across the Americas.

Structural inequality, the uneven distribution of resources and opportunities, influences health outcomes. However, the biological embedding of structural inequality in aging and dementia, especially among underrepresented populations, is unclear. We examined the association between structural inequality (country-level and state-level Gini indices) and brain volume and connectivity in 2,135 healthy controls, and individuals with Alzheimer's disease and frontotemporal lobe degeneration from Latin America and the United States.

Neural dynamics of social verb processing: an MEG study.

Human vocabularies include specific words to communicate interpersonal behaviors, a core linguistic function mainly afforded by social verbs (SVs). This skill has been proposed to engage dedicated systems subserving social knowledge. Yet, neurocognitive evidence is scarce, and no study has examined spectro-temporal and spatial signatures of SV access.

Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations.

Efforts to prevent dementia can benefit from precision interventions delivered to the right population at the right time; that is, when the potential to reduce risk is the highest. Young adults (aged 18-39 years) are a neglected population in dementia research and policy making despite being highly exposed to several known modifiable risk factors. The risk and protective factors that have the biggest effect on dementia outcomes in young adulthood, and how these associations differ across regions and groups, still remain unclear.

Cannabidiol induces autophagy via CB receptor and reduces α-synuclein cytosolic levels.

Numerous studies have explored the role of cannabinoids in neurological conditions, chronic pain and neurodegenerative diseases. Restoring autophagy has been proposed as a potential target for the treatment of neurodegenerative diseases. In our study, we used a neuroblastoma cell line that overexpresses wild-type α-synuclein to investigate the effects of cannabidiol on autophagy modulation and reduction in the level of cytosolic α-synuclein.

The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance.

Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health.

Global impact of ten-valent and 13-valent pneumococcal conjugate vaccines on invasive pneumococcal disease in all ages (the PSERENADE project): a global surveillance analysis.

Background: Pneumococcal conjugate vaccines (PCVs) that are ten-valent (PCV10) and 13-valent (PCV13) became available in 2010. We evaluated their global impact on invasive pneumococcal disease (IPD) incidence in all ages.

Methods: Serotype-specific IPD cases and population denominators were obtained directly from surveillance sites using PCV10 or PCV13 in their national immunisation programmes and with a primary series uptake of at least 50%.

The Impact of Leader-Member Relationships on Team Effectiveness Through Speaking Up and Silence: A Cross-Sectional Study in Rural Chinese Hospitals.

Introduction: Although the importance of leader-member relationships in teamwork is acknowledged in literature, a deeper understanding of this relationship is lacking, especially in rural areas. The impact of leader-member relationships on team outcomes is especially important in rural Chinese hospitals as improving teamwork forms a national health reform priority in these hospitals. This study investigates how leader-member relationships (ie leader-member perceived similarity and power distance orientation) influence team outcomes (ie perceived quality of care and job satisfaction) via speaking up and silence.

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein.

Virus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus, which contain envelope glycoproteins E1-E2 and capsid, exhibit an architecture that closely resembles native virus. In contrast to monomeric and soluble envelope 2 (E2) glycoprotein, both VLPs as well as the adenovirus and modified vaccinia virus Ankara (MVA) vaccine platforms expressing the equivalent envelope glycoproteins E1-E2, and capsid induced highly neutralising antibodies after immunisation.

Making dew in the Atacama Desert: a paradigmatic case of plant water uptake water from an unsaturated atmosphere fails a test.

Background And Aims: Nolana mollis is a dominant plant species in the hyperarid Atacama Desert. A previous hypothesis states that N. mollis owes its success to the condensation of atmospheric water from undersaturated air onto its leaf surfaces by exuded salts, and absorption of this water by its leaves, or by shallow roots following drip onto the soil surface; living roots of N.

Comprehensive Analysis of Bioactive Compounds, Functional Properties, and Applications of Broccoli By-Products.

Broccoli by-products, traditionally considered inedible, possess a comprehensive nutritional and functional profile. These by-products are abundant in glucosinolates, particularly glucoraphanin, and sulforaphane, an isothiocyanate renowned for its potent antioxidant and anticarcinogenic properties. Broccoli leaves are a significant source of phenolic compounds, including kaempferol and quercetin, as well as pigments, vitamins, and essential minerals.

A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1.

Myotonic dystrophy type 1 (DM1) is an autosomal dominant disorder clinically characterized by progressive muscular weakness and multisystem degeneration, which correlates with the size of CTG expansion and MBLN decrease. These changes induce a calcium and redox homeostasis imbalance in several models that recapitulate the features of premature tissue aging. In this study, we characterized the impact of a new family of FKBP12 ligands (generically named MPs or MP compounds) designed to stabilize FKBP12 binding to the ryanodine receptors and normalize calcium dysregulation under oxidative stress.

Assessment of Greenhouse Gas Emissions and Carbon Sequestration in Dairy Goat Farming Systems in Northern Extremadura, Spain.

Livestock farming is an activity closely linked to the environment, directly affecting its surrounding ecosystem while utilizing the natural resources it provides. Accordingly, it is essential to study these production systems in order to implement more sustainable models that allow for a balance between socioeconomic and environmental factors. The main objective of this study was to analyze the environmental impact of nine different dairy goat production systems located in northern Extremadura, Spain.

Brain health is essential for smooth economic transitions: towards socio-economic sustainability, productivity and well-being.

Optimal brain health is essential to smoothing major global skill-intensive economic transitions, such as the bioeconomy, green, care economy and digital transitions. Good brain health is vital to socio-economic sustainability, productivity and well-being. The care transition focuses on recognizing and investing in care services and care work as essential for economic growth and social well-being.

Take it sitting down: the effect of body posture on cortical potentials during free viewing-A mobile EEG recording study.

Brain imaging performed in natural settings is known as mobile brain and body imaging (MoBI). One of the features which distinguishes MoBI and laboratory-based experiments is the body posture. Previous studies pointed to mechanical, autonomic, cortical and cognitive differences between upright stance and sitting or reclining.