Application of Anatomically Designed 2-Dimensional V Plate in Management of Mandible Fracture: A Pilot Study.

Background: Mandible is the only mobile facial jaw bone and it aides in various functions such as phonation and mastication. Therefore, management of mandible fracture becomes inevitable due to its functional and anatomical importance. Fracture fixation methods and techniques have steadily evolved with various osteosynthesis systems.

Effectiveness of Leg Raise and Leg Fold Maneuver to Prevent Syncope During Extraction of Teeth: A Pilot Study.

Objectives The primary objective of this study is to evaluate the effectiveness of leg raise and leg fold maneuvers to prevent syncope during extraction procedures. Methods This study included 30 patients with a previous history of syncope and dental anxiety. Patients were randomly divided into two groups consisting of 15 patients each.

In Silico Molecular Docking Studies of Phytocompounds From Coleus Amboinicus Against Glucokinase.

Diabetes is one of the most prevalent metabolic illnesses that can be fatal, and it is the ninth-largest cause of mortality worldwide. Even though there are effective hypoglycemic medications available for the treatment of diabetes, researchers continue to look for a medication that is more effective and has fewer adverse effects by focusing on various metabolic components such as enzymes, transporters, receptors. The enzyme Glucokinase (GCK), which is present mainly in the liver and beta cells of the pancreas, is involved in maintaining blood glucose homeostasis.

Expression of Matrix Metalloproteinase-21 in Oral Squamous Cell Carcinoma.

Introduction Oral squamous cell carcinoma (OSCC) is one of the most common cancer with increasing morbidity and mortality due to regional invasion, metastasis, and secondary malignancy along with associated medical complications. The degradation of matrix metalloproteinases (MMPs) is essential for the progression of carcinoma, hence MMPs are implicated in cancer invasion and metastasis as a biomarker. Objective The primary objective of this study was to find the expression of MMP-21 between oral squamous cell carcinoma and healthy tissue.

Designing Novel Multi-Epitope Vaccine Construct against -Interpain A: An Immunoinformatics Approach.

: Periodontitis is a chronic multifactorial inflammatory infectious disease marked by continuous degradation of teeth and surrounding parts. One of the most important periodontal pathogens is , and with its interpain A proteinase, it leads to an increase in lethal infection. : The current study was designed to create a multi-epitope vaccine using an immunoinformatics method that targets the interpain A of .

Is extracorporeal plating ideal for condylar fracture? A case report with a two-year follow-up study.

Management of condylar fractures includes the closed and open methods. The closed method, although is conservative, has disadvantages such as inadequate reduction, disturbances in occlusion, and a decrease in ramal height. To overcome these disadvantages, surgeons prefer open reduction and internal fixation.

Monocyte-to-High-density Lipoprotein Cholesterol Ratio as a Novel Inflammatory Marker in Periodontal Disease: A Pilot Study.

Aim: The monocyte-to-high-density lipoprotein cholesterol ratio (MHR) has currently been proposed as an indicator of inflammation. The aim of the present study was to assess the relationship between the monocyte-to-high-density lipoprotein cholesterol ratio and periodontal health and disease.

Materials And Methods: A total of 90 patients were selected for the study - 30 healthy patients (group I) and 60 periodontitis patients (groups II and III).

Evaluation of Reactive Oxygen Metabolites, Resistin, and Red Complex Bacteria in Obese Subjects with or without Periodontitis.

Aim: The study's aim was to assess and compare the clinical parameters, plasma reactive oxygen metabolites (ROM) levels, gingival crevicular fluid (GCF) resistin, serum resistin values, and red complex bacteria in obese or overweight subjects with and without periodontitis and also to determine the effect of non-surgical periodontal therapy (NSPT) on plasma ROM, serum, and GCF resistin values in obese or overweight subjects with chronic periodontitis.

Material And Methods: A total of 160 subjects were recruited and designated into four groups with 40 subjects each as group I - obese with chronic periodontitis; group II - normal weight subjects with chronic periodontitis; group III - obese subjects with healthy periodontium; and group IV - normal weight subjects with healthy periodontium. The periodontal parameters, plasma ROM, GCF resistin and serum resistin, and red complex bacteria levels were estimated at baseline.

Association of MICA gene Exon-5 polymorphism in oral submucous fibrosis.

Objective: The present study was conducted to explore the allele frequencies of MICA gene Exon-5 transmembrane and to measure the circulatory MICA levels in various histologic grades of patients with oral submucous fibrosis (OSF) compared to healthy individuals.

Study Design: We enrolled a total of 595 patients for this cross-sectional study and divided them into 2 groups: healthy controls (n = 320) and patients with OSF (n = 275). Further, patients with OSF were subdivided based on their histologic gradings.

Randomized Controlled Study on Effect of Concentrated Growth Factors on Crestal Bone Levels and Peri-implant Bone Density in Dental Implants.

Introduction: Modern dentistry aims to restore the comfort and health of the stomatognathic system. Dental implants have emerged as a promising option for this purpose. Concentrated growth factors (CGFs) have been suggested to enhance the healing of bone grafts and enhance the integration of implants into the bone.

Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India.

Background: There is a need to monitor the fluoride content of dentifrices used for children in a country like India, where there is prevalence of endemic fluorosis.

Aim: To evaluate the fluoride content of dentifrices for children available in India.

Settings And Design: study in a laboratory setting.

Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An Study.

Context: Disinfection of the root canal system by biomechanical preparation and profuse irrigation is especially important in primary teeth due to its complex pulp canal anatomy. Appropriate selection of irrigating solution should be done in terms of tissue dissolving capacity, antibacterial efficacy, and palatability when treating pediatric cases.

Aim: The aim of the study was to compare the antibacterial efficacy of 2% chlorhexidine (CHX), 0.

Study - Comparative Evaluation of Bond Strengths of Stainless Steel Brackets and Ceramic Brackets after Curing with the Argon Laser and the Conventional Visible Light.

Aim: The purpose of this study was to compare the bond strengths of stainless steel brackets and ceramic brackets after treated with conventional visible light and argon laser.

Methodology: Extracted 80 human premolar teeth were collected and stored in distilled water. They are classified into four groups.

Stature Prediction by Comparing Maxillary and Mandibular Intercanine Width and Intermolar Width among Tamil Nadu Population.

Background: Teeth are one of the strongest hard tissues that can resist a variety of antemortem and postmortem insults and an important evidence in the field of medicolegal and forensics. In the identification of unknown human remains of the deceased, stature estimation is a preliminary investigation. Previously, the comparison of osteometry with odontometry in stature determination has been made.

Sealing Ability of Obturation with Different Sealers Applied Over Apically Separated Rotary File - Retrograde Bacterial Leakage Study.

Background And Aims: . Retrieval of separated rotary file may not be possible many times. Then sealing of coronal root canal system depends on sealing ability of root canal sealers.

Assessment of Knowledge, Awareness, and Perception of Platelet-Rich Plasma among Oral Surgeons.

Aim: The current survey was conducted to assess the knowledge and awareness of platelet-rich plasma (PRP) among oral surgeons in the state of Tamil Nadu.

Methodology: The cross-sectional questionnaire survey was conducted among oral surgeons in the state of Tamil Nadu. The self-administered questions related to knowledge and awareness of PRP were collected from 500 participants.

Prevalence of among Denture Wearers and Nondenture Wearers.

Introduction: A denture wearer is highly prone to develop -associated denture stomatitis (CADS) due to the conversion of the normal oral commensal spp. into a pathogen under favorable conditions. Immuno-compromised status, trauma from the prosthesis, other systemic conditions, and improper maintenance of the dentures by the patient are few of the causative agents which turn the oral balance into an unhealthy and unsuitable foundation for the wearing of the prosthesis.

Mylohyoid Ridge as a Predictor of Available Bone for Implant Placement: A Cone-Beam Computed Tomography (CBCT) Retrospective Observational Study.

Introduction: The posterior mandibular region, due to the presence of vital structures, poses a high risk during implant placement because of its susceptibility to neurovascular injury and perforation of the lingual cortex. A breach in implant length and available bone height may lead to serious intraoperative and postoperative complications. Prediction of the exact location of the inferior alveolar nerve and submandibular fossa anatomy is a prerequisite for ideal implant placement, which is always not possible with conventional radiographic and clinical techniques.

Intraoral malignant glomus tumor.

Glomus tumors are uncommon, benign solitary tumors derived from the glomus apparatus. We report here a case of a malignant glomus tumor in an 8-year-old child presenting as a multilocular ill-defined radiolucency of the mandible. The lesion microscopically showed sheets of round basophilic cells with high nuclear-cytoplasmic ratio, indistinct cell boundaries, nuclear hyperchromatism and nuclear pleomorphism.

Comparative Assessment of Qmix as Endodontic Irrigant on Reversal of Bond Strength in Teeth Subjected to Irradiation: An Scanning Electron Microscope Study.

Aim: The aim of this current study was to compare and evaluate the reversal efficacy of Qmix and chitosan-based irrigation materials quantitatively through the assessment of the push-out bond strength of bioceramic sealer employing universal testing machine and to qualitatively analyze the sealer/dentin interface by scanning electron microscope (SEM) in the teeth subjected to fractioned radiation.

Materials And Methods: Ninety single-rooted straight human maxillary central incisors were randomly divided into six groups ( = 15) where in three groups comprise Chitosan, Qmix, and EDTA/sodium hypochlorite which were not exposed to irradiation while other three groups were challenged with irradiation protocols. Root canals were prepared with ProTaper universal system and all the samples were irrigated according to the final irrigation protocols and obturated with bioceramic sealers.

Evaluation of Systemic Markers Related to Anemia in Aggressive Periodontitis Patients before and after Phase I Periodontal Therapy: An Interventional Study.

Aim: The main aim of the study was to evaluate the systemic markers related to anemia in generalized aggressive periodontitis (GAgP) patients before and after phase I therapy.

Materials And Methods: Based on the inclusion criteria, 15 patients with GAgP were allocated to two groups, group A (before phase I periodontal therapy) and group B (after phase I periodontal therapy). After 3 months, clinical parameters and hematological parameters were reevaluated.

Immunohistochemical expression and evaluation of cyclin D1 and minichromosome maintenance 2 in oral squamous cell carcinoma and verrucous carcinoma.

Background: The study of cell proliferation is important for assessing the tumor behavior, prognosis and patient survival of oral carcinomas. As literature search did not reveal sufficient studies of immunohistochemical expression of cyclin D1 and minichromosome maintenance 2 (MCM2) in oral squamous cell carcinoma (OSCC) and verrucous carcinoma (VC), the present study was undertaken.

Materials And Methods: The study group included 20 cases of histopathologically diagnosed OSCC, 10 cases of VC and 10 cases of normal mucosa (NM).

Gene Interaction Network Analysis Reveals IFI44L as a Drug Target in Rheumatoid Arthritis and Periodontitis.

Objective: Despite extensive research on periodontitis and rheumatoid arthritis, the underlying molecular connectivity between these condition remains largely unknown. This research aimed to integrate periodontitis and rheumatoid arthritis gene expression profiles to identify interconnecting genes and focus to develop a common lead molecule against these inflammatory conditions.

Materials And Methods: Differentially expressed genes (DEGs) of periodontitis and rheumatoid arthritis were identified from the datasets retrieved from the Gene Expression Omnibus database.

Ethnic-Guided Soft Tissue Cephalometric Analysis on Lambani Indian Inhabitants for Forensic Facial Reconstruction.

Background: Forensic craniofacial reconstruction is a combination of both scientific technique and artistic skill that assist facial soft tissue approximation on the skull to obtain an image of an individual that varies in the different ethnic groups depending on genetic and environmental factors such as soft tissue norms.

Objectives: The present study was aimed to evaluate the soft tissue norms for Lambani Indian tribes spread across the state of Karnataka in India and compare them with the local inherent ethnolinguistic Kannadiga population.

Material And Methods: Forty healthy individuals encompassing 20 Lambanis and 20 Kannadigas were selected using demographic information.