2 results match your criteria: "Addenbrooke's Hospital B289[Affiliation]"
Hepatic lipodystrophy of Galloway calves.
Vet Rec
September 2015
SRUC St Boswells, Greycrook, St Boswells, Roxburghshire TD6 0EU.
Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recycling.
Diabetologia
May 2011
University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital B289, Cambridge, CB2 0QR, UK.
Aims/hypothesis: Genetic insulin receptoropathies are a rare cause of severe insulin resistance. We identified the Ile119Met missense mutation in the insulin receptor INSR gene, previously reported in a Yemeni kindred, in four unrelated patients with Somali ancestry. We aimed to investigate a possible genetic founder effect, and to study the mechanism of loss of function of the mutant receptor.
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