5,426 results match your criteria: "Acute Laryngitis"

Anakinra in relapsing polychondritis: a case report and review of the literature.

Immunotherapy

December 2024

Department of Clinical Immunology and Allergy, Flinders Medical Centre, Bedford Park, South Australia.

Relapsing polychondritis is rare and affects non-synovial fibrocartilage. Currently, there is a paucity of treatment algorithms, especially for those with refractory disease. A middle-aged man presented with polychondritis affecting the nose, ears, joints, and larynx.

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A 9.5-year-old male neutered domestic short-haired cat received two courses of postoperative, definitive-intent conformal radiation therapy (RT) for recurrent laryngeal adenocarcinoma (LACA). Adjuvant RT was prescribed (16 × 3.

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Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS).

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Hereditary angioedema in children: Review and practical perspective for clinical management.

Pediatr Allergy Immunol

December 2024

French National Reference Center for Angioedema (CREAK), Center of Excellence and Reference (ACARE), Internal Medicine Department, Grenoble Alpes University Hospital, Grenoble, France.

Background: Hereditary angioedema (HAE) in children has specific features and requires multidisciplinary management.

Methods: We performed a literature search and underwent in-depth discussions to provide practical tools for physicians.

Results: HAE is a rare, life-threatening genetic disorder.

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Clinical and swallowing characteristics of tracheostomized patients with post-intubation acquired tracheal or laryngotracheal stenosis.

Clinics (Sao Paulo)

December 2024

Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address:

Article Synopsis
  • The study examined patients with tracheal or laryngotracheal stenosis who required tracheostomy, focusing on their swallowing and clinical profiles before undergoing airway interventions.
  • It involved a retrospective cohort study where patients underwent swallowing evaluations and imaging, with follow-ups at 6 and 12 months to assess progress.
  • Results showed female predominance, high rates of subglottic stenosis, and that many had significant swallowing difficulties, indicating a need for personalized care due to potential complications affecting recovery.
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Introduction: Vocal cord dysfunction (VCD) is a complex disorder characterized by episodic adduction of the vocal folds during inspiration and expiration, which can lead to dyspnea, wheezing, cough, and acute-onset respiratory distress. Currently, there is a lack of standardized criteria among treating physicians across multiple disciplines, including otolaryngologists, pulmonologists, allergists, and speech and language pathologists, for diagnosis and treatment of VCD, although laryngeal-respiratory retraining therapy (LRT) has emerged as the preferred treatment modality.

Objective: In the present study, we examined the efficacy of LRT in patients presenting with a clinical diagnosis of VCD in the presence and absence of laryngeal adduction on laryngoscopy.

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Background Thyroid surgeries have become so common that they are performed for both benign and malignant conditions of the thyroid. However, hypoparathyroidism and recurrent laryngeal nerve (RLN) injury may turn out to be a nightmare, complicating the surgical outcome. This study will, therefore, attempt to assess the complications related to different types of thyroid surgeries in order to identify the risk factors involved.

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Chemical Laryngitis Following Periprocedural Emesis.

J Voice

November 2024

Sean Parker Institute for the Voice, Department of Otolaryngology - Head and Neck Surgery, Weill Cornell Medicine, New York, NY.

Although emesis is a relatively common event that bathes the larynx in low pH and irritative enzymes, prolonged laryngeal consequences of emesis are atypical. We present three cases of laryngeal injury of unusual severity and duration from periprocedural emesis and discuss predisposing factors, acute management, and mitigation of sequalae.

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Article Synopsis
  • - The COVID-19 pandemic has led to a significant rise in cases of acute pharyngitis (AP), and the study focuses on the medicinal properties of Tinosporae Radix (TR) in treating this condition.
  • - Researchers utilized network pharmacology and metabolomics to investigate the molecular mechanisms of TR in relieving AP, confirming their findings through various experimental models.
  • - Key results indicated that TR targets important inflammatory pathways and substances, specifically downregulating inflammatory factors and altering glycerophospholipid metabolism via the PI3K-Akt signaling pathway, demonstrating its potential as an anti-AP treatment.
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Objectives: The primary objective was to assess incidence and severity of acute laryngeal injury (ALgI) following intubation at time of tracheostomy using a proposed grading scale. The secondary objective was to evaluate what factors influence the rate of decannulation.

Methods: Single institution cohort study with review of prospectively maintained database including patients from October 2021 to October 2022 who underwent tracheostomy for prolonged intubation/critical illness.

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To evaluate the time of onset of dysphagia in a cohort of head and neck cancer patients treated with radiation or chemoradiation. Retrospective chart review of adult patients. 237 patients met inclusion criteria for the study.

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Article Synopsis
  • Occupational exposure to irritants leads to poor asthma control, but the long-term effects on irritant-induced occupational asthma (IIA) patients are not well understood.
  • A study evaluated 28 IIA patients years after diagnosis, measuring lung function, bronchial responsiveness, inflammation, and exercise capacity, revealing that many still had poor asthma control despite normal lung function.
  • While most participants showed a slight improvement in asthma control over time, reduced physical capacity was prevalent and linked to inadequate symptom management and heavy medication use.*
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Background: Dysphagia places a substantial burden on the critically ill, affecting 12%-84% of this cohort, and is independently associated with worse outcomes. Pharyngeal electrical stimulation (PES-treatment) is a novel dysphagia therapy with an emerging evidence base. This retrospective observational study describes our dysphagia service and reports the use of PES-treatment as a standard of care in recovering critically ill patients at a single-site tertiary UK hospital.

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Hereditary angioedema (HAE) in children and adolescents: New treatment options.

Allergol Select

October 2024

Hannover Medical School (MHH), Department of Dermatology, Allergology and Venereology, Interdisciplinary Allergy Center of the MHH, Treatment Center for Hereditary Angioedema of the MHH, Hannover, Germany.

Article Synopsis
  • Modern management of hereditary angioedema (HAE) emphasizes personalized treatment plans tailored to the needs of children and adolescents, as well as the severity of the disease.
  • New medications have improved quality of life for HAE patients, but not all are approved for children, leading to ongoing research into alternative treatments such as those targeting bradykinin effects.
  • Emerging options like oral medications, long-acting therapies, and potential gene therapy are being explored to better meet the care requirements for young patients with HAE type I and II.
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Article Synopsis
  • The 2023 Finnish guidelines for pediatric lower respiratory tract infections (LRTIs) were updated based on a systematic review of strong, moderate, and weak evidence from various studies.
  • Key recommendations include avoiding antitussives and beta-sympathomimetics for bronchitis, using oral corticosteroids for laryngitis, and prescribing a 5-day course of amoxicillin for community-acquired pneumonia.
  • The goal of the guidelines is to enhance evidence-based treatment for LRTIs in children, focusing on the correct use of antibiotics, inhaled therapies, corticosteroids, and appropriate testing.
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Article Synopsis
  • - The study analyzed the effectiveness of a 1.5% levofloxacin otic solution for treating acute otitis externa in patients with nonintact tympanic membranes who also had chronic and acute otitis media
  • - Researchers evaluated digital endoscopic images to assess inflammatory findings and track patient improvements, comparing results between those treated with levofloxacin and a placebo group
  • - Results showed that a significantly higher percentage of patients treated with levofloxacin experienced improvement in inflammatory symptoms (47.6%) and had high bacterial eradication rates (94.3%) compared to those on placebo.
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Laryngeal spindle cell carcinoma (SpCC) is a unique and very aggressive form of laryngeal cancer. This neoplasm, consisting of malignant epithelial and mesenchymal elements, presents major diagnostic challenges, and there is a lack of conventional therapeutic approaches due to its rarity. This report describes a case of a 53-year-old female who experienced persistent difficulty speaking and a dry cough after contracting coronavirus disease 2019 (COVID-19).

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Understanding and Treating Laryngeal Mask Airway-Induced Intraoperative Hiccups.

Cureus

September 2024

Department of Anesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

The laryngeal mask airway (LMA) has gained popularity as an airway management device in the perioperative setting due to its ease of use, reduced invasiveness compared to endotracheal intubation, and lower incidence of complications. However, hiccups, though relatively uncommon, can pose a significant challenge during the perioperative period when an LMA is in place. Abrupt movement because of hiccups can lead to delay in surgery as well as interfere with surgical instrumentation.

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