Molecular Characteristics of Sweet Syndrome: A Systematic Review.

Sweet syndrome (SS), originally described as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition, considered the prototype of neutrophilic dermatoses. It is characterised by the sudden onset of well-defined tender papules, plaques and nodules often accompanied by fever, neutrophilia and elevated markers of inflammation. Several variants have been described both clinically and histopathologically.

Weight and metabolic changes with long-acting cabotegravir and rilpivirine or bictegravir/emtricitabine/tenofovir alafenamide.

Background: Modest weight and lipid changes have been observed in cabotegravir plus rilpivirine long-acting (CAB+RPV LA) Phase 3/3b studies. The SOLAR study included standardized evaluations of weight and metabolic changes in people living with HIV switching to CAB+RPV LA dosed every 2 months (Q2M) vs. continuing bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF).

Decitabine-induced Sweet syndrome.

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition associated with the sudden onset of high-grade fever, painful rashes usually on the upper body, leukocytosis and neutrophilia. Approximately 21% of patients with Sweet syndrome have a concurrent malignancy, 80% of which are linked to haematological diseases, especially myelodysplastic syndrome and acute myeloid leukaemia. This is a case report of a woman in her 50s who was recently diagnosed with acute myeloid leukaemia and was started on decitabine 20 mg/m (40 mg).

Atypical Type 2 Lepra Reaction Masquerading as Recurrent Sweet Syndrome.

Erythema nodosum leprosum (ENL) is an immune complex-mediated response in Mycobacterium leprae infection, presenting with fever, arthralgias, and tender cutaneous lesions. It mimics Sweet syndrome (SS) clinically and histologically but requires distinct management. A 65-year-old man with recent travel presented with fever and edematous plaques.

Neurological Sweet's syndrome: a rare but treatable manifestation of an autoinflammatory disease.

Sweet's syndrome is an autoinflammatory disease characterised by systemic symptoms and a cutaneous neutrophilic dermatosis. Neurological involvement is rare but important to recognise. Patients may have headache, confusion, seizures, and focal neurological deficits; MR brain scanning may show widespread T2-hyperintense lesions, with a CSF pleocytosis.

Experience with Zone 2 Arch Replacement Followed by Thoracic Endovascular Aortic Repair.

Background:  Transverse open aortic arch replacement remains a complex operation. A simplified arch replacement into zone 2, with debranching the head vessels proximally, creates a suitable landing zone for future endovascular repair and is increasing in popularity as of late. Still, limited data exist to assess contemporary rates of morbidity and mortality.

Sweet syndrome: an update on clinical aspects, pathophysiology, and treatment.

Sweet syndrome is a neutrophilic dermatosis characterized by an autoinflammatory nature and a sterile neutrophilic infiltrate. It presents with tender, erythematous, edematous papules or plaques, often accompanied by fever. Aim of this review is to summarize the most meaningful aspects of Sweet syndrome, critically discussing old paradigms and novel findings.

Utilization of percutaneous closure devices for large bore arterial access in patients with genetic aortopathy does not result in increased rates of access site complications.

Objective: Percutaneous closure devices for arterial sheaths of sufficient caliber to deliver aortic endografts have a published success rate of 90% to 95%. Despite this, they are frequently avoided in patients with genetic aortopathy due to concern for high failure rates and increased complications in the setting of compromised tissue integrity. This study aims to compare rates of access site complications after large bore percutaneous access among patients with and without confirmed genetic aortopathy.

Mimickers of erysipelas and cellulitis: A narrative review.

A diffuse erythematous, edematous tender swelling with a distinct border and local rise in temperature suggest a morphological diagnosis of erysipelas-like eruption. While cellulitis and pseudocellulitis have an ill defined tender erythematous plaque. Erysipelas, and cellulitis are not a straightforward diagnosis as multiple cutaneous eruptions mimic erysipelas.

Sweet's Syndrome Unveiling a Primary Cervical Malignancy: A Case Report.

Sweet's syndrome (SS) is a relatively rare dermatological condition typically presenting with erythematous tender plaques, papules, nodules, or pustules accompanied by fever, asymmetric polyarthralgia, and other systemic features. Elevated inflammatory markers and white blood cell counts are also commonly seen in SS. Dense neutrophilic infiltration in the dermis is a cardinal feature of SS.

Sugar-sweetened beverages, low/no-calorie beverages, fruit juices intake and risks of metabolic syndrome in adults: The SWEET project.

Background And Aims: Metabolic syndrome (MetS) is an important determinant of cardiometabolic disease development, with excessive sugar intake as one of the key modifiable risk factors. However, evidence on the association between sugar-sweetened beverages (SSB), their replacement by low/no caloric beverages (LNCB), and MetS development is still limited.

Methods And Results: Data from participants' of Lifelines (n = 58 220), NQPlus (n = 1094) and Feel4Diabetes (n = 342) were prospectively analysed.

[Canine sterile neutrophilic dermatosis (Sweet-like syndrome): A description of 3 cases].

Three dogs were presented with a sudden onset of erythematous skin lesions, fever, and various extracutaneous signs, assigned to canine sterile neutrophilic dermatosis by clinical, laboratory, and histopathologic examination. This disease is very rare and comparable to Sweet syndrome in humans. According to the 4 forms of SS, the 1st and 3rd cases in this case report could be classified as classic/idiopathic SS.

Cryptococcoid Sweet syndrome: a case report.

Cryptococcoid Sweet syndrome (cSS) is a recently described clinical and histological variant of Sweet syndrome (SS). Its cutaneous presentation is similar to the classical form of SS but it includes atypical findings, such as capsular and yeast-like structures on microscopy that are reminiscent of species. However, in cSS, fungal staining and cultural examination are negative, whereas myeloperoxidase (MPO) staining on biopsy specimens is typically positive.