28 results match your criteria: "Actinic Purpura"
Ingenol mebutate-associated immune thrombocytopenic purpura.
JAAD Case Rep
April 2024
Dermatology Solutions, Grapevine, Texas.
Dermatoporosis in Upper Limbs Treated With Polymethylmethacrylate Microspheres Using the BioSculpt® Technique.
Cureus
August 2023
Plastic Surgery, University of California San Diego, San Diego, USA.
Article Synopsis
- Dermatoporosis is a condition characterized by fragile skin in older adults, showing symptoms like bruising and skin thinning, especially on the arms.
- An 80-year-old patient received treatment for dermatoporosis using a method called BioSculpt® with polymethylmethacrylate (PMMA).
- The effectiveness of the treatment was monitored through photographic and ultrasound assessments over a period of nine months.
Skin tears in older adult residents of long-term care facilities: prevalence and associated factors.
J Wound Care
June 2022
Medical-Surgical Nursing Department, University of São Paulo, São Paulo, Brazil.
Article Synopsis
- The study aimed to find out how common skin tears are among older adults in long-term care facilities in São Paulo, Brazil, and what factors might influence their occurrence.
- It involved 69 residents and found a skin tear prevalence of 11.6%, with significant associations to conditions like haematoma and actinic purpura, which greatly increased the likelihood of skin tears.
- This research is notable as it is the first of its kind in Brazil, providing important data on a topic that has not been previously explored in the country.
Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study.
Lasers Surg Med
September 2021
Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, RMSB 2023A, Miami, Florida, 33136.
Article Synopsis
- Senile purpura is a condition in older adults characterized by bruises, particularly on exposed areas like forearms and hands, and this study aimed to evaluate a new treatment method using intense pulsed light (IPL) to improve its appearance.
- The study involved two groups: five older adults (over 65) with severe bruising and five younger adults (under 35) without any bruises, with treatments conducted over four weeks on one arm of each participant.
- Results showed that IPL significantly reduced both the number and size of ecchymoses after treatment in older adults, indicating the procedure's potential effectiveness and safety for treating senile purpura.
Clinical purpura and elastosis and their correlation with skin tears in an aged population.
Arch Dermatol Res
April 2019
School of Public Health, Curtin University, Kent St, Bentley, WA, 6102, Australia.
Article Synopsis
- A cohort study was conducted on individuals over 65 to create a risk prediction model for skin tears, identifying key predictors such as male gender, history of skin tears, falls, purpura, and elastosis.
- Among 173 participants, 41% developed skin tears, with a significant number showing purpura and elastosis at baseline.
- The study found that certain individual characteristics and skin properties, influenced by aging and lifestyle, were linked to the increased risk of these skin manifestations and tears.
Laser Therapy for Actinic Purpura.
Dermatol Surg
November 2019
San Antonio Uniformed Services Health Education Consortium, Department of Dermatology San Antonio, Texas San Antonio Military Health System, Department of Dermatology San Antonio, Texas UC San Diego Health, Department of Dermatology San Diego, California Massachusetts General Hospital, Department of Dermatology Boston, Massachusetts.
Treatment of Actinic Purpura.
J Clin Aesthet Dermatol
June 2017
Dermatology PC, West Des Moines, Iowa.
Article Synopsis
- * The condition is common among both men and women and becomes more frequent with age.
- * A new treatment product featuring ingredients like retinol, α-hydroxy acids, arnica oil, ceramides, niacinamide, and phytonadione aims to enhance circulation, thicken the skin, and repair the skin barrier to address actinic purpura.
Mechanisms of skin aging induced by EGFR inhibitors.
Support Care Cancer
October 2016
Department of Dermatology, Medical Faculty, University of Düsseldorf, Moorenstrasse 5, D-40225, Duesseldorf, Germany.
Article Synopsis
- The study investigates how EGFR inhibitors (EGFRIs) affect skin aging by examining patients receiving long-term treatment and analyzing their skin changes.
- It finds that patients show signs of aging like dry skin, thinning, and wrinkles after prolonged use of EGFRIs, which correlates with changes at the cellular level in keratinocytes.
- The research concludes that the inhibition of EGFR leads to molecular changes, including altered gene expression and cell cycle behavior, contributing to the skin aging observed in these patients.
Article Synopsis
- Cutaneous dyschromia refers to changes in skin pigmentation caused by various medical issues or medications.
- The case discussed involves minocycline, an antibiotic, which caused skin discoloration mistakenly diagnosed as chronic actinic purpura, a skin condition related to sun damage.
- The report highlights the importance of accurate diagnosis in dermatological conditions to avoid misattributing symptoms to the wrong cause.
Human T-lymphotropic virus 1 (HTLV-1)-associated lichenoid dermatitis induced by CD8+ T cells in HTLV-1 carrier, HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia/lymphoma.
J Dermatol
October 2015
Department of Dermatology and Wound Healing, School of Medicine, Cardiff University, Cardiff, UK.
Article Synopsis
- Human T-lymphotropic virus type 1 (HTLV-1) can lead to conditions like adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), often presenting with various skin lesions.
- A study reviewed 50 patients from 2002-2012 with ATLL, HAM/TSP, and HTLV-1 carriers who had skin issues, identifying reactive skin eruptions characterized by lichenoid tissue reactions and a predominance of CD8+ T cells.
- The researchers introduced the term HTLV-1-associated lichenoid dermatitis (HALD) to describe these skin conditions, suggesting they may be linked
Chemotherapy-induced inflammation of actinic keratosis can present in patients with subclinical actinic keratoses that become erythematous and pruritic within weeks of initiating systemic chemotherapy. The reaction is limited to sun-exposed areas and, classically, histologic findings of parakeratosis and epidermal necrosis with keratinocyte nuclear pleomorphism are present. Exuberant reactions with extensive epidermal necrosis may lead to subepidermal vesiculation.
View Article and Find Full Text PDF[A woman with red-purple blotches].
Ned Tijdschr Geneeskd
July 2014
Waterland Ziekenhuis, afd. Dermatologie, Purmerend.
Article Synopsis
- A 56-year-old woman showed up with painless, red-purple blotches on her forearms that appeared suddenly.
- Lab tests came back normal, indicating no serious underlying issues.
- A tissue analysis confirmed she had non-inflammatory actinic purpura, common in older adults due to weakened collagen in the skin.
Origin Use of CD4, CD8, and CD1a Immunostains in Distinguishing Mycosis Fungoides from its Inflammatory Mimics: A Pilot Study.
Indian J Dermatol
November 2012
Department of Pathology, St. John's Medical College, Bangalore, India.
Unlabelled: Patch-stage/early mycosis fungoides (MF) is difficult to differentiate from benign dermatoses, despite several robust histologic criteria. Most studies include advanced lesions and data about early disease is limited.
Objectives: (1) To compare the CD4:CD8 ratio in patch-stage MF versus inflammatory mimics.
Reversing precancerous actinic damage by mixing wavelengths (1064 nm, 532 nm).
J Cosmet Laser Ther
June 2011
Article Synopsis
- * Ten patients with actinic keratosis or carcinoma in situ received just one session of this mixed laser treatment, with minimal pain and irritation, leading to quick and effective results.
- * The findings suggest this laser method is a fast, painless, and efficient alternative for treating these lesions compared to traditional methods, offering excellent cosmetic results without downtime.
Dermatologic lasers in the treatment of aging skin.
Acta Dermatovenerol Croat
January 2011
University Hospital Center Zagreb , Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Šalata 4, Zagreb, Croatia.
Article Synopsis
- Skin aging is divided into intrinsic aging, which is natural and unavoidable, and photoaging, which results from sun exposure and is not universal.
- Key signs of aging skin include dryness, wrinkles, sagging, and issues like benign growths, while photoaging adds irregular pigmentation and other skin texture problems.
- Modern antiaging treatments include lasers, fillers, and chemical peels, with a trend towards less invasive nonablative procedures due to quicker recovery times, despite offering only mild improvements.
Bowen's disease concealed by purpura.
J Dermatol
January 2007
Department of Dermatology, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea.
Article Synopsis
- Bowen's disease (BD) is a type of squamous cell carcinoma in situ that appears as a red, scaly plaque with an irregular edge.
- BD is often misidentified as several skin conditions, including basal cell carcinoma, dermatitis, psoriasis, and even melanoma.
- The text presents two cases where BD looked like purpura on elderly patients' scalps, leading to a wrong initial suspicion of angiosarcoma.
Laser-mediated photodynamic therapy of actinic cheilitis.
J Drugs Dermatol
January 2005
Yale University School of Medicine, Department of Dermatology, New Haven, CT, USA.
Article Synopsis
- Actinic cheilitis (AC) is a precancerous condition needing effective treatment; this study evaluates the safety and efficacy of long-pulsed dye laser (LP PDL) combined with photodynamic therapy (PDT) using 5-aminolevulinic acid for AC management.
- In a pilot study with 21 patients, those treated with ALA-PDL showed significant improvement, achieving complete clearance in 68% of cases after an average of 1.8 treatments, while control patients received only LP PDL.
- The treatment was generally well-tolerated, with minimal pain and erythema, and side effects like impetiginization resolved,
Laser-mediated photodynamic therapy of actinic keratoses.
Arch Dermatol
October 2003
Laser & Skin Surgery Center of New York, New York 10016, USA.
Article Synopsis
- The study evaluated the safety and effectiveness of the long-pulsed pulsed dye laser (LP PDL) combined with photodynamic therapy (PDT) for treating actinic keratoses (AKs) in 41 volunteer patients aged 35-91.
- Results showed high lesion clearance rates, especially in head lesions, where around 99% were cleared by 10 days, with significant, though lower, percentages maintained for up to 8 months.
- The procedure was generally safe, with minimal pain and side effects, and no significant difference in outcomes between different incubation times of the topical treatment.
Modulating diseased skin with tissue engineering: actinic purpura treated with Apligraf.
Dermatol Surg
December 2002
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA.
Article Synopsis
- * The study evaluated Apligraf, a tissue-engineered skin product, as a potential treatment for AP by replacing damaged skin in an elderly patient.
- * Results showed that the Apligraf treatment led to rapid healing and reduced skin tearing, suggesting it may provide a more durable solution for managing AP in certain cases.
[Cutaneous complications following liver transplantation: epidemiologic and clinical study in 86 patients].
Ann Dermatol Venereol
October 2002
Service de Dermatologie, CHU Saint-Jacques, Besançon.
Article Synopsis
- Organ transplant patients often face skin issues due to immunosuppressive treatments, with more research on kidney transplants than liver transplants.
- A study at a university hospital examined 86 liver transplant patients, focusing on skin side effects, infections, and tumor development from January 1997 to May 1998.
- Results showed a high prevalence of skin issues like hypertrichosis and infections, with 17.4% developing actinic keratoses and some skin cancers; findings suggest similar rates of skin problems between liver and kidney transplant patients, but differing frequencies of specific skin cancers.
New and emerging treatments for photoaging.
Dermatol Clin
January 2000
Center for Dermatologic Surgery, Cooper Health System, Marlton, New Jersey, USA.
Article Synopsis
- It's common for healthcare providers to focus more on treating the effects of photoaging, skin cancers, and actinic keratoses rather than on preventive measures.
- For children, the focus should be on sun protection and educating about sunscreen use as the primary way to prevent skin issues.
- For young adults and older patients with existing skin damage, treatments like topical applications and resurfacing can help improve their skin condition and overall daily functioning.
Multivariate analysis of cutaneous markers of aging in chronic hemodialyzed patients.
Int J Dermatol
August 1995
Department of Dermatology, University of Granada Hospital, Spain.
Article Synopsis
- Hemodialysis patients exhibit a high prevalence of cutaneous aging lesions, with various skin conditions such as senile lentigo and actinic keratoses observed.
- A study of 114 patients revealed that facial wrinkles and decreased skin hydration significantly correlated with the duration of hemodialysis treatment.
- The findings indicate that prolonged exposure to hemodialysis may accelerate the process of skin aging in these individuals.
The clinical identification and quantification of photodamage.
Br J Dermatol
September 1992
Department of Dermatology, University of Michigan Medical Center, Ann Arbor 48109-0314.
Article Synopsis
- The text differentiates between intrinsic and extrinsic ageing, highlighting that extrinsic ageing is influenced by external factors and is identifiable through specific clinical signs.
- Common clinical indicators of extrinsic ageing include coarse wrinkles, sun spots, and various skin conditions, which are layered on top of changes seen with intrinsic ageing, like fine wrinkles.
- There is growing interest in addressing extrinsic ageing, particularly due to the effectiveness of topical tretinoin, leading to the creation of a standardized photographic grading system to better assess these skin changes.