Spontaneous twin anemia polycythemia sequence: diagnosis, management, and outcome in an international cohort of 249 cases.

Background: Twin anemia polycythemia sequence is a chronic form of unbalanced fetofetal transfusion through minuscule placental anastomoses in monochorionic twins, leading to anemia in the donor and polycythemia in the recipient. Owing to the low incidence of twin anemia polycythemia sequence, data on diagnosis, management, and outcome are limited.

Objective: This study aimed to investigate the diagnosis, management, and outcome in a large international cohort of spontaneous twin anemia polycythemia sequence.

[The morphological and molecular biological signs of impaired endometrial receptivity in infertility in women suffering from external genital endometriosis].

Objective: To study endometrial receptivity in infertile women with external genital endometriosis (EGE).

Subjects And Methods: Clinical, morphological, immunohistochemical, and molecular genetic examinations of endometrial aspiration pipelle biopsy specimens obtained on days 22-24 of the menstrual cycle from 94 infertile women with endometriosis: 50 women with Stage I-II EGE and 44 women with ovarian endometrioid cysts (OEC). A control group consisted of 54 women with tubal peritoneal factor of infertility (TPFI) and a successful attempt at IVF.

[Pathological estimation of the time of fetal death].

The paper analyzes the data available in the literature on the possibilities of determining the time of fetal death during an autopsy study. It presents gross changes in the appearance and internal organs of the fetus, as well as histological changes in the organs and placenta, which develop during maceration. The microscopic characteristics of the development of lung and kidney tissues are given in relation to the gestational age of the fetus.

[The reference intervals of main parameters of urine for analyzers SYSMEX UF 1000I/500I in dynamics of uncomplicated pregnancy.].

The analyzer Sysmex UF1000i/500i were used to measure 8 parameters of urine of pregnant women; the upper reference values were formed. The women (n=158) with uncomplicated course of pregnancy were examined. No calculation of reference intervals was applied to leukocytes, erythrocytes, pavement and transitional/renal epithelium, cylinders (pathological ones included) due to their correspondence to similar values for non-pregnant women.

[Morphological substrate and pathogenetic mechanisms of pelvic pain syndrome in endometriosis. Part II. Peripheral nerve tissue remodeling in the foci of endometriosis].

Unlabelled: Endometriosis (EM) is morphologically characterized by the development of extrauterine endometrioid heterotopies, the major clinical symptoms of which is chronic pelvic pain, which is a serious problem not only in modern gynecology, but also in public health as a whole.

Aim: to investigate neurogenic markers in the foci of EM of various sites and histological structure in women with and without pain syndrome.

Material And Methods: The investigation was performed using the operative material (resected segments of the intestine, bladder, rectovaginal septum, and small pelvic peritoneum) obtained from 52 women with an intraoperative and morphologically verified diagnosis of EM and (Group 1) and without (Group 2) pain syndrome.

[Histological hanges in the placenta and vascularization of its villi in early- and late-onset preeclampsia].

Aim: to make a comparative histological study of the placenta and a morphometric analysis of its terminal villi in early- and late-onset preeclampsia.

Material And Methods: Placentae from patients whose pregnancy had been complicated by the development of early- (n=26) or late-onset (n=84) preeclampsia were examined. A control group comprised placentae from 28 patients with physiological pregnancy and no extragenital diseases.

[The mass-spectrometry as a new word in clinical microbiology].

In the end of XX century real revolution occurred in field of methods, which can be applied for identification of agents of infections including bacteria. Alongside with cultural diagnostic entered an arsenal of molecular genetic methods and proteomic analysis based on application of physical technologies including matrix activated laser desorption/ionization time-of-flight mass spectrometry - MALDI-ToF MS as well. The international experience of application of MALDI-ToF MS as species identification of microorganisms isolated from clinical samples substantiates high importance of method.

[Vascularization of hepatoceliular carcinoma].

The paper gives the data available in the literature on vascularization of hepatocellular carcinoma (HCC). Sinusoidal capillarization and unpaired arteries are shown to play an important role in the development and progression of HCC. The density of microvessels detected by immunohistochemical techniques is a morphological indicator of the degree of angiogenic processes.