15 results match your criteria: "Academic Teaching Hospital of the Ruhr University Bochum[Affiliation]"

Article Synopsis
  • Advancements in molecular engineering have led to the development of CAR T-cell therapy, showing potential for treating various neurological disorders, including brain tumors and autoimmune conditions.
  • Although initial human trials for treating glioblastoma have had limited success, animal studies show promise for other conditions like multiple sclerosis and neuromyelitis optica spectrum disorders.
  • Innovative strategies using modified CAR T cells targeting autoreactive B cells are showing potential for treating autoimmune encephalitis, suggesting a hopeful future for CAR T-cell applications in neurology.
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Objectives: To standardize optic nerve sheath diameter (ONSD) point-of-care ultrasonography (POCUS) and improve its research and clinical utility by developing the ONSD POCUS Quality Criteria Checklist (ONSD POCUS QCC).

Design: Three rounds of modified Delphi consensus process and three rounds of asynchronous discussions.

Setting: Online surveys and anonymous asynchronous discussion.

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Background: The treatment of ischemic stroke (IS) has changed considerably in recent years. Particularly the advent of mechanical thrombectomy (MTE) has revolutionized the available treatment options. Most patients in developed countries have access to intravenous thrombolysis (IVT).

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The γ-aminobutyric acid (GABA) is the main inhibitory transmitter in the central nervous system and GABA receptors mediate the inhibitory synaptic transmission. GABA binding to neuronal GABA R leads to a rapid hyperpolarization and a higher excitation threshold due to an increase in membrane Cl permeability. The synaptic GABA R is mostly composed of two α(1-3), two β, and one γ subunit with the most abundant configuration α1β2γ2.

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Introduction: Epiploic appendagitis is a rare cause of focal abdominal pain which, depending on its localisation, can mimic a variety of abdominal diseases. We describe a patient with an inflamed necrotic appendix epiploicum with immediate contact to a non-inflamed appendix vermiformis mimicking acute appendicitis. Considering the rare localization, this is the first report of this kind in the literature.

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Introduction: In-flight medical and surgical emergencies (IMEs) onboard commercial aircrafts occur quite commonly. However, little epidemiological research exists concerning these incidents.

Methods: Thirty-two European airlines were asked to provide anonymous data on medical flight reports of IMEs for the years 2002 to 2007.

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Cutaneous lesions of the external ear.

Head Face Med

February 2008

Department of General and Visceral Surgery, Augusta Kranken Anstalt, Academic Teaching Hospital of the Ruhr-University Bochum, Germany.

Skin diseases on the external aspect of the ear are seen in a variety of medical disciplines. Dermatologists, othorhinolaryngologists, general practitioners, general and plastic surgeons are regularly consulted regarding cutaneous lesions on the ear. This article will focus on those diseases wherefore surgery or laser therapy is considered as a possible treatment option or which are potentially subject to surgical evaluation.

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Skin cancer on the nose is commonly treated with surgical excision resulting in defects that require closure. The surgeon is faced with many reconstructive options. The paramedian forehead flap is one commonly used technique.

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Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C-cells which can secrete adrenocorticotropic hormone (ACTH) and/or corticotropin-releasing factor (CRF) in abnormally high concentrations, potentially causing paraneoplastic Cushing's Syndrome (CS). We report on a 42-year-old male patient with a ten year history of metastatic medullary thyroid carcinoma suffering from paraneoplastic Cushing's Syndrome caused by ectopic hypersecretion of ACTH and a simultaneous Cortisol producing adrenal metastasis.

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Background: Epiploic appendagitis (EA) is a rare cause of focal abdominal pain in otherwise healthy patients with mild or absent secondary signs of abdominal pathology. It can mimick diverticulitis or appendicitis on clinical exam. The diagnosis of EA is very infrequent, due in part to low or absent awareness among general surgeons.

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Keloids are defined as dermal fibrotic lesions which are considered an aberration of the wound healing process. Their etiology and pathogenesis are poorly understood. Different treatment modalities are described in the literature depending on the morphology and size of the keloid.

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Synopsis of otoplasty.

Facial Plast Surg

November 2004

Department of Otorhinolaryngology, Head and Neck Surgery, Prosper Hospital, Academic Teaching Hospital of the Ruhr University Bochum, 45659 Recklinghausen, Germany.

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Correction of the lobule.

Facial Plast Surg

November 2004

Department of Otorhinolaryngology, Head and Neck Surgery, Prosper Hospital, Academic Teaching Hospital of the Ruhr University Bochum, 45659 Recklinghausen, Germany.

Many techniques have been described for the correction of protruding ears. Most of them concentrate on correcting the form and position of auricular cartilage. The lobule is a soft tissue structure.

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The modified converse technique in combination with cavum rotation.

Facial Plast Surg

November 2004

Department of Otorhinolaryngology, Head and Neck Surgery, Prosper Hospital, Academic Teaching Hospital of the Ruhr University Bochum, 45659 Recklinghausen, Germany.

We report our experiences in 210 patients with protruding ears who underwent a surgical correction of their deformity using a modified "Converse technique." The technique combines a posterior incomplete cartilage incision with permanent cartilage sutures and a cavum rotation if necessary. The described technique provides a good anterior width and normal relief, with shaped anthelix and crus superior, can be achieved.

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