4 results match your criteria: "Academic Hospital of RWTH Aachen[Affiliation]"
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
Plasma level of Osteopontin does not respond to total replacement Surgery in patients with severe Primary knee/Hip Osteoarthritis.
J Orthop
September 2017
Department of Orthopaedic Surgery, Aachen University Hospital, Aachen, Germany.
Article Synopsis
- The study aimed to assess how Osteopontin levels change in patients with knee or hip Osteoarthritis after undergoing replacement surgery.
- Plasma samples were collected from 30 patients (16 with knee and 14 with hip Osteoarthritis) before and three months after surgery to analyze the results.
- The findings indicated that Osteopontin levels remained unchanged, suggesting that these levels do not respond to replacement treatment.
Osteopontin as a biochemical marker and severity indicator for idiopathic hip osteoarthritis.
Hip Int
July 2016
Department of Orthopaedic Surgery, Aachen University Hospital, Aachen - Germany.
Article Synopsis
- A study was conducted to evaluate the connection between plasma osteopontin (OPN) levels and the severity of hip osteoarthritis (OA) in 21 patients experiencing severe idiopathic hip OA.
- The results showed that 66.66% of patients had K-L grade 3 changes and 33.33% had grade 4 changes, with OPN levels significantly higher in OA patients compared to normal values.
- Higher OPN levels correlated with increased severity, indicating that OPN could serve as a potential biomarker for assessing the progression of idiopathic hip OA.
Two-Step Reconstruction of Non-Marginal Auricular Defects.
J Oral Maxillofac Surg
July 2016
Consultant, Department of Oral and Maxillofacial Surgery, Hospital Detmold, Academic Hospital of the University of Hannover, Detmold; Medical Faculty University RWTH Aachen, Aachen, Germany.
Article Synopsis
- * The method was used on 13 patients who experienced partial to complete loss of the auricular concha, using local anesthesia in an outpatient setting.
- * Results showed excellent aesthetic outcomes with minimal complications, including no flap necrosis, and effective donor site closure, highlighting the technique's efficiency and effectiveness.