328 results match your criteria: "Abubakar Tafawa Balewa University[Affiliation]"

Background: Kidney transplantation is the best mode of kidney replacement therapy. However, the shortage of organ donations has been a major challenge globally. Relatives of patients with end-stage kidney disease (ESKD) are potential kidney donors.

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The COVID-19 pandemic challenged health systems globally. Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for detecting the presence of SARS-CoV-2 in clinical samples. Rapid diagnostic test (RDT) kits for COVID-19 have been widely used in Nigeria.

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Article Synopsis
  • Extra-pulmonary tuberculosis (EPTB) is a significant health issue contributing to TB's burden, particularly in developing nations, but data on its prevalence is limited.
  • A study conducted at Abubakar Tafawa Balewa University Teaching Hospital in Nigeria analyzed records of TB patients from 2017 to 2021, revealing a five-year prevalence of 30.8% for EPTB, with spinal TB being the most common type.
  • The findings highlight the ongoing high prevalence of EPTB and emphasize the importance of continuous screening efforts in order to tackle the TB epidemic, especially in low-resource settings.
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Background: Due to the high premium placed on childbearing, infertility puts a lot of stress on the family which may result in aggressive and irrational behaviour if not properly managed. Domestic violence (DV) against infertile women is a public health issue but under-reported especially in northern Nigeria.

Objectives: This study sought to identify the prevalence, pattern, and response to DV.

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Article Synopsis
  • The study compares fascia iliaca compartment block (FICB) versus intravenous analgesics for managing severe pain in patients with femoral fractures.
  • Conducted with 50 patients, the FICB group received a local anesthetic while the control group received placebo along with intravenous paracetamol and tramadol.
  • Results showed that FICB provided significantly better pain relief and patient satisfaction compared to the intravenous analgesic treatment.
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Lymphatic filariasis is a neglected tropical disease that affects the lymphatic system of humans. The major etiologic agent is a nematode called Wuchereria bancrofti, but Brugia malayi and Brugia timoriare sometimes encountered as causative agents. Mosquitoes are the vectors while humans the definitive hosts respectively.

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Microplastics (MPs) and their co-pollutants pose significant threats to soil and marine environments, necessitating understanding of their colonization processes to combat the plastic pandemic and protect ecosystems. MPs can act as invisible carriers, concentrating and transporting pollutants, leading to a more widespread and potentially toxic impact than the presence of either MPs or the pollutants alone. Analyzing the sorption and desorption dynamics of MPs is crucial for understanding pollutants amplification and predicting the fate and transport of pollutants in soil and marine environments.

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  • Nigeria's neurosurgery field struggles with a dire lack of neurosurgeons, high migration rates of medical professionals, and limited access to care due to urban-centric centers and financial barriers.
  • Key issues include inadequate manpower, poor emergency services, lack of imaging and surgical equipment, and ineffective policies, resulting in poor management of neurotrauma cases and limited subspecialization opportunities in training.
  • To improve the situation, it's essential to enhance infrastructure, expand training capacity especially in rural areas, implement unified residency matching, address gender disparities, and promote international collaboration for research and funding.*
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Background: Interprofessional collaboration in healthcare is important to optimise healthcare delivery. However, relatively few studies have been conducted on the topic in Nigeria, especially in the North.

Objective: The objective of this study was to determine the levels of interprofessional collaboration, enablers and barriers amongst healthcare workers.

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  • The study assessed cardiovascular risk awareness and exercise practices among Nigerians with diabetes, finding that many participants had low knowledge of cardiovascular risk factors and exercise guidelines.
  • Out of 426 participants, only 43% engaged in adequate exercise, which was linked to factors like younger age, male gender, and higher education levels.
  • Those who exercised adequately showed lower systolic blood pressure and serum urea levels, but no significant differences were found in other metabolic outcomes like body mass index or blood glucose levels.
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There is an interplay between oncology and mental health, resulting in a high prevalence of mental disorders among cancer patients. Out of the several interventions developed to target cancer specifics, collaborative care is indicated due to its efficacy. The perspective delves into the efficacy of collaborative care models, spotlighting a culturally informed strategy designed to harmonize mental and physical health interventions to bolster the overall wellbeing and resilience of individuals battling cancer.

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Background: Despite the huge burden of sickle cell disease (SCD) among Nigerian children, the burden and outcome of respiratory illnesses remain undocumented. Thus, we aimed to describe the spectrum and outcome of respiratory illnesses among SCD childrenand adolescentadmissions in ten Nigerian tertiary hospitals.

Method: A retrospective review of the SCD admission records of children and adolescents with a confirmed diagnosis of respiratory illnesses from 2012 to 2021 in ten tertiary health facilities across five geopolitical zones in Nigeria was conducted.

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Background: Like many low- and-middle-income countries in Africa, documented assessment of the neurosurgical workforce, equipment, infrastructure, and scope of service delivery in Nigeria is lacking. This study aimed to assess the capacity for the delivery of neurosurgical services in Nigeria.

Methods: An 83-question survey was disseminated to neurosurgeons and residents in Nigeria.

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Objective: There has been a modest but progressive increase in the neurosurgical workforce, training, and service delivery in Nigeria in the last 2 decades. However, these resources are unevenly distributed. This study aimed to quantitatively assess the availability and distribution of neurosurgical resources in Nigeria while projecting the needed workforce capacity up to 2050.

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Article Synopsis
  • - Insect monitoring is essential for evaluating biodiversity and shaping conservation efforts, particularly in developing regions known as the Global South, which face significant research disparities compared to the Global North.
  • - The study identifies various socio-economic and infrastructural challenges, such as limited funding, collaboration issues, and negative impacts from environmental changes, which hinder effective insect research and monitoring in these areas.
  • - Proposed solutions include enhancing community engagement, improving language inclusivity, leveraging social media for communication, and fostering collaborations with Global North researchers in advanced fields to improve insect monitoring and support biodiversity conservation.
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The proliferation of the Internet of Things (IoT) devices has led to a surge in Internet traffic characterized by variabilities in Quality of Service (QoS) demands. Managing these devices and traffic effectively proves challenging, particularly within conventional IoT network architectures lacking centralized management. However, the advent of Software-Defined Networking (SDN) presents intriguing opportunities for network management, capable of addressing challenges in traditional IoT architectures.

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Background: Traditional medicine is a constellation of practices, approaches, knowledge, and beliefs, which encompass material-based medicines, spiritual therapies, and manual techniques applied individually or combined.

Aim: This study seeks to determine the cost and visual status of traditional eye treatments users among new patients at a health facility.

Materials And Methods: This is part of the study titled "Traditional eye practices: A facility-based study in North Central Nigeria.

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Comprehensive review of the repositioning of non-oncologic drugs for cancer immunotherapy.

Med Oncol

April 2024

Center for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600077, India.

Article Synopsis
  • Drug repositioning, or repurposing, is a growing strategy to find new uses for existing approved or failed drugs, particularly for treating diseases like cancer.
  • This review focuses on non-oncologic drugs and their potential roles in chemotherapy, utilizing in silico modeling and literature reviews to identify suitable compounds.
  • It also explores the mechanisms of action of these repurposed drugs, discusses possible targets and key pathways, and addresses challenges in applying drug repositioning for cancer immunotherapy.
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Background: Malaria remains a burden globally, with the African region accounting for 94% of the overall disease burden and deaths in 2019. It is the major cause of morbidity and mortality among children in Nigeria. Though different environmental factors have been assessed to influence the distribution and transmission of malaria vectors, there is a shortage of information on how they may influence malaria transmission among under-fives in Nigeria.

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The identification of mitotic figures is essential for the diagnosis, grading, and classification of various different tumors. Despite its importance, there is a paucity of literature reporting the consistency in interpreting mitotic figures among pathologists. This study leverages publicly accessible datasets and social media to recruit an international group of pathologists to score an image database of more than 1000 mitotic figures collectively.

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Objective: To estimate the prevalence of obstructed labour, associated risk factors and outcomes across a network of referral hospitals in Nigeria.

Design: Retrospective observational study.

Setting: A total of 54 referral-level hospitals across the six geopolitical regions of Nigeria.

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Purpose: The anterolateral (AL) and anteromedial (AM) surfaces of the humerus are typically used for plate placement during plate osteosynthesis of midshaft humeral fractures via the anterolateral approach. The purpose of this study was to determine if a significant difference exists in the rates of iatrogenic radial nerve palsy (IRNP) following either AL or AM humeral fracture plating. The research question is stated as follows: is anteromedial plating of humeral fractures associated with lower rates of IRNP when compared with anterolateral plating?

Methods: This multicenter prospective randomized study was undertaken following ethical review and approval with eligible patients who had midshaft humeral fractures or nonunions randomized into 2 groups, viz AL plate osteosynthesis group and AM plate osteosynthesis group.

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Establishment of Maternal and Perinatal Database for Quality, Equity and Dignity programme: Processes, challenges, lessons and prospects.

BJOG

August 2024

UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

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