2,325 results match your criteria: "Abortion Incomplete"

Causal Relationship Between Circulating Immune Cells and Recurrent Spontaneous Abortion: A Bidirectional Mendelian Randomization Study.

Am J Reprod Immunol

June 2024

Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai Medical College, Shanghai, China.

Article Synopsis
  • Recurrent spontaneous abortion (RSA) is a complex pregnancy issue influenced by various factors, especially immunologic ones, and this study investigates the role of immune cells in RSA.
  • The researchers conducted a Mendelian randomization study analyzing 731 immune cell types to determine their causal effects on spontaneous abortions and recurrent miscarriages, while also addressing potential biases.
  • The study found eight immune cell markers significantly linked to spontaneous abortions and identified two markers related to recurrent miscarriage, demonstrating a clear immune component in these reproductive challenges without signs of bias or alternative explanations.
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The yield of a comprehensive investigation protocol for the diagnosis of true idiopathic ventricular fibrillation in a real-life clinical setting.

Sci Rep

June 2024

Department of Internal Medicine and Cardiology, University Hospital Brno and Faculty of Medicine, Masaryk University, Jihlavska 20, 625 00, Brno, Czech Republic.

Article Synopsis
  • * Researchers analyzed data from 514 ACA patients, identifying 46 who met specific criteria for an advanced diagnostic work-up, which included various imaging and testing methods.
  • * Results showed that 37% of patients had a specific disease discovered, while true idiopathic VF was confirmed in only 15.2%, suggesting that even partial diagnostic efforts can lead to meaningful findings for targeted treatment.
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  • Recurrent miscarriage (RM) is a challenging pregnancy issue, and researchers suggest that dysfunctional human trophoblast stem cells (hTSCs) might be involved, although the exact causes are still unclear.
  • This study identifies Forkhead box M1 (FOXM1) as a potential key factor linked to RM, highlighting its role as a transcription factor necessary for hTSC function, though its specific effects in this context are not fully understood.
  • The research shows that FOXM1 is more highly expressed in certain types of trophoblasts associated with growth and that its lower levels are correlated with RM, indicating that FOXM1 may influence important processes like cell proliferation and the cell cycle via transcriptional regulation.
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Article Synopsis
  • In 2006, a Colombian Constitutional Court ruling partially decriminalized abortion, but many women still chose to self-manage their abortions using medications acquired informally due to barriers in accessing formal healthcare services.
  • A 2018 study involving interviews with 47 women revealed a lack of trust in the healthcare system and misinformation about the abortion law as key reasons for this preference for informal methods.
  • Despite a progressive abortion law adopted in 2022, understanding the motivations behind self-managed abortions could help improve knowledge and access to legal abortion services in the future.
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Article Synopsis
  • * It found women who are unmarried, have a history of abortion or stillbirth, and those living in poor housing are at higher risk of having babies with NTDs.
  • * Conversely, early supplementation with folic acid or multivitamins significantly reduced the risk of NTDs by 43%.
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Retrospective evaluation of gestational trophoblastic disease - experience with ultrasounds.

Eur Rev Med Pharmacol Sci

May 2024

Obstetric and Gynecology Department, Sağlık Bilimleri University, Konya City Hospital, Konya, Turkey.

Objective: Our study aims to determine the frequency and types of GTD (Gestational Trophoblastic Disease) in our clinic, to evaluate its relationship with clinical parameters, and the consistency of clinical prediagnosis and pathological definitive diagnosis.

Patients And Methods: In the present study, hospital records of 120 patients with gestational trophoblastic disease between January 2019 and August 2022 were obtained and evaluated retrospectively. Demographic, hematological, biochemical, and clinical data were collected in detail, and the data were analyzed statistically.

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Background: Morgagni hernia (MH) is a form of congenital diaphragmatic hernia (CDH) characterized by an incomplete formation of diaphragm, resulting in the protrusion of abdominal organs into the thoracic cavity. The estimated incidence of CDH is between 1 in 2000 and 1 in 5000 live births, although the true incidence is unknown. MH typically presents in childhood and can be diagnosed either prenatally or postnatally.

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The presentation of a bicornuate uterus may include miscarriages and menstrual abnormalities. The diagnosis could be in an incident of caesarean delivery, miscarriage or hysteroscopy. The possibility of misdiagnosis to an ectopic pregnancy is real.

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Equine herpesvirus type 1 (EHV-1) is a contagious respiratory pathogen that infects the mucosa of the upper respiratory tract (URT). Mucosal immune responses at the URT provide the first line of defense against EHV-1 and are crucial for orchestrating immunity. To define host-pathogen interactions, we characterized B-cell responses, antibody isotype functions, and EHV-1 replication of susceptible (non-immune) and clinically protected (immune) horses after experimental EHV-1 infection.

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The Hyphomicrobiales bacterial order (previously Rhizobiales) exhibits a wide range of lifestyle characteristics, including free-living, plant-association, nitrogen-fixing, and association with animals (Bartonella and Brucella). This study explores the diversity and evolutionary strategies of bacteriophages within the Hyphomicrobiales order, comparing animal-associated (AAB) with non-animal-associated bacteria (NAAB). We curated 560 high-quality complete genomes of 58 genera from this order and used the PHASTER server for prophage annotation and classification.

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Objective: To investigate the protective effects against abnormal uterine bleeding (AUB) and possible mechanisms of Xue Ping tablets (XPT) using a rat model.

Methods: A total of 58 unmated female and 25 male SPF SD rats aged 8-9 weeks were selected. Eight unmated female rats were selected as the blank control group according to the complete random method.

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Objectives: To evaluate the implementation of mifepristone and misoprostol for medical management of early pregnancy loss (EPL) in emergency departments (EDs) by comparing efficacy, complication, and follow-up rates for patients treated in EDs to the Complex Family Planning (CFP) outpatient office.

Study Design: In COVID-19's first wave, we expanded medical management of EPL to our EDs. This retrospective study evaluated 72 patients receiving mifepristone and misoprostol for EPL from April 1, 2020 to March 31, 2021, comparing treatment success, safety outcomes, and follow-up rates by location.

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Purpose Of Review: Although many environmental exposures (e.g., air pollution) are geographically patterned and persist as a result of historic economic policies (e.

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Treatment choice is a key component of quality, person-centred care, but policies promoting choice often ignore how capacity to choose is unequally distributed and influenced by social structures. In abortion care, the choice of either medication or a procedure is limited in many countries, but the structuring of treatment choice from the perspective of people accessing abortion care is poorly understood. This qualitative study explored comparative experiences of abortion treatment choice in England and Wales, using in-depth interviews with 32 people who recently accessed abortion care and had one or more prior abortions.

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Background: Placenta accreta syndrome (PAS) may led to heavy blood loss and maternal death. Here we analyzed the main risk factors of PAS pregnancies and its complications in a referral hospital in the north of Iran.

Methods: In a case control study, all pregnant women with PAS referred to our department during 2016 till 2021 were enrolled and divided in two groups case (PAS+) and control (PAS-) based on preoperative imaging, intraoperative findings, and pathological reports.

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Introduction: In the first trimester, almost one in five identified pregnancies end in spontaneous miscarriage, and another 22% result in induced abortion. After a spontaneous and/or induced abortion, there may be retained products of conception (POC). Because of its relatively poor efficacy and the unpredictability of the time interval until spontaneous evacuation, expectant treatment is not often chosen by healthcare professionals.

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The incidence of first trimester pregnancy loss is around 10.0-20.0% of registered pregnancies.

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Background: Vaginal bleeding is the most common cause of presentation at the emergency department in the first trimester. Clinical presentation helps determine the likely cause of first-trimester vaginal bleeding. However, ultrasound imaging is required to reach a definitive diagnosis.

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Mechanism of chromosomal mosaicism in preimplantation embryos and its effect on embryo development.

J Assist Reprod Genet

May 2024

Department of Reproductive Medicine, The First Affiliated Hospital, Xi'an Jiaotong University of Medical School, Xi'an, 710061, Shanxi, P.R. China.

Aneuploidy is one of the main causes of miscarriage and in vitro fertilization failure. Mitotic abnormalities in preimplantation embryos are the main cause of mosaicism, which may be influenced by several endogenous factors such as relaxation of cell cycle control mechanisms, defects in chromosome cohesion, centrosome aberrations and abnormal spindle assembly, and DNA replication stress. In addition, incomplete trisomy rescue is a rare cause of mosaicism.

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Intrauterine adhesion in ultrasound-guided manual vacuum aspiration (USG-MVA) versus electric vacuum aspiration (EVA): a randomised controlled trial.

BMC Pregnancy Childbirth

February 2024

Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

Article Synopsis
  • Intrauterine adhesion (IUA) can occur after uterine surgeries, leading to complications during miscarriage management, and this study aimed to compare IUA rates between ultrasound-guided manual vacuum aspiration (USG-MVA) and electric vacuum aspiration (EVA) in women experiencing first-trimester miscarriage.
  • Conducted as a randomized controlled trial at a tertiary hospital, this study involved 303 Chinese women who underwent either USG-MVA or EVA, with follow-up assessments to evaluate IUA occurrence between 6 and 20 weeks post-surgery.
  • Results revealed that the IUA incidence was significantly lower in the USG-MVA group (19.0%) compared to the EVA group (32.0%), highlighting
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Objective: To determine headache diagnosis and treatment patterns in the outpatient setting, focusing on documentation of the International Classification of Headache Disorders (ICHD) criteria.

Design, Setting, And Participants: Retrospective cohort data were collected from electronic medical records of adults aged 18-35 who presented to resident-staffed family medicine outpatient clinics in the Midwest, USA, for a new or worsening headache between 2015 and 2016. Diagnosis codes were used to summarize the overall nature and prevalence of headaches.

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Decreased Expression of Placental Proteins in Recurrent Pregnancy Loss: Functional Relevance and Diagnostic Value.

Int J Mol Sci

February 2024

Systems Biology of Reproduction Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.

Article Synopsis
  • Miscarriages are common, occurring in 50-70% of pregnancies, with 1-5% of women experiencing recurrent pregnancy loss (RPL), which is defined as having two or more miscarriages.
  • Current understanding of the causes and mechanisms behind RPL is lacking, making reliable diagnostic and preventive methods unavailable.
  • The study assessed three placental proteins and found that lower levels of free-β-hCG and PAPP-A, particularly between 9-13 weeks of pregnancy, could serve as effective biomarkers for identifying RPL, suggesting issues with placental function and development.
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Background and objective ChatGPT and Google Bard AI are widely used conversational chatbots, even in healthcare. While they have several strengths, they can generate seemingly correct but erroneous responses, warranting caution in medical contexts. In an era where access to abortion care is diminishing, patients may increasingly rely on online resources and AI-driven language models for information on medication abortions.

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