2,323 results match your criteria: "Abortion Incomplete"
[Termination of pregnancy. Methods, results, and complications].
Laeknabladid
January 2025
Faculty of Medicine, School of Health Sciences, University of Iceland, Department of Obstetrics and Gynecology, Landspitali- The National University Hospital, Iceland.
Introduction: Medical treatment for termination of pregnancy in the first trimester of pregnancy was first introduced in 2006 at Landspitali. This new method, which replaced surgery, slowly gained ground and now most abortions in Iceland are medically induced. It is therefore appropriate to evaluate the effectiveness and safety of this method.
View Article and Find Full Text PDFReasons for unsafe abortion in Iran after pronatalist policy changes: a qualitative study.
Reprod Health
December 2024
School of Health and Welfare, Dalarna University, Högskolegatan 2, 79188, Falun, Sweden.
Background: In Iran, restrictive abortion laws have led to widespread unsafe abortions, posing significant health risks. The 2021 Family and Youth Protection Law further restricted access to reproductive health services in an effort to boost birth rates. The purpose of this qualitative study is to explore the reasons women sought abortions in an illegal context, based on their own experiences.
View Article and Find Full Text PDFReproductive performance and obstetric outcomes after hysteroscopic septum resection.
Eur J Contracept Reprod Health Care
December 2024
Etlik Zübeyde Hanım Women Health Education and Research Hospital, University of Medical Sciences, Etlik, Ankara, Turkey.
Purpose: The aim of this retrospective cohort study was to investigate the effects of hysteroscopic uterine septum resection on the clinical pregnancy rate (CPR), live birth rate (LBR) and miscarriage rate.
Materials And Method(s): Hospital records of consecutive patients who underwent hysteroscopic uterine septum resection between February 2021 and December 2022 were reviewed. They were telephoned and interviewed about their reproductive performance after surgery, and pregnancy outcomes, if achieved.
Evaluation of Femoston and Dydrogesterone therapy for incomplete abortion: a retrospective cohort study.
Gynecol Endocrinol
December 2024
Department of gynaecology and obstetrics, Women and Children's Hospital. School of Medicine, Xiamen University, Xiamen, Fujian Province, P.R. China.
Purpose: This study aimed to compare the efficacies of Femoston and Dydrogesterone therapy in patients with incomplete abortions.
Methods: Patients with incomplete abortions were included if they preferred medication over surgical intervention. The participants were categorized into three groups: the Femoston group received Femoston, the Dydrogesterone group was administered Dydrogesterone, and the control group was followed up without treatment.
Taohong siwu decoction ameliorates abnormal uterine bleeding via inhibiting ACSL4-mediated ferroptosis.
J Ethnopharmacol
January 2025
Department of Pharmacology, Anhui University of Chinese Medicine, Hefei, 230012, PR China.
Article Synopsis
- Taohong Siwu Decoction (TSD) is a traditional Chinese medicine used for centuries to treat blood stasis syndrome and may help with abnormal uterine bleeding (AUB) after incomplete abortion.
- The study aims to explore how TSD works by inhibiting ACSL4-mediated ferroptosis, a form of cell death related to inflammation and oxidative stress.
- Results showed TSD significantly reduced bleeding and inflammation, improved mitochondrial function, and altered markers related to ferroptosis, indicating its potential therapeutic effects on AUB.
Feasibility of neoadjuvant chemotherapy for bulky early stage to stage IIIB cervical cancer in Uganda.
Gynecol Oncol Rep
December 2024
Duke University Hospital, DUMC 3079, Durham, NC 27710, United States.
Article Synopsis
- - External beam radiotherapy (EBRT) was unavailable in Uganda for nearly two years, leading to the development of a new treatment strategy involving neoadjuvant chemotherapy (NAC) for bulky cervical cancer patients.
- - A study of 53 patients found that 75.5% completed the NAC protocol, with most receiving a platinum-taxane combination, and reported adverse events were mostly mild hematologic issues.
- - The findings suggest that even in a resource-limited setting, most patients successfully completed NAC with manageable side effects, and some went on to receive surgery and adjuvant therapy as needed.
Randomized Trial of Very Early Medication Abortion.
N Engl J Med
November 2024
From the Department of Women's and Children's Health, Division of Obstetrics and Gynecology (K.B., K.G.-D.), and the Department of Clinical Sciences at Danderyd Hospital (H.K.K.), Karolinska Institutet, and the Department of Obstetrics and Gynecology, Karolinska University Hospital (K.G.-D.), Stockholm, Södertälje Hospital, Södertälje (K.B.), the Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (T.J.-A., H.H.), the Department of Obstetrics and Gynecology, Skåne University Hospital, Malmö (P.T.), the Department of Clinical Sciences, Lund University Faculty of Medicine, Lund (P.T.), the Department of Clinical Sciences, Obstetrics, and Gynecology, Umeå University, Umeå (M.B.), and Statisticon, Uppsala (J.B.) - all in Sweden; the Centre for Reproductive Health, Institute for Regeneration and Repair, University of Edinburgh, and Chalmers Centre, NHS Lothian - both in Edinburgh (J.R.-W., S.C.); the Departments of Obstetrics and Gynecology (F.G., J.K., O.H.) and General Practice and Primary Health Care (F.G.), University of Helsinki and Helsinki University Hospital, Helsinki, and the Division of Health and Social Services, Wellbeing Services County of Vantaa and Kerava, Vantaa (F.G.) - both in Finland; the Center for Research on Environment, Health, and Population Activities, Kathmandu (A.T.), and KIST Medical College Teaching Hospital, Lalitpur (H.T.) - both in Nepal; Family Planning Australia, Sydney Medical School, University of Sydney, and the School of Public Health, University of Technology Sydney - all in Sydney (C.B.); Women's Health, Auckland City Hospital, Auckland, New Zealand (K.S., G.G.); the Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway (M.L.); and the Department of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre (M.M.K.), and the Hospital of Southern Jutland, Aabenraa (E.K.) - both in Denmark.
Article Synopsis
- The study investigated the effectiveness and safety of medication abortion using mifepristone and misoprostol in women up to 42 days of gestation without confirmed intrauterine pregnancy using ultrasound.
- A total of 1504 women were randomly assigned to either an early-start abortion group or a standard delayed care group, and the primary outcome measured was the rate of complete abortion.
- The results showed a nearly identical rate of complete abortion between the two groups (95.2% early-start vs 95.3% standard), indicating that starting medication abortion before confirming intrauterine pregnancy is as safe and effective as standard care.
Dan'e fukang decoction reduces hemorrhage in a rat model of mifepristone induced incomplete abortion and may correlate with cell adhesion molecule signaling interference.
J Ethnopharmacol
January 2025
NHC Key Lab of Reproduction Regulation, Shanghai Engineering Research Center of Reproductive Health Drug and Devices, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, China. Electronic address:
Article Synopsis
ITGA3 participates in the pathogenesis of recurrent spontaneous abortion by downregulating ULK1-mediated autophagy to inhibiting trophoblast function.
Am J Physiol Cell Physiol
October 2024
Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, China.
Article Synopsis
- Recurrent spontaneous abortion (RSA) occurs frequently in couples of reproductive age, with inadequate trophoblast invasion being a key factor in its development.
- Research indicates that integrins, especially integrin α-3 (ITGA3), play an important role in embryo implantation, but its role in miscarriage has not been well studied.
- This study found reduced ITGA3 levels in tissues from RSA patients, and through various methods, established that ITGA3 is crucial for trophoblast cell functions by regulating autophagy, ultimately affecting their ability to invade and migrate, contributing to RSA.
Delayed diagnosis of Herlyn-Werner-Wunderlich syndrome with diffuse adenomyosis in bilateral horns.
Radiol Case Rep
January 2025
National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Article Synopsis
- The Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital disorder characterized by a double uterus, obstruction of one side of the vagina, and absence of a kidney, usually affecting the right side, with symptoms often starting at puberty.
- Common issues experienced by individuals include pelvic pain, heavy menstrual bleeding, and infertility due to complications such as hematocolpos or hematometra, with potential long-term problems like endometriosis and increased risk of miscarriage.
- Diagnosis typically begins with an ultrasound, but MRI is preferred for confirming the syndrome and identifying associated anomalies; treatment often involves surgically removing the obstructed vaginal septum, as demonstrated in a case study of a 43-year
Article Synopsis
- Uterine perforation and herniation of abdominal organs can occur after gynecological procedures, but may be treated conservatively if the patient's condition is stable.
- The incidence of this complication is relatively low, ranging from 0.002% to 1.7% during surgeries like suction curettage.
- A specific case of a 30-year-old woman revealed that proper gynecological assessments, including clinical exams and ultrasounds, are crucial after such procedures to catch complications early.
Virtual reality for the management of pain and anxiety during outpatient manual vacuum aspiration for miscarriage or incomplete abortion: a mixed methods trial.
Eur J Contracept Reprod Health Care
December 2024
Department of Obstetrics & Gynaecology, Whipps Cross University Hospital, London, United Kingdom.
Article Synopsis
- The study aimed to assess the effectiveness of virtual reality (VR) as a distraction method for managing pain and anxiety during outpatient uterine aspiration procedures.
- Involving 50 participants, the study compared VR intervention with standard care, measuring pain and anxiety scores before and after the procedure, along with conducting qualitative interviews.
- Results showed no significant difference in pain and anxiety between the two groups, but the majority of VR users reported a positive experience, indicating that while VR may not reduce pain or anxiety scores, it is still a viable and acceptable option for enhancing patient comfort.
Spontaneous rupture of an unscarred uterus at the early third trimester due to placenta percreta: a case report.
J Int Med Res
October 2024
Department of Obstetrics and Gynecology, Ningbo Women and Children's Hospital, Ningbo, China.
Article Synopsis
- - A case study details a woman in her 30s who experienced uterine rupture at 30 weeks of pregnancy, linked to placenta percreta, after having previous abortion treatment.
- - She was admitted for abdominal pain and vomiting and had thrombophilia, leading to anticoagulant treatment; however, her condition worsened suddenly, requiring emergency cesarean delivery.
- - Uterine rupture from placenta percreta is rare but serious, highlighting the need for careful monitoring of pregnant women with severe abdominal pain; individualized treatment and uterine repair are often feasible.
Performance of Computer-Aided Detection and Quality of Bowel Preparation: A Comprehensive Analysis of Colonoscopy Outcomes.
Dig Dis Sci
October 2024
Division of Gastroenterology and Hepatology, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35205, USA.
Article Synopsis
- The study investigates how an artificial intelligence (AI) tool improves the detection of colorectal polyps during colonoscopy, particularly for patients with poor bowel preparation.
- Using a case-control design and propensity score matching, researchers analyzed data from 2017 to 2023 to compare colonoscopies performed with and without AI assistance.
- Results show that AI significantly increased the detection rates of various types of polyps, especially in patients with inadequate preparation, highlighting its potential role in enhancing colonoscopy outcomes.
Adverse Events of Femtosecond-Assisted Laser-Assisted Keratomileusis: A Manufacturer and User Facility Device Experience Database Study.
J Curr Ophthalmol
August 2024
Manhattan Eye, Ear and Throat Hospital, New York, New York, USA.
Article Synopsis
- The study analyzes the FDA's MAUDE database to identify and characterize adverse events linked to femtosecond (FS) laser-assisted LASIK surgeries from January 2012 to April 2022.
- A total of 1,136 relevant adverse events were identified from 3,491 reports, with common intraoperative complications being incomplete cuts and difficulties with the flap, while diffuse lamellar keratitis (DLK) was the most frequent postoperative issue.
- This research highlights the prevalence of specific complications during and after FS-assisted LASIK and aims to improve awareness and patient counseling for ophthalmologists.
Witzenberg Women's experience of health care after a miscarriage: A descriptive qualitative study.
Afr J Prim Health Care Fam Med
August 2024
Department of Family and Emergency Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch.
Article Synopsis
- The study investigates women's experiences with healthcare during incomplete miscarriages in Witzenberg, South Africa, where no prior data exists on the topic.
- Through in-person, semi-structured interviews with eight women, five key themes emerged: safety needs, pain management concerns, challenging healthcare interactions, disorientation within the healthcare system, and feelings of abandonment.
- The conclusion emphasizes the importance of providing respectful, supportive care, clear communication, and emotional support for women facing early pregnancy complications in rural areas.
Predictors of successful expectant and medical management of miscarriage: A systematic review.
Acta Obstet Gynecol Scand
December 2024
Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.
Article Synopsis
- 15.3% of pregnancies result in miscarriage, and various management options exist (expectant, medical, surgical), but individual patient factors complicate decision-making.
- The systematic review analyzed data from multiple databases up to April 2023, focusing on defined predictors for successful miscarriage management while excluding low-quality studies.
- Key findings suggest that demographics, ultrasound features, and biochemical markers influence management outcomes, with incomplete miscarriages showing a higher success rate for expectant or medical management, highlighting the need for more extensive and standardized research to aid in personalized patient care.
Comparative seropositivity of in the serum of pregnant women with and without a history of abortion by serological and culture methods.
SAGE Open Med
July 2024
Department of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Article Synopsis
- The study aimed to investigate the presence of listeriolysin O antibodies in pregnant women to help identify listeriosis and its potential link to miscarriage or infection.
- Clinical samples from 120 pregnant women were analyzed using culture methods and an Enzyme Linked Immuno-Sorbent Assay (ELISA) to detect these antibodies, revealing a positivity rate of 24.16% by culture and 28.3% by ELISA.
- Ultimately, no significant correlation was found between the presence of these antibodies and the history of miscarriages in the participants, although the study results should be interpreted cautiously due to some limitations.
Uretero-uterine fistula following Manual Vacuum Aspiration for Incomplete abortion: A rare case report.
Radiol Case Rep
September 2024
Department of Radio Diagnosis and Imaging, Shree Birendra Hospital, NAIHS, Kathmandu, Nepal.
Article Synopsis
A qualitative exploration of the reasons and influencing factors for pregnancy termination among young women in Soweto, South Africa: a Socio-ecological perspective.
Reprod Health
July 2024
SA MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Private Bag X3, Wits, Johannesburg, 2050, South Africa.
Article Synopsis
- Pregnancy termination is a significant aspect of reproductive healthcare in Southern Africa, with 23% of pregnancies ending this way, highlighting the need to understand the various influencing factors, including personal and social contexts.
- A study conducted in Soweto used in-depth interviews with ten women aged 18-28 who had undergone termination to explore reasons and decision-making influences, employing a socio-ecological framework for analysis.
- Results showed that key reasons for termination included financial insecurity and lack of support, while broader socio-ecological factors such as social support networks and access to services also played crucial roles in the decision-making process, particularly impacted by the COVID-19 pandemic.
Article Synopsis
- - Tubal abortion refers to the expulsion of a fetus into the abdominal cavity from a fallopian tube, which can be either complete or partial, and is a type of ectopic pregnancy that poses challenges in accurately determining its incidence.
- - Accurate diagnosis of tubal abortions is essential for tailored treatment, typically involving ultrasound imaging, measuring b-hCG levels, and visual confirmation during surgery.
- - A case study of a 30-year-old woman with suspected ectopic pregnancy revealed a tubal abortion via laparoscopic surgery, allowing for a conservative treatment that preserved her fallopian tubes and potential fertility.
The Success of Mifepristone and Misoprostol in the Management of Early Pregnancy Loss at a Community Hospital: A Prospective Study.
J Obstet Gynaecol Can
September 2024
Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON; Department of Obstetrics and Gynecology, North York General Hospital, Toronto, ON.
Article Synopsis
- This study aimed to assess how effective a treatment regimen is for managing early pregnancy loss (EPL) by measuring the expulsion rate of the gestational sac.
- Out of 441 participants, 188 were eligible, and those who followed the treatment protocol saw a 93.3% success rate in complete expulsion of the gestational sac after 14 days.
- The findings suggest that using mifepristone and misoprostol is a safe and effective option for managing EPL, although some participants were later diagnosed with retained products of conception.
Hydroxychloroquine in recurrent pregnancy loss: data from a French prospective multicenter registry.
Hum Reprod
September 2024
Service de Médecine Interne et Inflammation-Immunopathology-Biotherapy Department (DMU I3), Hôpital Saint Antoine, Sorbonne Université AP-HP, Paris, France.
Article Synopsis
- The study investigates the outcomes of pregnancies in women with recurrent pregnancy loss (RPL) who were treated with hydroxychloroquine (HCQ) during early pregnancy, identifying that previous miscarriage count was the primary factor affecting pregnancy success.
- HCQ is explored as a potential treatment due to its effects on the maternal immune system, which may be linked to unexplained RPL.
- The study utilized the FALCO registry, which includes women with a history of RPL, to analyze pregnancies while excluding those with certain concurrent treatments, focusing on pregnancy continuation beyond 12 weeks and live births.
Causal Relationship Between Circulating Immune Cells and Recurrent Spontaneous Abortion: A Bidirectional Mendelian Randomization Study.
Am J Reprod Immunol
June 2024
Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai Medical College, Shanghai, China.
Article Synopsis
- Recurrent spontaneous abortion (RSA) is a complex pregnancy issue influenced by various factors, especially immunologic ones, and this study investigates the role of immune cells in RSA.
- The researchers conducted a Mendelian randomization study analyzing 731 immune cell types to determine their causal effects on spontaneous abortions and recurrent miscarriages, while also addressing potential biases.
- The study found eight immune cell markers significantly linked to spontaneous abortions and identified two markers related to recurrent miscarriage, demonstrating a clear immune component in these reproductive challenges without signs of bias or alternative explanations.
The yield of a comprehensive investigation protocol for the diagnosis of true idiopathic ventricular fibrillation in a real-life clinical setting.
Sci Rep
June 2024
Department of Internal Medicine and Cardiology, University Hospital Brno and Faculty of Medicine, Masaryk University, Jihlavska 20, 625 00, Brno, Czech Republic.
Article Synopsis
- * Researchers analyzed data from 514 ACA patients, identifying 46 who met specific criteria for an advanced diagnostic work-up, which included various imaging and testing methods.
- * Results showed that 37% of patients had a specific disease discovered, while true idiopathic VF was confirmed in only 15.2%, suggesting that even partial diagnostic efforts can lead to meaningful findings for targeted treatment.