1 results match your criteria: "Abderrahmen Mami Hospital of Pulmonology[Affiliation]"
Detection of isoniazid and rifampin resistance of Mycobacteriumtuberculosis by a multiplex allele-specific polymerase chain reaction (PCR) assay.
Int J Mycobacteriol
March 2012
Mycobacteria Reference Laboratory, Abderrahmen Mami Hospital of Pulmonology, Ariana, Tunisia; Faculty of Pharmacy, Monastir, Tunisia. Electronic address:
Background: The use of molecular techniques is a major improvement for the rapid routine detection and control of multidrug-resistant tuberculosis (MDR-TB).
Materials: In this study, the multiplex allele-specific polymerase chain reaction (MAS-PCR) was developed to simultaneously detect the most frequent mutations associated with isoniazid (INH) and rifampin (RIF) resistance in a single assay.
Results: The assay was tested with 53 clinical isolates.