1,310 results match your criteria: "Abdelmalek Esaâdi University[Affiliation]"

Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a rare condition in children that causes acute, severe, but often reversible systolic dysfunction of the left ventricle. Physical trauma is a recognized trigger, although distinguishing TTC from myocardial contusion in pediatric trauma cases can be challenging due to overlapping clinical features. We present the case of a six-year-old boy involved in a high-impact motor vehicle collision.

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  • A new Sonogel-Carbon (SNGC) electrode, enhanced with the amino acid l-leucine, has been created for detecting homovanillic acid (HVA) effectively.
  • Electrochemical techniques like cyclic voltammetry and impedance spectroscopy confirmed the performance of the SNGC-Leu electrode, which demonstrated a linear detection range for HVA from 0.5 μM to 50 μM and a detection limit of 0.4 μM.
  • The SNGC-Leu sensor showed high accuracy in real applications, successfully measuring HVA in human urine and synthetic cerebrospinal fluid with impressive recovery rates.
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Chronic Kidney Disease of Unknown Etiology: A Global Health Threat in Rural Agricultural Communities-Prevalence, Suspected Causes, Mechanisms, and Prevention Strategies.

Pathophysiology

December 2024

Laboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, PO 1893, Km 2200, Route Sidi Harazem, Fez 30000, Morocco.

Chronic Kidney Disease of Unknown Etiology (CKDu) is a worldwide hidden health threat that is associated with progressive loss of kidney functions without showing any initial symptoms until reaching end-stage renal failure, eventually leading to death. It is a growing health problem in Asia, Central America, Africa, and the Middle East, with identified hotspots. CKDu disease mainly affects young men in rural farming communities, while its etiology is not related to hypertension, kidney stones, diabetes, or other known causes.

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Marine algae are renowned for their health benefits due to the presence of functional bioactive compounds. In this context, this study aims to valorize the extract of a seaweed, (), through phytochemical characterization using liquid chromatography-mass spectrometry (HPLC-MS), as well as in vitro and in silico evaluation of its biological activities (antioxidant and antimicrobial). Phytochemical characterization revealed that the ethanolic extract of (DdEx) is rich in phenolic compounds, with a total of 22 phycocompounds identified.

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Marine sulfated polysaccharides constitute a class of bioactive polymers commonly found in cell walls of macroalgae. Among these macromolecular substances, fucoidans, ulvans, and carrageenans have attracted considerable attention providing interesting therapeutic properties affected by a combination of various structural factors, such as sulfation pattern, molecular weight, monosaccharide composition, and glycosidic linkages. Remarkably, chemical modification, enzymatic hydrolysis and crosslinking are promising approaches for developing the application of these polysaccharides through enhancement and/or addition of new biological properties.

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Hydatid disease is a zoonotic infection caused by the tapeworm, primarily affecting the liver and lungs, and rarely involving muscle tissue. Humans are infected by ingesting eggs from contaminated food or water. Patients may present with painless, slow-growing masses, sometimes associated with nerve or vessel compression, especially in cases of muscle involvement.

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Auditory brainstem responses as a biomarker for cognition.

Commun Biol

December 2024

Center for Hearing Research, Otolaryngology-Head and Neck Surgery, University of California Irvine, Irvine, CA, USA.

A non-invasive, accessible and effective biomarker is critical to the diagnosis, monitoring and treatment of age-related cognitive decline. Recent work has suggested a strong association between auditory brainstem responses (ABR) and cognitive function in aging macaques. Here we show in 118 human participants (66 females; age range=18-92 years; hearing loss = -5 to 70 dB HL) that cognition is associated with both age and hearing level, but this triad relationship is mainly driven by the age factor.

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Background: In Morocco, latent tuberculosis infection (LTBI) is a public health concern affected by the country's location as transit area between sub-Saharan Africa with high TB burden to Europe. This study aimed to assess the influence of exposure intensity to Mycobacterium tuberculosis (Mtb), age, and Bacille Calmette-Guérin (BCG) vaccination on LTBI prevalence in Morocco.

Methods: A cross-sectional study of 131 participants, including 98 non-exposed healthy volunteers (NEHV) and 33 healthcare workers exposed to active TB (exposed healthcare workers [EHCW]), was conducted.

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Because college students are an important category of the population highly vulnerable to mental health problems, this study aims to investigate the sociodemographic variables associated with the increase in psychological distress levels among Moroccan college students. Participants ( = 1147; mean age 20.00, = 2.

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Anticancer Effect of Mycotoxins From : Exploration of Natural Product Potential.

Int J Microbiol

December 2024

Department of Biology, Laboratory of Research and Development in Engineering Sciences, Faculty of Sciences and Techniques of Al-Hoceima, Abdelmalek Essaadi University, Tetouan 93000, Al-Hoceima, Morocco.

Research into biologically natural substances with antitumor properties, known for their potential to induce fewer side effects and exhibit specificity toward cancerous cells, remains imperative. The pressing demand for novel agents in cancer therapy underscores the intensive investigation of natural products from microorganisms. , frequently isolated from food and feed, emerges as a promising candidate against pathogenic bacteria and fungi.

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  • The Mauritanian Atlantic coast is crucial for both the economy and ecosystem but is facing pollution from human activities, particularly PAH contamination.
  • To evaluate this pollution, the coast was categorized into four zones, revealing that the most contaminated zones (PNkt and LBZ) had significantly higher PAH levels in sediments compared to the less stressed zones (PNBA and PDlt).
  • The findings indicate heightened risks for both carcinogenic effects and ecological damage in the more polluted zones, emphasizing the need for sustainable management of the coastal resources in Mauritania.
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Current and emerging strategies for the prevention of hepatocellular carcinoma.

Nat Rev Gastroenterol Hepatol

December 2024

Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Liver cancer is the third leading cause of cancer-related deaths globally, with incident cases expected to rise from 905,700 in 2020 to 1.4 million by 2040. Hepatocellular carcinoma (HCC) accounts for about 80% of all primary liver cancers.

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Plastic pollution in a special protected area for migratory birds.

Sci Total Environ

December 2024

Department of Mathematical and Computational Sciences, Physical Science and Earth Science, University of Messina, Messina, Italy; Institute for Chemical-Physical Processes, National Research Council of Italy (IPCF-CNR), Messina, Italy.

Plastic pollution in Special Protected Areas for Migratory Birds and Sites of Community Importance is a growing environmental concern. These areas, often designated to provide safe habitats for migratory bird species, are increasingly threatened by plastic litter. In this study, we conducted the first assessment of plastic litter, ranging from macro to microplastics, in beach sediments from two sites (Montorsoli Beach and Pylon Beach) along the coast of the Strait of Messina, a Special Protected Area, to assess beach quality and ecological risk.

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A checklist of water beetles of the family Hydrochidae from Morocco is presented. The study compiles data gathered from a deep literature review and field surveys at 397 freshwater localities between 1985 and 2023. The checklist also contains information concerning type localities and detailed distributions for the eight species found.

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The first record of a European black fly, Simulium ichnusae Rivosecchi & Contini, is documented for Africa, where it was found at elevations above 1000 m in the Djurdjura Mountains of Algeria. Considered an endemic species of Sardinia for 60 years, S. ichnusae must now be regarded as pseudoendemic.

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Monitoring the Overall Quality of Groundwater Using a Geographic Information System in the Angads Plain (Oujda, Morocco).

ScientificWorldJournal

November 2024

Biology Department, Health and Environment Laboratory, Faculty of Science, Natural Resources Management and Development Team, Moulay Ismail University, Meknès, Morocco.

The future of groundwater is one of the key challenges for sustainable water management, hence the need to monitor its overall quality. The objective of this work is to assess the overall quality and determine the spatiotemporal evolution of the Angads aquifer in northeastern Morocco in 2014 and 2020, based on the parameters NH , NO , EC, Cl, and FC, as well as the Geographic Information System (GIS). The results of the comparison of these five parameters between 2014 and 2020 show a general increase in NH and a decrease in NO and FC at most sampling points.

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Background: Viral hepatitis B and C are the leading causes of hepatocellular carcinoma (HCC). With obesity, metabolic-related disorders are increasingly associated with a higher incidence of nonviral HCC. This study aimed to investigate the characteristics, tumor features, treatment outcomes, and survival of patients with viral versus nonviral HCC.

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Article Synopsis
  • - Cervical spondylotic myelopathy (CSM) is a condition caused by spinal cord compression due to disc degeneration, traditionally treated with anterior cervical discectomy and fusion (ACDF), which may lead to complications like adjacent segment disease (ASD).
  • - This study retrospectively compared the effectiveness of ACDF and cervical disc arthroplasty (CDA) in treating CSM in 110 matched patients (55 in each group) over a minimum follow-up of two years.
  • - Results showed no significant differences in demographics, complication rates, or patient-reported outcomes between the ACDF and CDA groups, indicating that both surgical options may be equally effective for patients with CSM.
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This study explores the application of a dopamine-assisted co-deposition strategy to modify the surface of daily disposable silicone hydrogel contact lenses. Aiming to enhance the hydrophilicity of these typically hydrophobic lenses, we developed an industry-friendly process using simple dip coating in aqueous solutions. By co-depositing tannic acid, dopamine and chitosan derivative and employing periodate oxidation, we achieved a rapid and efficient coating process.

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The Ouislane sub-watershed is currently experiencing severe water shortages and is highly dependent on its water supply. The sub-watershed spans two communes: Meknes to the north and El Hajeb to the south. It serves as the primary water source for irrigation and drinking purposes for the local population.

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Congo Red (CR) dye is classified as a toxic and carcinogenic substance, posing significant health and environmental risks. To address this issue, the adsorption efficiency of CR on natural bentonite and hydroxyapatite (HA) was systematically studied. The adsorbents were successfully characterized by XRD, FTIR, and SEM analysis.

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HHH whitepaper.

Eur Phys J C Part Fields

November 2024

Department of Physics, University of Wisconsin, Madison, WI 53706 USA.

Article Synopsis
  • - The HHH Workshop held in Dubrovnik in July 2023 focused on advancing the understanding of the Higgs boson and its properties within the Standard Model (SM).
  • - To confirm or challenge the SM, researchers need to measure the full potential of the Higgs, including the triple and quartic scalar couplings, particularly involving three scalar bosons at around 125 GeV.
  • - The report highlights ongoing experimental efforts and theoretical models aimed at improving measurement rates and addressing challenges related to multi-scalar final states.
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