Erotomania following an orchiectomy: a case report.

A case report of young male patient with erotomania following seminoma and orchiectomy is described in this article. The probable dynamics that lead to this delusion are then discussed. This case report demonstrates the cooperation between the oncology ward and the psychiatric liaison service.

Heterogeneity in adducted thumbs sequence.

We report on a boy with adducted thumbs, microcephaly, swallowing difficulties, hypotonia, and severe mental retardation, but without craniostenosis or arthrogryposis. An MRI scan showed myelinization according to age and mild ventricular enlargement. A muscle biopsy documented irregular-shaped and swollen mitochondriae, but results of mitochondrial function tests were normal.

[Between "transparent room" and "sealed room:" professional confidentiality and therapeutic judgement].

Patients and therapists are concerned with the complexities of protecting medical confidentiality. The traditional perception of protection of patient confidentiality is that the individual's interest in protecting his confidentiality may conflict with the public's need for information, especially in cases involving possible danger. In fulfilling his dual role of representing both the patient and the public, the therapist acts according to existing laws and regulations.

Screening for Human T-cell Lymphotrophic Virus type-I (HTLV-I) infection in high risk schizophrenic patients.

The Mashhadi-Jewish community originating in Iran is a closed and ethnically segregated population with a unique history and a high rate of intra-familial marriage among its members. High infection rate (23%) by Human T-Lymphotrophic Virus type-I (HTLV-I) was found in this population. The known modes of HTLV-I transmission are by sexual intercourse, from mother to child in breast milk, via blood transfusion, and by sharing of needles by parenteral drug users.

Hepatitis among psychiatric inpatients: a high-risk group?

Viral hepatitis B (HBV) and C (HCV) have been reported to be prevalent among residents of custodial institutions and health-care workers. Among psychiatric inpatients sparse research was undertaken and results are controversial. We designed the present study to evaluate rates of HBV and HCV among psychiatric inpatients and to characterize the "typical" carriers.

Acute neuroleptic induced leukopenia in Ethiopian jews with benign familial leukopenia.

Benign familial leukopenia (BFL) has been described in various ethnic groups around the world; in Israel it is found among Yemenites and Ethiopians. Neuroleptics infrequently cause acute leukopenia. We described nine Ethiopian subjects who were treated with conventional antipsychotics for four weeks.

Insight and competence to consent to psychiatric hospitalization.

Informed consent and insight are among the most important issues in medical treatment, especially for psychiatric patients. In this study, we examined the competence to consent to psychiatric hospitalization of 113 psychiatric patients who were voluntarily admitted to a mental hospital in various psychotic states and compared it with their insight. We found a significant correlation between the patients' competence and insight into their illnesses.

The views of psychiatric patients and their treating physicians of court-ordered compulsory hospitalization for criminal acts.

The legal responsibility for the mentally ill has long been a dilemma. Public opinion regarding the law which states that the mentally ill, in a psychotic state, are not responsible for their actions, is divided. The study assessed 30 psychiatric patients, committed by court order, following a criminal act on their part.

To inform or not to inform--a decision with psychobiological implication.

A patient, being informed about his dangerous or even fatal disease, like cancer, has a higher chance to give up and display a renunciation of search activity. Such renunciation decreases body resistance and makes the overall situation hopeless. Thus a person has the right to be not informed about such diseases, because he has the right to use all his inner resources for survival.

Inositol treatment of autism.

Recent studies suggest that serotonin reuptake inhibitors are helpful in at least some symptoms of autism. Inositol is a precursor of the second messenger for some serotonin receptors, and has been reported effective in depression, panic disorder and obsessive-compulsive disorder. However a controlled double-blind crossover trial of inositol 200 mg/kg per day showed no benefit on 9 children with autism.

Hospitalized mentally ill patients in Israel vote for the first time.

For the first time in Israel, hospitalized mentally ill patients were enabled to participate in the election of the prime minister and members of the Knesset (Israeli parliament) held on May 29, 1996. In a demonstration election held in Yehuda Abarbanel Hospital to teach and prepare the patients to vote, the outcome of the vote for the prime minister was identical to the results of the general public vote. The sample vote results for members of the Knesset were slightly different from those in the actual election.

The effect of chlorpromazine and haloperidol on DNA transcription.

The ability of human cells to repair DNA damage can be indirectly assessed by measuring transcriptional activity relating to active genes, a process referred to as RNA synthesis. This study was carried out to investigate the effects of chlorpromazine and haloperidol on the transcriptional activity of actively transcribed genes as an expression of DNA damage and repair. Three cultured human fibroblast lines were used: two were "normal" in previous RNA recovery testings and one was abnormally sensitive to UV irradiation.

Psychoneuroimmunology: searching for the main deteriorating psychobehavioral factor.

Psychoneuroimmunology has become an independent science with a broad experimental basis. However, its theoretical basis is still very vague and ambiguous. There are many contradictions in the experimental data that have not been integrated into a united conception, and some accepted paradigms that remain doubtful.

Sexual dysfunction in relapsing-remitting multiple sclerosis: magnetic resonance imaging, clinical, and psychological correlates.

The purpose of this study was to examine the sexual complaints and severity of sexual dysfunction in relapsing-remitting multiple sclerosis patients and to correlate them with psychological, neurological, and radiological variables. Frequency and characteristics of sexual disturbances were reported by 41 multiple sclerosis patients (32 females, 9 males; mean age 35.4 +/- 10.

Neuroleptic-resistant schizophrenia treated with clozapine and ECT.

Despite advancement in psychopharmacology, treatment-resistant schizophrenia still poses a challenge to modern psychiatry. We present four patients with schizophrenia treated with clozapine and ECT. One patient who developed neuroleptic malignant syndrome (NMS) on conventional neuroleptics experienced no complications with this combination.

[Seroquel in a resistant schizophrenic with negative and positive symptoms].

Refractoriness to treatment is a common problem in management of schizophrenics. Conventional pharmacotherapy is usually effective in controlling positive symptoms of the disease, such as delusions and hallucinations. However, they have restricted ability to affect negative symptoms (flat affect, social withdrawal) and to reverse functional disability and behavioral deviance.

Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.

1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2.

The impact of the Gulf War on the mental health of schizophrenic patients.

The Gulf War, which took place during January-February 1991, strongly affected the lives of Israeli civilians. The missiles that landed on the home front were a threat to the entire civilian population, thus differentiating the Gulf War from prior Israeli wars (Danon and Shemer 1991). This was similar to the London blitz during World War II (Scoville 1942).

Serum and cerebrospinal levels of calcium and magnesium in acute versus remitted schizophrenic patients.

Serum and cerebrospinal fluid levels of calcium and magnesium were measured in acute schizophrenics versus schizophrenic patients in remission. The acute schizophrenics demonstrated statistically significant lower levels of cerebrospinal fluid magnesium. The mechanism that underlies this difference is not clear.

Brainstem auditory evoked potentials of panic disorder patients.

Panic attacks are subjectively reported by patients as a cluster of autonomic nervous symptoms. Taken together with the evidence from pharmacological studies focusing on the locus ceruleus and the dorsal raphe nuclei, the hypothesis of brainstem involvement in panic attacks is of major interest. Functional evaluation of the brainstem is carried out using electrophysiological recordings, such as the brainstem evoked potentials.

Requalifying examination and employment in immigrant physicians as predictors of successful immigration to Israel.

Thirty physicians who immigrated together from South America to Israel were followed during their first two years in Israel. Success in the medical requalifying examination and finding work as physicians correlated directly with permanency in Israel, and, inversely, returning to country of origin was associated with being unqualified and unemployed. Age, sex, marital status, religion and previous professional status were not associated with permanency in Israel.

The efficacy of amitriptyline and acetaminophen in the management of acute low back pain.

Thirty-nine patients with acute low back pain were treated with amitriptyline (150 mg/d) or acetaminophen (2,000 mg/d) in a controlled double-blind design for 5 weeks. Both groups revealed mild depression, normal coping, and increased anxiety at the beginning, with significant improvement in anxiety state and pain at the end of treatment. A repeated measures analysis of variance demonstrated that amitriptyline was more effective than acetaminophen in reducing pain intensity from the second week of treatment.

Maintaining schizophrenic patients on benzodiazepines.

The role of benzodiazepines (BZDs) in the treatment of schizophrenia is widely researched since the sixties. Nevertheless the role of BZD's as sole agents for the maintainance phase in pharmacotherapy of schizophrenic patients received little attention. We have conducted a retrospective review of all medical records of ambulatory schizophrenic patients in an out-patient setting receiving only BZD maintainance treatment.

[Once upon a time there was a schizophrenic].

A series of 4 schizophrenic patients is described. In 2 it was unequivocally shown that acute outbreaks of "positive" symptoms were expressions of intrapsychic conflicts and in 1, the result of a therapist's error. In the first case, when the conflict was resolved, symptoms disappeared.

Disabling compulsions in 11 mentally retarded adults: an open trial of clomipramine SR.

Background: Clinicians and researchers who work with mentally retarded subjects have reported on the frequent exhibition of mental disorders and behavioral problems in this population. Rituals are often among the disturbances described. We decided to treat disabling cleaning and collecting compulsions in mentally retarded adults with clomipramine 75 mg/day, sustained release (SR) preparation.